Lee County, FL Mixed-use Properties for Lease

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Prime Commercial Space on College

8140 College Parkway, Fort Myers, FL 33919

Commercial space for lease in Fort Myers with excellent accessibility.

Prime location on College Parkway with high traffic count (39,000 vehicles per day).
Excellent accessibility to major roads and highways including U.S. Highway 41 and I‑75.
Versatile floor plans and customizable layouts suitable for office, retail, or mixed‑use.
Ample parking for tenants and clients.
Modern and attractive architectural design.

Updated: Nov 27, 2025

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$30 SF/Yr

40,000 SF

Mixed-Use Development in Fort Myers

1380-1400 Colonial Blvd, Fort Myers, FL 33907

Mixed-use development with retail, office, and medical spaces for lease.

Premier mixed‑use development with retail, medical, office, multifamily, and hotel components.
Located at the high‑traffic intersection of Colonial Blvd. and Summerlin Rd. in Fort Myers.
Flexible floor plans and build‑to‑suit options available for retail, medical, and office spaces.
High‑demand market with over $2 billion in consumer spending within a 5‑mile radius.
New, Class A medical office buildings with convenient access to major healthcare systems.

Updated: Feb 10, 2025

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Corner Showroom/Retail/Office/Warehouse Space

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2,123 SF

Corner Showroom/Retail/Office/Warehouse Space

Corner unit suitable for showroom, retail, office, or warehouse.

28360 Old 41 Rd, Bonita Springs, FL 34135

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$14 SF/Yr

Alico Commercial Park7916 Drew Cir

26,611 SF of 4-Star Industrial Space Available in Fort Myers, FL 33967

7916 Drew Cir, Fort Myers, FL 33967, Fort Myers, FL 33967

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Mixed-Use Property Available

Mixed-use property available for sale or lease.

12155 Metro Pkwy, Fort Myers, FL 33966

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$12 SF/Yr

1,200 SF

Office, Retail, and Warehouse Units

Office, retail, and warehouse units available for lease.

1939 Park Meadows Dr, Fort Myers, FL 33907

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Based on your search, we've compiled 53 Potential Opportunities for your consideration. Besides 6 Active listings in Lee County, FL, we suggest exploring alternatives. Similar 43 Properties for Sales.

Similar Spaces for Sale in Lee County, FL

Consider Similar Space for Sale. We found 43 Spaces matching your search parameters.

Versatile Commercial Building in Cape Coral

$2,400,000

8,600 SF

Versatile Commercial Building in Cape Coral

Two-story building in downtown Cape Coral suitable for various uses.

917 SE 47th Terrace, Cape Coral, FL 33904

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$885,000

0.70 Acres

Versatile Property in Fort Myers

Adaptable commercial property with income potential in Fort Myers, FL.

3145 Royalston Avenue, Fort Myers, FL 33916

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$1,200,000

4,688 SF

Mixed-Use Property with Fenced Parking

Three distinct income spaces upstairs residential and ground-floor studio, supported by dedicated fenced parking for tenants and visitors.

2251 GRAND AVENUE, Fort Myers, FL 33901

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$2,700,000

0.63 Acres

Sanibel Commercial Building For Sale

Income-producing commercial building in Sanibel's Central Business District.

2440 Palm Ridge Road, Sanibel, FL 33957

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$9,950,000

8,300 SF

Entitled Land Parcel For Sale

Approved mixed-use development with apartments and commercial space.

430 SW 47th Terrace, Cape Coral, FL 33914

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Mixed-Use Redevelopment Opportunity, Fort Myers

$3,900,000

0.42 Acres

Mixed-Use Redevelopment Opportunity, Fort Myers

Mixed-use redevelopment opportunity in the heart of Fort Myers Beach.

440 Old San Carlos Boulevard, Fort Myers Beach, FL 33931

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Prime Corner Commercial Development Site

$1,990,000

0.35 Acres

Prime Corner Commercial Development Site

Commercial development site with high visibility and traffic exposure.

