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    Lancaster County, SC Retail Space for Sale

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    Mixed-Use Investment Opportunity
    Updated: Oct 1, 2025
    Mixed-Use Investment Opportunity

    979-987 University Dr, Lancaster, SC

    $1,150,000
    20,606 sqft 2.15 AC lot
    ±1.81 acre parcel with mixed‑use income potential.
    Existing tenant‑occupied office, industrial, and retail spaces.
    Self‑storage facility with 48 units (±70% occupied) providing immediate income.
    Additional ±0.34 acre parcel included.
    ±11,664 SF dedicated to self‑storage.
    View details
    Downtown Mixed-Use Redevelopment Property
    Updated: Jun 11
    Downtown Mixed-Use Redevelopment Property

    210 S. White Street, Lancaster, SC 29720

    $760,000
    22,251 sqft
    1930s vintage commercial buildings in downtown Lancaster, currently vacant and in need of renovation
    Previously used as retail or office space, offering flexibility for mixed‑use redevelopment
    Location just off Highway 521, about 5 minutes from the intersection with Highway 9
    Vacancy context provided: retail vacancies reportedly at 3%, with general retail rental rates up 2.5% YoY and office up 1.8%
    Comprehensive plan notes these properties are within a municipality designation
    View details
    1930s Retail/Office Building Portfolio
    1930s Retail/Office Building Portfolio

    116 Arch Street, Lancaster, SC 29720

    $575,000
    29,444 sqft

    Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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    Retail Buildings For Sale
    Retail Buildings For Sale

    1317 Hwy 9 ByPass W, Lancaster, SC 29720

    $550,000
    2,175 sqft

    Two commercial buildings for sale in a growing area.

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    Downtown Mixed-Use Building for Renovation
    Downtown Mixed-Use Building for Renovation

    229 S. Main Street, Lancaster, SC 29720

    $275,000
    15,266 sqft

    Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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    Based on your search, we've compiled 73 Potential Opportunities for your consideration. Besides 5 Active listings in Lancaster County, SC, we suggest exploring several alternatives: similar 67 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime PUD-Zoned Land Opportunity
    Prime PUD-Zoned Land Opportunity

    3229 State Road 207, Elkton, FL 32033

    $1,599,000
    900 sqft 2.07 AC lot

    2.07 acres of PUD-zoned land in a growing corridor.

    View details

    Off-Market Properties in Lancaster County, SC

    Consider similar Off-Market properties in Lancaster County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1170 Hwy 9th W Byp
    RETAIL STORES (PERSONAL SERVICES)

    1170 Hwy 9th W Byp, Lancaster, SC 29720

    Value Estimation by Request
    4,160 sqft 70.00 AC lot
    View details
    Caston St
    RETAIL STORES (PERSONAL SERVICES)

    Caston St, Heath Springs, SC 29058

    Value Estimation by Request
    1,600 sqft 40.00 AC lot
    View details
    536 Echo Woods Dr
    RETAIL STORES (PERSONAL SERVICES)

    536 Echo Woods Dr, Lancaster, SC 29720

    Value Estimation by Request
    1,132 sqft 0.46 AC lot
    View details
    144 Marion St
    RETAIL STORES (PERSONAL SERVICES)

    144 Marion St, Kershaw, SC 29067-1444

    Value Estimation by Request
    2,990 sqft 25.00 AC lot
    View details
    243 Hampton St
    RETAIL STORES (PERSONAL SERVICES)

    243 Hampton St, Kershaw, SC 29067-1313

    Value Estimation by Request
    4,888 sqft 52.00 AC lot
    View details
    1897 Rocky Riv Rd
    RETAIL STORES (PERSONAL SERVICES)

    1897 Rocky Riv Rd, Lancaster, SC 29720-8925

    Value Estimation by Request
    2,624 sqft 0.59 AC lot
    View details
    1309 Hwy 9th W Byp
    RETAIL STORES (PERSONAL SERVICES)

    1309 Hwy 9th W Byp, Lancaster, SC 29720-4713

    Value Estimation by Request
    1,600 sqft 54.00 AC lot
    View details
    110 Main St
    RETAIL STORES (PERSONAL SERVICES)

    110 Main St, Heath Springs, SC 29058-9516

    Value Estimation by Request
    3,360 sqft 30.00 AC lot
    View details
    1755 Airport Rd
    RETAIL STORES (PERSONAL SERVICES)

    1755 Airport Rd, Lancaster, SC 29720-3896

    Value Estimation by Request
    8,520 sqft 1.50 AC lot
    View details
    1125 Hwy 9th W Byp
    RETAIL STORES (PERSONAL SERVICES)

    1125 Hwy 9th W Byp, Lancaster, SC 29720

    Value Estimation by Request
    8,400 sqft 60.00 AC lot
    View details
    Main St
    RETAIL STORES (PERSONAL SERVICES)

    Main St, Heath Springs, SC 29058

    Value Estimation by Request
    2,130 sqft 30.00 AC lot
    View details
    714 Market St
    RETAIL STORES (PERSONAL SERVICES)

    714 Market St, Lancaster, SC 29720-3666

    Value Estimation by Request
    13,984 sqft 1.97 AC lot
    View details
    167 Shop Rd
    RETAIL STORES (PERSONAL SERVICES)

    167 Shop Rd, Kershaw, SC 29067-2018

    Value Estimation by Request
    4,754 sqft 400.00 AC lot
    View details
    Old Monroe Camden Hwy
    RETAIL STORES (PERSONAL SERVICES)

    Old Monroe Camden Hwy, Lancaster, SC 29720

    Value Estimation by Request
    5,760 sqft 1.03 AC lot
    View details
    216 Brooklyn Ave
    RETAIL STORES (PERSONAL SERVICES)

    216 Brooklyn Ave, Lancaster, SC 29720

    Value Estimation by Request
    2,671 sqft 36.00 AC lot
    View details
    2663 Kershaw Camden Hwy
    RETAIL STORES (PERSONAL SERVICES)

    2663 Kershaw Camden Hwy, Lancaster, SC 29720-6854

    Value Estimation by Request
    10,395 sqft 0.91 AC lot
    View details
    1803 Great Fls Rd
    RETAIL STORES (PERSONAL SERVICES)

    1803 Great Fls Rd, Lancaster, SC 29720-0233

    Value Estimation by Request
    1,520 sqft 2.18 AC lot
    View details
    122 Hart St
    RETAIL STORES (PERSONAL SERVICES)

    122 Hart St, Kershaw, SC 29067-1436

    Value Estimation by Request
    14,076 sqft 118.00 AC lot
    View details
    Springdale Rd
    RETAIL STORES (PERSONAL SERVICES)

    Springdale Rd, Lancaster, SC 29720

    Value Estimation by Request
    3,600 sqft 232.00 AC lot
    View details

    Lancaster County, SC Retail Space Market Trends and Statistics

    Explore 72 retail space for sale in Lancaster County, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 89,742 square feet of properties for sale, with an estimated market value of $3,310,000.

    Sale prices for retail space in Lancaster County, SC start at $275,000, averaging $662,000, and reaching up to $1,150,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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