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    Florence County, SC Office Properties & Spaces for Sale

    10 results
    Notify Me
    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    1706 2Nd Loop Rd, Florence, SC 29501

    Office building with 7,517 square feet of space in Florence.

    • Handicap access: accessible approach with ramp.
    • Features office(s) and reception area.
    • Kitchen facility available.
    • Private restrooms.
    • Central heating and central air.
    Last Update: Oct 24
    View details
    Pamplico Highway Commercial Opportunity
    $229,900
    0.80 Acres

    Pamplico Highway Commercial Opportunity

    1424 Pamplico Hwy, Florence, SC 29505

    Commercial lot on heavily traveled Pamplico Highway with multiple driveways.

    • High‑traffic location on Pamplico Highway
    • Four driveways providing easy access
    • Suitable for retail or commercial development
    • Existing house usable as an office
    • Road frontage
    Last Update: Aug 14
    View details
    101 W Market St Office Building
    $150,000
    1,978 SF

    101 W Market St Office Building

    Timmonsville Office Space - $150k
    101 Market St, Timmonsville, SC 29161
    View details
    Historic Downtown Florence Medical Office
    $1,350,000
    12,411 SF

    Historic Downtown Florence Medical Office

    12,411 SF Medical Office Building, $1.35M
    329 Irby St, Florence, SC 29501
    View details
    Florence Office Building - $285K
    $285,000
    1,829 SF

    Florence Office Building - $285K

    1,829 SF Office, High Traffic Area
    2400 2Nd Loop Rd, Florence, SC 29501
    View details
    Medical Office Building Near MUSC
    $2,200,000
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.
    1929 Mountain Laurel Ct, Florence, SC 29505
    View details
    Historic Mixed-Use Building in Florence
    $3,000,000
    13 SF

    Historic Mixed-Use Building in Florence

    16,000 sq ft historic building in Downtown Florence for sale.
    248 W Evans St Florence, Florence, SC 29501
    View details
    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.
    215 John St, Lake City, SC 29560
    View details
    Downtown Florence Business Technology Center
    $12,000,000
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.
    187 E Evans St, Florence, SC 29506
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF

    McLeod Physician Associates For Sale

    2,666 SF medical office in Florence, SC for sale.
    1540 American Dr, Florence, SC 29505
    View details
    Based on your search, we've compiled 618 Potential Opportunities for your consideration. Besides 10 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 605 Off-Market properties to explore as potential leads, plus 3 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.
    1714 2Nd Loop Rd, Florence, SC 29501
    View details
    Florence Commercial Land For Sale
    $49,900
    0.17 Acres

    Florence Commercial Land For Sale

    Versatile B-6 zoned property with commercial and redevelopment potential.
    720 S Barringer St, Florence, SC 29506
    View details
    Prime Commercial Lot in Florence
    $980,000
    4.76 Acres

    Prime Commercial Lot in Florence

    4.76 acre commercial lot in a high-traffic Florence location.
    917 S Cashua Dr, Florence, SC 29501
    View details

    Explore Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1092 Church St

    1092 Church St

    Flex space
    Value Estimation by Request
    1092 Church St, Florence, SC 29506
    View details
    113 Main St

    113 Main St

    Individual retail properties • 7,830 SF
    Value Estimation by Request
    113 Main St, Lake City, SC 29560
    View details
    650 Pamplico Hwy

    650 Pamplico Hwy

    Medical offices • 2,500 SF
    Value Estimation by Request
    650 Pamplico Hwy, Florence, SC 29505
    View details
    211 Pamplico Hwy

    211 Pamplico Hwy

    Office Properties & Spaces • 9,600 SF
    Value Estimation by Request
    211 Pamplico Hwy, Florence, SC 29505
    View details
    102 Sebrell St

    102 Sebrell St

    Office Properties & Spaces • 1,000 SF
    Value Estimation by Request
    102 Sebrell St, Florence, SC 29505
    View details
    1947 Hoffmeyer Rd

    1947 Hoffmeyer Rd

    Medical offices
    Value Estimation by Request
    1947 Hoffmeyer Rd, Florence, SC 29501
    View details
    400 Evans St

    400 Evans St

    Office Properties & Spaces • 2,400 SF
    Value Estimation by Request
    400 Evans St, Florence, SC 29501
    View details
    1800 2Nd Loop Rd

    1800 2Nd Loop Rd

    Office Properties & Spaces • 7,900 SF
    Value Estimation by Request
    1800 2Nd Loop Rd, Florence, SC 29501
    View details
    609 2Nd Loop Rd

    609 2Nd Loop Rd

    Medical offices • 3,600 SF
    Value Estimation by Request
    609 2Nd Loop Rd, Florence, SC 29505
    View details
    1224 Broughton Blvd

    1224 Broughton Blvd

    Flex space • 1,250 SF
    Value Estimation by Request
    1224 Broughton Blvd, Florence, SC 29501
    View details
    215 3rd Loop Rd

    215 3rd Loop Rd

    OFFICE BUILDING • 10,709 SF
    Value Estimation by Request
    215 3rd Loop Rd, Florence, SC 29505-4717
    View details
    151 Evans St

    151 Evans St

    OFFICE BUILDING • 14,829 SF
    Value Estimation by Request
    151 Evans St, Florence, SC 29501-3425
    View details
    1714 Gregg Ave

    1714 Gregg Ave

    MEDICAL BUILDING • 4,969 SF
    Value Estimation by Request
    1714 Gregg Ave, Florence, SC 29501-4120
    View details
    2200 Irby St

    2200 Irby St

    MEDICAL BUILDING • 5,996 SF
    Value Estimation
    $3,130,000
    2200 Irby St, Florence, SC 29505-3423
    View details

    Florence County, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 614 office properties & spaces for sale in Florence County, SC, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 18,175,307 square feet of properties for sale, with an estimated market value of $147,509,900.

    Prices for office spaces in Florence County, SC start at $50,000, averaging $578,470, and reaching up to $15,640,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Browse Office Properties & Spaces for Sale Near Florence, SC

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