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    Florence County, SC Office Properties & Spaces for Sale

    12 results
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    Versatile Commercial Property Near Downtown
    $550,000
    67,518 SF

    Versatile Commercial Property Near Downtown

    121 Lawson St, Florence, SC 29501

    Office, showroom, and warehouse space near downtown Florence, SC.

    • Versatile commercial space with office, showroom, and warehouse areas under one roof.
    • Located less than one mile from Downtown Florence, SC.
    • Approximately 7,500 sq ft of heated and cooled office and showroom space with 9 offices and 3 showroom suites.
    • Zoned Light Industrial, allowing a wide range of permitted uses.
    • Multiple loading docks, delivery doors, and drive‑in doors for warehouse accessibility.
    Updated: Feb 16
    View details
    Industrial Buildings with Power & Access
    $199,000
    40,000 SF

    Industrial Buildings with Power & Access

    120 N Guerry St, Florence, SC 29501

    Two industrial buildings ideal for fabrication, automotive, or storage.

    • Two standalone industrial buildings offer flexibility for various uses.
    • Light Industrial zoning supports a wide range of commercial and industrial operations.
    • Brick building features approximately 20‑foot ceilings, three‑phase power, and three roll‑up doors.
    • Concrete block building includes 5,000 SF of interior space plus 2,000 SF of covered area and interior office space.
    • Ideal for fabrication, automotive uses, contractor operations, or storage.
    Updated: Mar 1
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    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    Office building with 7,517 square feet of space in Florence.

    1706 2Nd Loop Rd, Florence, SC 29501
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    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC 29560
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    McLeod Physician Associates For Sale
    Contact for pricing
    2,666 SF

    McLeod Physician Associates For Sale

    2,666 SF medical office in Florence, SC for sale.

    1540 American Dr, Florence, SC 29505
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    Medical Office Building Near MUSC
    Contact for pricing
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Ct, Florence, SC 29505
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    Downtown Florence Business Technology Center
    Contact for pricing
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.

    187 E Evans St, Florence, SC 29506
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    Updated Commercial Building with Showroom
    $1,600,000

    Updated Commercial Building with Showroom

    Updated 15,600 SF commercial building with showroom and loading docks.

    209 N Church St, Lake City, SC 29560
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    101 W Market St Office Building
    $150,000
    1,978 SF

    101 W Market St Office Building

    Timmonsville Office Space - $150k

    101 Market St, Timmonsville, SC 29161
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    Historic Downtown Florence Medical Office
    $1,350,000
    12,411 SF

    Historic Downtown Florence Medical Office

    12,411 SF Medical Office Building, $1.35M

    329 Irby St, Florence, SC 29501
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    Florence Office Building - $285K
    $285,000
    1,829 SF

    Florence Office Building - $285K

    1,829 SF Office, High Traffic Area

    2400 2Nd Loop Rd, Florence, SC 29501
    View details
    Based on your search, we've compiled 621 Potential Opportunities for your consideration. Besides 12 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 605 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 2Nd Loop Rd, Florence, SC 29501
    View details
    Florence Commercial Land For Sale
    $49,900
    0.17 Acres

    Florence Commercial Land For Sale

    B-6 zoned property with commercial and redevelopment options.

    720 S Barringer St, Florence, SC 29506
    View details
    Prime Commercial Development Site
    $980,000
    4.76 Acres

    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Dr, Florence, SC 29501
    View details
    Commercial Lot on Darlington Street
    $31,000
    0.19 Acres

    Commercial Lot on Darlington Street

    Commercial lot with frontage on East Darlington Street, Florence, SC.

    East Darlington St, Florence, SC 29506
    View details

    Explore Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2601 Tv Rd

    2601 Tv Rd

    OFFICE BUILDING • 2,800 SF
    Value Estimation by Request
    2601 Tv Rd, Florence, SC 29501-0703
    View details
    255 Warley St

    255 Warley St

    OFFICE BUILDING • 3,590 SF
    Value Estimation by Request
    255 Warley St, Florence, SC 29501-4444
    View details
    531 Evans St

    531 Evans St

    OFFICE BUILDING • 1,948 SF
    Value Estimation by Request
    531 Evans St, Florence, SC 29501-3407
    View details
    1825 Palmetto St

    1825 Palmetto St

    MEDICAL BUILDING • 11,322 SF
    Value Estimation by Request
    1825 Palmetto St, Florence, SC 29501-4137
    View details
    1250 Celebration Blvd

    1250 Celebration Blvd

    OFFICE BUILDING • 1,524 SF
    Value Estimation by Request
    1250 Celebration Blvd, Florence, SC 29501-5498
    View details
    204 Cheves St

    204 Cheves St

    MEDICAL BUILDING • 11,545 SF
    Value Estimation by Request
    204 Cheves St, Florence, SC 29506-2604
    View details
    217 3rd Ave

    217 3rd Ave

    MEDICAL BUILDING • 1,800 SF
    Value Estimation by Request
    217 3rd Ave, Pamplico, SC 29583-3938
    View details
    110 Trade St

    110 Trade St

    OFFICE BUILDING • 360 SF
    Value Estimation by Request
    110 Trade St, Pamplico, SC 29583
    View details
    140 Beulah Rd

    140 Beulah Rd

    OFFICE BUILDING • 2,011 SF
    Value Estimation by Request
    140 Beulah Rd, Lake City, SC 29560-7915
    View details
    117 12th Sauls St

    117 12th Sauls St

    OFFICE BUILDING • 1,978 SF
    Value Estimation by Request
    117 12th Sauls St, Lake City, SC 29560-2630
    View details
    119 Sauls St

    119 Sauls St

    OFFICE BUILDING • 1,827 SF
    Value Estimation by Request
    119 Sauls St, Lake City, SC 29560-2630
    View details
    831 Georgetown Hwy

    831 Georgetown Hwy

    OFFICE BUILDING • 432 SF
    Value Estimation by Request
    831 Georgetown Hwy, Johnsonville, SC 29555-8041
    View details

    Florence County, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 617 office properties & spaces for sale in Florence County, SC, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 18,240,647 square feet of properties for sale, with an estimated market value of $147,909,000.

    Sale prices for office spaces in Florence County, SC start at $50,000, averaging $577,769, and reaching up to $15,640,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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