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    South Carolina Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
    3,014 properties
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    Class A Office Space Available
    Class A Office Space Available

    4401 Leeds Avenue, North Charleston, SC 29405

    Wando Woods
    $34.50 SF/Yr
    33–56 people  8,452 sqft

    Four-story, 102,024 SF Class A office building for lease.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    6290-6000 Woodside Executive Ct, Aiken, SC 29803

    $1,200/Mo
    2–4 people  736 sqft

    Second-floor suite includes a waiting area, three offices, in-suite bathroom, and wet bar with stair access only.

    Wet bar
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    14-Office Commercial Suite
    14-Office Commercial Suite

    404-A Main St., North Myrtle Beach, SC 29582

    $4,800/Mo
    12–20 people  3,000 sqft
    14 private offices  Road access

    Commercial zoning and separate access from Main Street and 1st Street support office, retail, or service use.

    Pole Road Sign  Storage
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    Industrial Space with Flexible Term
    Industrial Space with Flexible Term

    200 Masters Blvd, Anderson, SC 29626

    $5.25 SF/Yr
    108,000 sqft  Built 1998

    Approximately 108,000 square feet of industrial space is available for lease through January 1, 2028.

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    Medical Office Park Buildings
    Medical Office Park Buildings

    3700 Forest Dr, Columbia, SC 29204

    $22 SF/Yr
    600–1,000 people  3 spaces  150,000 sqft  Built 1973

    Two office/medical buildings comprise an approximately 150,000 RSF park on Forest Drive.

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    Office Space with High-End Finishes
    Office Space with High-End Finishes

    386 Spanish Wells Rd, Unit B-3, Hilton Head Island, SC 29926

    $3,000/Mo
    8–14 people  1 space  2,175 sqft  Built 1986

    Office space featuring high-end finishes in a desirable location.

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    Restaurant Building with On-Site Parking
    Restaurant Building with On-Site Parking

    220 Georgia Avenue, North Augusta, SC 29841

    $2,800/Mo
    1,440 sqft  Built 1966

    The property connects to Augusta and North Augusta via Georgia Avenue, with shopping nearby.

    16 parking spaces
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    Historic Arcade Mall Retail Space
    Historic Arcade Mall Retail Space

    1332 Main St, Columbia, SC 29201

    Downtown Neighborhood Association
    $600/Mo
    39,320 sqft

    Historic indoor shopping center with high-end finishes in downtown Columbia.

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    Updated Office Suite with Private Offices
    Updated Office Suite with Private Offices

    413 Vardry Street, Greenville, SC 29601

    $2,500/Mo
    0.15 acres
    5 private offices  1 meeting rooms

    Updated workspace includes private offices, conference facilities, reception, and an ADA bathroom.

    5 parking spaces  ADA bathroom  Overflow parking
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    Climate-Controlled Manufacturing & Warehouse
    Climate-Controlled Manufacturing & Warehouse

    685 Monitor Drive, Anderson, SC 29626

    Triple net (NNN)
    $6.50 SF/Yr
    19,000 sqft  1 docks + 5 drive-in  600A 480V 3-phase

    Enclosed climate-controlled manufacturing with covered outdoor storage on a fenced and gated, well-served site.

    Outdoor storage  Fenced yard
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    Office Space For Lease
    Office Space For Lease

    1310 Harden Street, Columbia, SC 29204

    Cottontown / Bellevue Historic District
    $2,500/Mo
    12–20 people  1 space  3,000 sqft

    Office space for lease with newly renovated interior.

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    Flex/Warehouse Building with Roll-Up Doors
    Flex/Warehouse Building with Roll-Up Doors

    1906 Dobbins Bridge Rd, Anderson, SC 29624

    $12 SF/Yr
    5,400 sqft  18 ft clear  200A  Built 2025

    Built in 2025, the insulated facility can be divided into two units and has single-phase electrical service.

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    Class A Office Space
    Class A Office Space

    100 Calhoun Street, Charleston, SC 29401

    Garden District
    $43 SF/Yr
    38–64 people  9,675 sqft

    Multi-tenant office building in Charleston's Historic District.

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    Industrial Lot with Office, Warehouse
    Industrial Lot with Office, Warehouse

    4182 Tilly Swamp Road, Conway, SC 29526

    $3,000/Mo
    2,000 sqft

    Industrial lot featuring office trailer and warehouse near Highway 90.

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    Office-Warehouse Flex Suite
    Office-Warehouse Flex Suite

    2132 Carolina Place Drive, Fort Mill, SC 29708

    Triple net (NNN)
    $3,500/Mo
    16 ft clear  1 drive-in  Built 2000
    Highway access

    A glass-fronted office component pairs with warehouse space in a practical layout for client visits and operations.

    Reception area  Conference room
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    Professional Office Suite
    Professional Office Suite

    1101 Johnson Avenue Unit 302, Myrtle Beach, SC 29577

    $27 SF/Yr
    173–288 people  1 space  43,323 sqft  Built 2008

    Professional office space in The Offices at Market Common, located between Highway 17 Business and Highway 17 Bypass.

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    Industrial Flex Space with Office
    Industrial Flex Space with Office

    1445 Cannon Rd, Myrtle Beach, SC 29577

    $12.75 SF/Yr
    2,400 sqft  200A  Built 1996

    Functional industrial suite combining warehouse space, a finished office, and a roll-up door for operational flexibility.

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    Office Unit at Corner Location
    Office Unit at Corner Location

    501 S Wise Drive, Sumter, SC 29150

    $1,660/Mo
    5–9 people  1,459 sqft

    Office rental with CAM covering parking lot and landscape maintenance, area lighting, property tax, and insurance overages.

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    Flexible Office Unit
    Flexible Office Unit

    1604 2nd Loop Rd, Florence, SC 29501

    $1,800/Mo
    4–6 people  1,000 sqft

    Commercial space with adaptable layout, parking, and access for office, medical, retail, or service businesses.

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    Office Units with Fenced Yard
    Office Units with Fenced Yard

    1505 Mt Holly Road, Rock Hill, SC 29730

    $4,200/Mo
    1 space  1,200 sqft  Built 1970  1 acre
    Highway access + Road access

    Lease opportunity with dedicated office space, three-phase power, and a secured gravel yard for operational flexibility.

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    Light Manufacturing Facility with Office
    Light Manufacturing Facility with Office

    185 Exchange Logistics Park Dr, Piedmont, SC 29673

    $11 SF/Yr
    34,488 sqft  Built 2022
    Highway access

    Light manufacturing facility includes fully sprinkled, heated warehouse and 2,088 SF conditioned office with private offices and lobby.

    Sprinklered
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    Retail Space with Monument Signage
    Retail Space with Monument Signage

    71 Da Gullah Way, Pawleys Island, SC 29585

    $3,329/Mo
    1,598 sqft
    Highway access

    Vacant suite in Da Gullah Way with private restrooms, kitchen facilities, and adaptable space for retail or service uses.

    Monument signage  Building facade signage
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    Flex Space With Secured Yard
    Flex Space With Secured Yard

    4182 Tilly Swamp Rd., Conway, SC 29526

    $3,000/Mo
    2,000 sqft  2,000 sqft office  1,200 sqft warehouse
    Highway access

    Industrial outdoor storage and contractor yard with office, warehouse space, gated access, and proximity to major highways.

    Outdoor storage  Fenced yard  Secured gated access
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    Class A Medical Office Space
    Class A Medical Office Space

    655 Scholar Way, Summerville, SC 29486

    $37 SF/Yr
    12,000 sqft

    Class A medical/general office space in Nexton mixed-use development.

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