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    Charleston County, SC Office Spaces for Lease

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    169 properties
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    Medical Office Suite
    Medical Office Suite

    3210 Landmark Drive, North Charleston, SC 29418

    Contact for pricing
    1,880 sqft

    Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

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    Flex Warehouse with Office
    Flex Warehouse with Office

    1070 Jenkins Rd Ste 101, Charleston, SC 29407

    Contact for pricing
    1,500 sqft

    Flex/warehouse suite with climate-controlled warehouse access via glass double doors and dedicated office with private restroom.

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    Turnkey Office Suites
    Turnkey Office Suites

    1180 Sam Rittenberg Blvd, Charleston, SC 29407

    Contact for pricing
    2,209 sqft

    Turnkey office suites with newly renovated common areas and landscaping, offered for immediate occupancy.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    268 W Coleman Blvd, Mount Pleasant, SC 29464

    Contact for pricing
    3,166 sqft

    Move-in ready second-floor office suite with open bullpen, perimeter offices, conference room, and eat-in kitchen.

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    Open Office Suite With Private Rooms
    Open Office Suite With Private Rooms

    100 Cool Blow Street Suite 122, Charleston, SC 29403

    Contact for pricing
    1,000 sqft

    First-floor workspace offers natural light, shared collaboration space, private rooms, storage, and a dedicated restroom.

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    Flex Space with Mezzanine Storage
    Flex Space with Mezzanine Storage

    2612 Larch Lane, Suite 110, Mount Pleasant, SC 29466

    Contact for pricing
    1,900 sqft

    Modern commercial suite pairs finished office areas with warehouse space, rear loading, and additional storage above.

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    Flex Warehouse Office Suite
    Flex Warehouse Office Suite

    2612 Larch Lane, Suite 103, Mount Pleasant, SC 29466

    Contact for pricing
    1,500 sqft

    Suite 103 offers two private offices, reception, restroom, and warehouse space with a rear roll-up door.

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    Historic Office/Retail Space
    Historic Office/Retail Space

    356 King Street, Charleston, SC 29401

    Contact for pricing
    1,637 sqft

    Second and third floor suite in a historic building on a prime retail corridor.

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    Brick Office Suite with Six Offices
    Brick Office Suite with Six Offices

    3301 Salterbeck St, Mount Pleasant, SC 29466

    Contact for pricing
    1,652 sqft

    Freestanding professional suite offers private offices, reception, support rooms, and dedicated building parking.

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    Two-Story Freestanding Office Building
    Two-Story Freestanding Office Building

    2125 Charlie Hall Blvd, Charleston, SC 29414

    Contact for pricing
    13,113 sqft

    Entire first floor is available in a centrally located, medically oriented freestanding office building with ample parking.

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    Flex Suite with Rear Roll-Up Door
    Flex Suite with Rear Roll-Up Door

    2612 Larch Lane, Suite 107, Mount Pleasant, SC 29466

    Contact for pricing
    1,900 sqft

    Modern flex space includes private offices, reception, restroom, and a rear roll-up door.

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    Downstairs Office Unit
    Downstairs Office Unit

    781 Meeting Street, Charleston, SC 29403

    Contact for pricing
    924 sqft

    Ground-level office and retail space with shared rear parking near shops and restaurants.

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    Dental-To-Medical Office Suite
    Dental-To-Medical Office Suite

    1065-C Johnnie Dodds Blvd, Mount Pleasant, SC 29464

    Contact for pricing
    1,500 sqft

    Turn-key office currently set up for dental use, positioned across from a major hospital with convenient highway access.

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    Freestanding Flex Building
    Freestanding Flex Building

    3821 W Montague Ave, North Charleston, SC 29418

    Contact for pricing
    2,347 sqft 0.34 AC lot

    Office and warehouse configuration with fenced grounds and roll-up access.

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    Professional Office Space
    Professional Office Space

    3 Oak Forest Dr, Charleston, SC 29407

    Contact for pricing
    1,000 sqft

    Professional office suite includes a reception area, four offices, kitchenette, two bathrooms, and attic/office space.

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    Flex Space with Office and Warehouse
    Flex Space with Office and Warehouse

    3216 Industry Dr, North Charleston, SC 29418

    Contact for pricing
    10,500 sqft 3.49 AC lot

    The property combines loading functionality with parking for industrial operations.

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    Office Space Available For Rent
    Office Space Available For Rent

    2387 Clements Ferry Road, Charleston, SC 29492

    $26.95 SF/Yr
    33,492 sqft

    Office space available for lease with 33492 square feet.

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    Flex Space with Laydown Yard
    Flex Space with Laydown Yard

    4510 Rivers Ave, North Charleston, SC 29405

    Contact for pricing
    1,440 sqft

    Graveled, fenced laydown yard with secure tractor-trailer parking and office space split across multiple trailers.

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    Office Suite with Parking
    Office Suite with Parking

    845 Lowcountry Blvd, Mount Pleasant, SC 29464

    Contact for pricing
    215 sqft

    Office suite includes free on-site parking, a kitchenette, and shared conference room access.

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    Charleston Office Building with Harbor Views
    Charleston Office Building with Harbor Views

    2 Cumberland St, Charleston, SC 29401

    $22 SF/Yr

    Renovated office suites with harbor views in historic Charleston.

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    Downtown Retail/Office Suite
    Downtown Retail/Office Suite

    354 King St, Charleston, SC 29401

    Contact for pricing
    3,000 sqft

    Second-floor space with high ceilings, large windows, and nearby parking, available for retail or office use.

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    Two-Office First-Floor Suite
    Two-Office First-Floor Suite

    825 Lowcountry Boulevard, Mount Pleasant, SC 29464

    Contact for pricing
    150 sqft

    Suite 103 provides a compact office configuration within a business center setting.

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    First-Floor Office Suite
    First-Floor Office Suite

    48 Society Street, Charleston, SC 29401

    Contact for pricing
    676 sqft

    Recently renovated first-floor office with shared restroom and two off-street parking spaces; utilities/taxes/insurance included.

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    Office Unit With Sublease Term
    Office Unit With Sublease Term

    537 Folly Rd, Charleston, SC 29412

    Contact for pricing
    2,087 sqft

    Professional office space offered through a two-year sublease beginning July 1, 2025.

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