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    Charleston County, SC Office Spaces for Lease

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    169 properties
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    Renovated Class A Office Building
    Renovated Class A Office Building

    4055 Faber Place Drive, North Charleston, SC 29405

    $30 SF/Yr
    1,947 sqft

    Three-story office building with high-end finishes, available April 2026.

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    Class A Medical Office Building
    Class A Medical Office Building

    1200 Innovation Way, Mount Pleasant, SC 29466

    $28 SF/Yr
    14,084 sqft

    Renovated medical/office building with ample parking in Mt. Pleasant.

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    Class A Office Space Available
    Class A Office Space Available

    4401 Leeds Avenue, North Charleston, SC 29405

    $34.50 SF/Yr
    8,452 sqft

    Four-story, 102,024 SF Class A office building for lease.

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    Class A Office Space
    Class A Office Space

    100 Calhoun Street, Charleston, SC 29401

    $43 SF/Yr
    9,675 sqft

    Multi-tenant office building in Charleston's Historic District.

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    Historic Office Suite with Rooftop Patio
    Historic Office Suite with Rooftop Patio

    81 Hasell Street, Charleston, SC 29401

    $2,300/Mo

    Character-rich workspace with an open plan, original architectural details, and shared outdoor amenity access.

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    Park Circle Freestanding Retail Building
    Park Circle Freestanding Retail Building

    1086 East Montague Avenue, North Charleston, SC 29405

    $35 SF/Yr
    1,800 sqft

    Freestanding building in Park Circle, ideal for retail or office.

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    Upper King Street Office Space
    Upper King Street Office Space

    463 King Street, Charleston, SC 29403

    $34 SF/Yr
    3,204 sqft

    Office space for rent in Charleston's Upper King District.

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    Furnished Office Building Sublease Opportunity
    Furnished Office Building Sublease Opportunity

    125 Fairchild Street, Charleston, SC, USA, Charleston, SC 29492

    $24 SF/Yr
    78,394 sqft

    Well-appointed, fully furnished office building available for sublease.

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    Flexible Commercial Building
    Flexible Commercial Building

    1524 Ashley River Rd, Charleston, SC 29407

    $4,500/Mo

    Commercial building with adaptable space and road frontage near downtown Charleston and I-526.

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    Class A Office Downtown Charleston
    Class A Office Downtown Charleston

    525 East Bay Street, Charleston, SC 29403

    $39 SF/Yr
    14,515 sqft

    Class A office space for rent in downtown Charleston.

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    Downtown Charleston
    Downtown Charleston

    170 Floors, Charleston, SC 29401

    16 available spaces from 11 to 2,055 sqft
    $129-$24,659/Mo per office

    Flexible workspace in Downtown Charleston. Book a tour & get info

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    Renovated Industrial Space Available
    Renovated Industrial Space Available

    7391 Pepperdam Avenue, North Charleston, SC 29418

    $10 SF/Yr
    96,811 sqft

    Recently renovated industrial suites available for lease in North Charleston.

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    Retail Office Restaurant Space
    Retail Office Restaurant Space

    7027 Dorchester Rd, North Charleston, SC 29418

    $1,500/Mo

    Leasable commercial space on Dorchester Road with modern amenities and ample parking for customers.

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    Downtown Charleston Office Space
    Downtown Charleston Office Space

    11 Isabella St Suite A, Charleston, SC 29403

    $29 SF/Yr
    1,650 sqft

    Office space for rent in Charleston's growing Upper Peninsula.

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    Medical Office in Mt. Pleasant
    Medical Office in Mt. Pleasant

    1300 Hospital Dr, Mount Pleasant, SC 29464

    $34 SF/Yr
    60,809 sqft

    Medical office space available for sublease in Mt. Pleasant.

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    West Ashley Multi-Tenant Office Property
    West Ashley Multi-Tenant Office Property

    1460 Tobias Gadson Boulevard, Charleston, SC 29407

    $25 SF/Yr
    38,510 sqft

    Multi-tenant office property in West Ashley with suites available for lease.

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    Historic Downtown Office Suite
    Historic Downtown Office Suite

    76 Spring St Ste A, Charleston, SC 29403

    $5,200/Mo

    Historic office suite with high ceilings, original hardwood floors, and dedicated balcony access in downtown Charleston.

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    Charleston Peninsula Office Space
    Charleston Peninsula Office Space

    1501 King Street Extension, Charleston, SC 29405

    $36.50 SF/Yr
    7,390 sqft

    Cool office space in pioneering mixed-use redevelopment on Charleston Peninsula.

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    Heavy Industrial Flex Space
    Heavy Industrial Flex Space

    2025 Austin Ave, Charleston, SC 29405

    Contact for pricing
    18,107 sqft 6.76 AC lot

    Fenced outdoor storage, warehouse, shop, and office components support industrial and fleet operations.

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    Downtown Office Suites
    Downtown Office Suites

    177 Meeting St, Charleston, SC 29401

    Contact for pricing
    6,425 sqft

    Office space available in a central downtown building with established retail and service tenants nearby.

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    Industrial Storage Parcel with Warehouse
    Industrial Storage Parcel with Warehouse

    2026 Meeting Street Rd, Charleston, SC 29405

    $17,500/Mo
    4,000 sqft 2.00 AC lot

    Cleared, fenced outdoor storage parcel with a 4,000 SF warehouse, grade-level doors, and office space.

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    Freestanding Warehouse Flex Building
    Freestanding Warehouse Flex Building

    2960 Rivers Avenue, North Charleston, SC 29405

    Contact for pricing
    5,000 sqft 0.22 AC lot

    Freestanding warehouse flex with office, rollup doors, and a laydown yard on a hard-corner for strong visibility.

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    Renovated Second-Floor Office Suite
    Renovated Second-Floor Office Suite

    516 King Street, Charleston, SC 29403

    Contact for pricing
    4,100 sqft

    Completely renovated second-floor suite with new HVAC, restored hardwood floors, and abundant natural light for walkable access.

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    Private Office Suite with Kitchenette
    Private Office Suite with Kitchenette

    277 Meeting Street, Charleston, SC 29401

    Contact for pricing
    1,547 sqft

    Private office suite with dedicated collaboration space, kitchenette, and optional off-street parking.

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