1725, 1727, 1729 Cape Coral Parkway E, Cape Coral, FL 33904

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$696,000

0.69 Acres

Fort Myers Investment Opportunity

Four parcels with duplex and vacant lots near Lee Hospital.

2243/2245 Altamont Avenue, Fort Myers, FL 33901

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Waterfront Fort Myers Warehouse Opportunity

$3,495,000

1.06 Acres

Waterfront Fort Myers Warehouse Opportunity

Waterfront industrial warehouse with loading docks near Downtown Fort Myers.

3131 E Riverside Drive, Fort Myers, FL 33916

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Renovated Commercial Property on Fowler Street

$1,249,900

6,200 SF

Renovated Commercial Property on Fowler Street

Fully renovated commercial building with flexible space in Fort Myers.

2730 Fowler Street, Fort Myers, FL 33901

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$460,000

0.23 Acres

Cape Coral Mixed-Use Income Property

Versatile duplex with commercial space and residential unit.

2826 Santa Barbara Boulevard, Cape Coral, FL 33914

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Gulfside Mixed-Use Development Opportunity

$3,349,000

0.40 Acres

Gulfside Mixed-Use Development Opportunity

Unique gulfside property with mixed-use potential near resorts.

2096 ESTERO Boulevard, Fort Myers Beach, FL 33931

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$1,150,000

0.26 Acres

Cape Coral Parkway Commercial Property

High-visibility property in a desirable Cape Coral location.

429 Cape Coral Parkway E, Cape Coral, FL 33904

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$250,000

0.16 Acres

Corner Lot in Downtown Cape

High-exposure commercial property in downtown Cape Coral investment opportunity.

4632 SE 15th Avenue, Cape Coral, FL 33904

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$2,500,000

0.11 Acres

Fort Myers Beach Mixed-Use Opportunity

Prime development site near the Gulf in Fort Myers Beach.

67 Miramar Street, Fort Myers Beach, FL 33931

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High-Visibility Retail and Industrial Facility

$2,400,000

1.00 Acre

High-Visibility Retail and Industrial Facility

Freestanding retail and industrial facility in Fort Myers for sale.

2941 Fowler St, Fort Myers, FL 33901

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Mixed-Use Property with Retail Potential

$499,000

1,746 SF

Mixed-Use Property with Retail Potential

Mixed-use property with retail space, updated features, and historic charm.

1793 Fowler Street, Fort Myers, FL 33901

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$21,950,000

0.33 Acres

Mixed-Use Development Site with Plans

Mixed-use development site with plans in downtown Cape Coral.

1415 Cape Coral Parkway E, Cape Coral, FL 33904

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

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Miami Development Opportunity on NW 27th

33,600 SF vacant land near transit with development potential.

6611 NW 27 Avenue, Miami, FL 33147

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$1,850/Mo

Atlanta Land for Lease

3-acre commercial land available for lease in Atlanta, GA.

1057 Constitution Road SW, Atlanta, GA 30315

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$6,000/Mo

Prime Commercial Acres For Lease

4.12 acres of commercial land for lease in Rainsville, AL.

4.12 Acres Al Highway 35, Rainsville, AL 35986

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Baton Rouge Commercial Parcel For Rent

1.33-acre commercial parcel in a prime Baton Rouge location.

7597 Jefferson Hwy, Baton Rouge, LA 70806

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Lee County, FL Mixed-use properties Leasing Opportunities Market Analysis

Explore Mixed-use properties leasing options in Lee County, FL with 6 listings featured on our commercial real estate exchange. The current inventory includes 41,200 square feet of properties with an estimated lease value of $42 SF/Yr.

Estimated lease rates for Mixed-use properties in Lee County, FL begin at $12 SF/Yr, with an average of $21 SF/Yr and extend to $30 SF/Yr.

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