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Lee County, FL Office Spaces for Lease

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243 properties
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Prominent Location in Cape Coral
Prominent Location in Cape Coral

4426 SE 16Th Pl, Cape Coral, FL 33904

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1,272 sqft

Free standing Office building

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Prominent Location in Cape Coral
Prominent Location in Cape Coral

4426 SE 16Th Pl, Cape Coral, FL 33904

Contact for pricing
1,272 sqft

Free standing Office building

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Estero Office Space Available
Estero Office Space Available

8000 Health Center Blvd, Estero, FL

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1,890 sqft 6.76 AC lot

Office space available for lease in Estero, Florida.

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Two-Story Medical Office Suites
Two-Story Medical Office Suites

2534 Santa Barbara Boulevard South, Cape Coral, FL 33904

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Two-story office building offering turnkey first-floor medical space and second-floor executive office/lab space.

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Bonita Springs Office Space Available
Bonita Springs Office Space Available

24031 S Tamiami Trail, Bonita Springs, FL

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12,134 sqft 0.40 AC lot

Office space available for lease in Bonita Springs, Florida.

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Medical Office Space in Burks Plaza
Medical Office Space in Burks Plaza

13195 Metro PKWY, Fort Myers, FL 33966

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Established medical office setting near Lee Health facilities and major Fort Myers roadways.

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Fort Myers Office Space Available
Fort Myers Office Space Available

1825 COLONIAL Blvd, Fort Myers, FL 33907

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0.51 AC lot

Move-in-ready office space in a convenient Fort Myers location.

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Office Suite with Private Offices
Office Suite with Private Offices

3443 Hancock Bridge Parkway, North Fort Myers, FL 33903

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Office space includes a waiting area, reception, restrooms, breakroom, and private offices or a conference room.

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Office Unit with Storage
Office Unit with Storage

333 PARK Avenue, Boca Grande, FL 33921

$4,775/Mo
944 sqft 0.34 AC lot

C-2-zoned office space with a flexible work area, private meeting room, and supplemental storage.

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Well-Maintained Office Building
Well-Maintained Office Building

6360 Presidential Court, Fort Myers, FL 33919

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Well-maintained office building with a new roof and new A/C, positioned on a high-traffic corridor.

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Accessible Fort Myers Office Space
Accessible Fort Myers Office Space

12761 World Plaza Ln Ste 2, Fort Myers, FL 33907

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Office space in accessible Fort Myers location, ready August 2025.

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Renovated Office Near Downtown
Renovated Office Near Downtown

3949 Evans Ave, Fort Myers, FL 33901

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Recently renovated lockable office space with shared amenities for rent.

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Office Space with US41 Frontage
Office Space with US41 Frontage

12381 S Cleveland Ave, Fort Myers, FL 33907

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4,162 sqft

Office space in Fort Myers with frontage on US41 and access to major regional routes.

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Office Space For Rent
Office Space For Rent

9371 Cypress Lake Dr, Fort Myers, FL

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2,264 sqft 2.90 AC lot

Office space available for lease in Fort Myers, Florida.

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Flexible Medical Office Space
Flexible Medical Office Space

27960 Bonita Grande Drive, Bonita Springs, FL 34135

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Flexible medical office and office space availability within a mixed-use lifestyle center in Bonita Springs.

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Renovated Ground-Floor Medical Office
Renovated Ground-Floor Medical Office

14090 Metropolis Avenue, Fort Myers, FL 33912

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0.25 AC lot

Ground-floor suite includes exam rooms, sinks, reception, private office, break room, and private bathroom.

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Office Unit at Signalized Intersection
Office Unit at Signalized Intersection

18070 S Tamiami Trail, Fort Myers, FL 33908

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0.71 AC lot

C1A-zoned office space in a plaza with medical and professional office tenants.

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Fort Myers Office Space Available
Fort Myers Office Space Available

12751 Westlinks Dr, Fort Myers, FL

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8,320 sqft 7.01 AC lot

8,320 SF office space for rent in Fort Myers.

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2328 Hancock Bridge Pkwy, Cape Coral, FL 33990
2328 Hancock Bridge Pkwy, Cape Coral, FL 33990

2328 Hancock Bridge Pkwy, Cape Coral, FL 33990

$17.50 SF/Yr

Office space for lease with pylon signage and parking.

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2328 Hancock Bridge Pkwy, Cape Coral, FL
2328 Hancock Bridge Pkwy, Cape Coral, FL

2328 Hancock Bridge Pkwy, Cape Coral, FL 33990

$17.50 SF/Yr

Office space for lease with pylon signage and parking.

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2328 Hancock Bridge Pkwy, Cape Coral, FL
2328 Hancock Bridge Pkwy, Cape Coral, FL

2328 Hancock Bridge Pkwy, Cape Coral, FL 33990

$17.50 SF/Yr

Office space for lease with pylon signage and parking.

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Second-Generation Dental Office Unit
Second-Generation Dental Office Unit

12691 New Brittany Boulevard, Fort Myers, FL 33907

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Office space configured for dental use at New Brittany Boulevard in Fort Myers.

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Colonial Boulevard Office Space Available
Colonial Boulevard Office Space Available

3800 Colonial Blvd, Fort Myers, FL

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1,775 sqft 1.36 AC lot

Office space for rent with monument signage and covered parking.

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Two-Story Office Suites with Elevator
Two-Story Office Suites with Elevator

3820 COLONIAL Boulevard, Fort Myers, FL 33966

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1.41 AC lot

Office and salon suites in a two-story building with elevator access and surface parking.

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