Mixed-Use

Lee County, FL Mixed-use Properties for Lease

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Mixed-Use Office/Retail Suite
Updated: Jul 3
Mixed-Use Office/Retail Suite

6035 Estero Boulevard, Fort Myers Beach, FL 33931

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1,420 sqft
1,420 RSF mixed‑use office and retail suite
132 feet of frontage along Estero Boulevard
Private entrance and open interior layout
Expanded CB zoning supports office, retail, restaurant, medical, wellness, and yoga uses
Concrete‑block construction with a metal roof
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Retail Space in Lifestyle Center
Updated: Aug 5, 2025
Retail Space in Lifestyle Center

27800 Bonita Grande Dr, Bonita Springs, FL 34135

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1,500 sqft
1,625‑square‑foot retail space available for lease
Mixed‑use center with approximately 200,000± SF of restaurant and retail space
Development includes 400 luxury apartments and a 165‑key hotel
1,300 linear feet of frontage along Bonita Beach Road
First lighted intersection east of I‑75, near Exit 118
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Retail Space in Open-Air Center
Retail Space in Open-Air Center

8012 Mediterranean Drive, Estero, FL 33928

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Positioned within a mixed-use destination alongside Apple, Target, Nordstrom Rack, and Total Wine.

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Mixed-Use Development in Fort Myers
Mixed-Use Development in Fort Myers

1380-1400 Colonial Blvd, Fort Myers, FL 33907

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40,000 sqft

Mixed-use development with retail, office, and medical spaces for lease.

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Retail and Office Center
Retail and Office Center

13451 Mcgregor Blvd, Fort Myers, FL 33919

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1,179 sqft

Prominent retail and office center with ample parking, featuring shops and restaurants, including long-term tenants Prawnbroker and Blue Sushi.

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Alico Commercial Park7916 Drew Cir
Alico Commercial Park7916 Drew Cir

7916 Drew Cir, Fort Myers, FL 33967, Fort Myers, FL 33967

$14.50 SF/Yr

26,611 SF of 4-Star Industrial Space Available in Fort Myers, FL 33967

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Office, Retail, and Warehouse Units
Office, Retail, and Warehouse Units

1939 Park Meadows Dr, Fort Myers, FL 33907

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1,200 sqft

Office, retail, and warehouse units available for lease.

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Based on your search, we've compiled 57 Potential Opportunities for your consideration. Besides 7 Active listings in Lee County, FL, we suggest exploring alternatives. Similar 50 Properties for Sales.

Similar Spaces for Sale in Lee County, FL

Consider Similar Space for Sale. We found 50 Spaces matching your search parameters.

Renovated Commercial Property on Fowler Street
Renovated Commercial Property on Fowler Street

2730 Fowler Street, Fort Myers, FL 33901

$999,000
6,200 sqft 0.46 AC lot

Fully renovated commercial building with flexible space in Fort Myers.

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Mixed-Use Property with Residential Units
Mixed-Use Property with Residential Units

2251 GRAND Avenue, Fort Myers, FL 33901

$1,200,000
4,688 sqft 0.15 AC lot

Two renovated upstairs residences complement flexible ground-floor commercial space.

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Shopping Center with Pylon Signage
Shopping Center with Pylon Signage

12709-12731 McGregor Blvd, Fort Myers, FL 33919

$4,970,000
3.72 AC lot

Neighborhood center with access from College Pkwy and McGregor Blvd, parking, landscaping, and a varied commercial tenant mix.

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Commercial Mixed-Use Assemblage
Commercial Mixed-Use Assemblage

13160, 13170, 13180 & 13192 North Cleveland Avenue, North Fort Myers, FL 33903

$7,000,000
35,935 sqft

Four parcels combine existing retail and commercial improvements under CG, C-1A, and C-2 zoning.

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Commercial Land with Development Plans
Commercial Land with Development Plans

1415 Cape Coral Parkway E, Cape Coral, FL 33904

$2,490,000
0.33 AC lot

Entitled site with plans for apartments, executive offices, and a ground-floor cafe in downtown Cape Coral.

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Mixed-Use Duplex with Commercial Space
Mixed-Use Duplex with Commercial Space

2826 Santa Barbara Boulevard, Cape Coral, FL 33914

$460,000
2,406 sqft

MR zoning supports a live-work arrangement with commercial and residential components.

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Commercial Land with Boulevard Exposure
Commercial Land with Boulevard Exposure

1698 Estero Boulevard, Fort Myers Beach, FL 33931

$1,500,000
0.11 AC lot

Commercial land along Fort Myers Beach’s primary corridor, near Gulf beaches, dining, retail, lodging, and entertainment.

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Mixed-Use Commercial Property
Mixed-Use Commercial Property

16641 San Carlos Boulevard, Fort Myers, FL 33908

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5,965 sqft 1.41 AC lot

Dual commercial zoning supports office, retail, restaurant, and service-oriented uses.

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Mixed-Use Property with Lake Views
Mixed-Use Property with Lake Views

2430 Palm Ridge Road, Sanibel, FL 33957

$2,989,000
0.99 AC lot

Three buildings combine leased commercial suites with remodeled apartments and residential outlooks over the lake.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

19011 San Carlos Boulevard, Fort Myers Beach, FL 33931

$1,075,000
0.20 AC lot

Freestanding commercial property with three upstairs apartments, shared laundry, storage areas, and a ground-level space requiring refurbishment.

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Commercial Sale
Commercial Sale

1165-1161 Estero Blvd, Fort Myers Beach, FL 33931

$3,800,000
5,568 sqft 0.16 AC lot

Mixed-use properties · 5,568 SF

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Cape Coral Mixed-Use Opportunity
Cape Coral Mixed-Use Opportunity

862 Lafayette St, Cape Coral, FL 33904

$2,970,000
17,564 sqft

Two-story, 17,500+ sq ft building in downtown Cape Coral.

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Turn-Key Showroom and Office Building
Turn-Key Showroom and Office Building

3327 Railroad St, Fort Myers, FL 33916

Contact for pricing
8,240 sqft 0.81 AC lot

Showroom and office building with storage near downtown Fort Myers.

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Prime Mixed-Use Development Opportunity
Prime Mixed-Use Development Opportunity

2915 Estero Boulevard, Fort Myers Beach, FL 33931

$1,095,000
0.11 AC lot

Cleared lot on Estero Blvd, steps from the Gulf.

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Profitable Fort Myers Investment Opportunity
Profitable Fort Myers Investment Opportunity

3775 Fowler ST, Fort Myers, FL 33901

$2,025,000
12,778 sqft 0.99 AC lot

Well-maintained, fully leased mixed-use building with long-term tenants.

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Mixed-Use Building with 3 Apartments
Mixed-Use Building with 3 Apartments

1161 Estero Boulevard, Fort Myers Beach, FL 33931

$3,800,000
0.17 AC lot

Two-story property combines residential rentals with street-level commercial space in a pedestrian-oriented beach setting.

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Mixed-Use Property with Two Condos
Mixed-Use Property with Two Condos

2251 Grand Avenue, Fort Myers, FL 33901

$1,999,999
0.15 AC lot

Renovated residential units occupy the upper level above a flexible ground-floor commercial studio.

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Lee County, FL Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in Lee County, FL with 7 listings featured on our commercial real estate exchange. The current inventory includes 45,299 square feet of properties with an estimated lease value of $14.50.

Estimated lease rates for Mixed-use properties in Lee County, FL average $14.50 SF/Yr.
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