Lee County, FL Mixed-use properties for Rent & Lease

Updated: Aug 5, 2025

Retail Space in Lifestyle Center

27800 Bonita Grande Dr, Bonita Springs, FL 34135

Contact for pricing

1,500 sqft

1,625‑square‑foot retail space available for lease
Mixed‑use center with approximately 200,000± SF of restaurant and retail space
Development includes 400 luxury apartments and a 165‑key hotel
1,300 linear feet of frontage along Bonita Beach Road
First lighted intersection east of I‑75, near Exit 118

View details

Updated: Feb 14, 2025

Retail and Office Center

13451 Mcgregor Blvd, Fort Myers, FL 33919

Contact for pricing

1,179 sqft

Prominent retail and office center at the intersection of McGregor Blvd. and Cypress Lake Dr.
Tenant mix includes long‑term tenants Prawnbroker and Blue Sushi.
Center includes upscale shops and restaurants.
Ample parking on‑site for customer and tenant access.
Retail and office center set in a park‑like setting.

View details

Alico Commercial Park7916 Drew Cir

7916 Drew Cir, Fort Myers, FL 33967, Fort Myers, FL 33967

$14.50 SF/Yr

26,611 SF of 4-Star Industrial Space Available in Fort Myers, FL 33967

View details

Office, Retail, and Warehouse Units

1939 Park Meadows Dr, Fort Myers, FL 33907

Contact for pricing

1,200 sqft

Office, retail, and warehouse units available for lease.

View details

Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 4 Active listings in Lee County, FL, we suggest exploring alternatives. Similar 45 Properties for Sales.

Similar Spaces for Sale in Lee County, FL

Consider Similar Space for Sale. We found 45 Spaces matching your search parameters.

Multi-Tenant Mixed-Use Building

50 Mildred Dr, Fort Myers, FL 33901

$800,000

5,835 sqft 0.38 AC lot

Commercial-intensive zoning and Mildred Drive access support varied retail, office, flex, and trade-oriented uses.

View details

Two-Story Mixed-Use Property

3724 Del Prado Blvd S, Cape Coral, FL 33904

$2,195,000

6,062 sqft

Freestanding commercial building with an operating restaurant, three service-retail suites, separate entrances, and on-site parking.

View details

Office, Retail & Flex Portfolio

1328 Lafayette St & 1323-1325, 1403 Miramar St, Cape Coral, FL 33904

$3,350,000

14,893 sqft

The assemblage combines adaptable buildings with conditioned office and warehouse areas and roll-up door access.

View details

Renovated Commercial Property on Fowler Street

2730 Fowler St, Fort Myers, FL 33901

$999,000

6,200 sqft 0.46 AC lot

Fully renovated commercial building with flexible space in Fort Myers.

View details

Prime Mixed-Use Development Opportunity

2915 Estero Boulevard, Fort Myers Beach, FL 33931

$1,095,000

4,748 sqft 0.11 AC lot

Cleared lot on Estero Blvd, steps from the Gulf.

View details

Mixed-Use Property with Residential Units

2251 GRAND Avenue, Fort Myers, FL 33901

$1,200,000

4,688 sqft 0.15 AC lot

Two renovated upstairs residences complement flexible ground-floor commercial space.

View details

Waterfront Mixed-Use Property

3269 Stringfellow Road, St James City, FL 33956

$625,000

0.30 AC lot

C-1-zoned property combines office/shop space with a two-bedroom apartment and canal access.

View details

Storefront Building with Bakery

1615 Se 47th Ter, Cape Coral, FL 33904

$1,072,000

3,634 sqft

Flexible SC-zoned commercial building with an existing bakery occupant and adaptable space for multiple business configurations.

View details

Shopping Center with Pylon Signage

12709-12731 McGregor Blvd, Fort Myers, FL 33919

$4,970,000

3.72 AC lot

Neighborhood center with access from College Pkwy and McGregor Blvd, parking, landscaping, and a varied commercial tenant mix.

View details

Three-Parcel Mixed-Use Assemblage

885 SE 47th Ter, Cape Coral, FL 33904

$3,550,000

0.75 AC lot

Two occupied commercial buildings and a vacant parcel combine existing NNN tenancy with options for future site planning.

View details

Waterfront Mixed-Use Property

St James City, FL 33956

$625,000

0.30 AC lot

Office and shop space adjoins a two-bedroom apartment, with a detached garage and canal access.

View details

Commercial Mixed-Use Assemblage

13160, 13170, 13180 & 13192 North Cleveland Avenue, North Fort Myers, FL 33903

$7,000,000

35,935 sqft

Four parcels combine existing retail and commercial improvements under CG, C-1A, and C-2 zoning.

View details

Mixed-Use Duplex with Commercial Space

2826 Santa Barbara Boulevard, Cape Coral, FL 33914

$429,000

2,406 sqft

MR zoning supports a live-work arrangement with commercial and residential components.

View details

Two-Story Mixed-Use Building

19011 San Carlos Boulevard, Fort Myers Beach, FL 33931

$1,075,000

0.20 AC lot

Freestanding commercial property with three upstairs apartments, shared laundry, storage areas, and a ground-level space requiring refurbishment.

View details

Commercial Land with Boulevard Exposure

1698 Estero Boulevard, Fort Myers Beach, FL 33931

$1,300,000

0.11 AC lot

Commercial land along Fort Myers Beach’s primary corridor, near Gulf beaches, dining, retail, lodging, and entertainment.

View details

Mixed-Use Commercial Property

16641 San Carlos Boulevard, Fort Myers, FL 33908

Contact for pricing

5,965 sqft 1.41 AC lot

Dual commercial zoning supports office, retail, restaurant, and service-oriented uses.

View details

Mixed-Use Property with Lake Views

2430 Palm Ridge Road, Sanibel, FL 33957

$2,989,000

0.99 AC lot

Three buildings combine leased commercial suites with remodeled apartments and residential outlooks over the lake.

View details

Commercial Sale

1165-1161 Estero Blvd, Fort Myers Beach, FL 33931

$3,600,000

5,568 sqft 0.16 AC lot

Mixed-use properties · 5,568 SF

View details

Two-Story Mixed-Use Building

917 SE 47th Terrace, Cape Coral, FL 33904

$2,100,000

0.14 AC lot

Flexible commercial building with event, office, classroom, kitchen, and storage areas across two separately accessible levels.

View details

Cape Coral Mixed-Use Opportunity

862 Lafayette St, Cape Coral, FL 33904

$2,970,000

17,564 sqft

Two-story, 17,500+ sq ft building in downtown Cape Coral.

View details

Lee County, FL Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in Lee County, FL with 4 listings featured on our commercial real estate exchange. The current inventory includes 3,879 square feet of properties with an estimated lease value of $14.50.

Estimated lease rates for Mixed-use properties in Lee County, FL average $14.50 SF/Yr.

Featured Lee County Real Estate Agencies

Realmo connects you with licensed Lee County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Priceless Realty

1425 Del Prado Blvd Cape Coral, FL 33990

Phone: 12397707121

www.pricelessrealty.com

Starlink Realty

1567 Hayley Lane, Suite 205 Fort Myers, FL 33907

Phone: 12396937263

www.starlinkrealty.com

Jones & Co. Realty

9403 Cypress Lake Dr. Suite 3 Fort Myers, FL 33919

Phone: 12394155881

Lee County, FL Mixed-use Properties for Lease

27800 Bonita Grande Dr, Bonita Springs, FL 34135

13451 Mcgregor Blvd, Fort Myers, FL 33919

7916 Drew Cir, Fort Myers, FL 33967, Fort Myers, FL 33967

1939 Park Meadows Dr, Fort Myers, FL 33907