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    Sanibel, FL Office Spaces for Lease

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    Fort Myers Beach, FL Fort Myers, FL Saint James City, FL
    Sanibel Office Space Available
    $22 SF/Yr
    3,226 SF
    Sanibel Office Space Available

    4301 Sanibel Captiva Rd, Sanibel, FL

    Office space available for rent in Sanibel, Florida.
    • Office space available for rent
    • Located in Sanibel, Florida
    Updated: Nov 25, 2025
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    Sanibel Office Space For Rent
    $30 SF/Yr
    1,125 SF
    Sanibel Office Space For Rent

    1530 Periwinkle Way, Sanibel, FL

    Second floor office space available on Periwinkle Way.
    • High visibility location on Periwinkle Way
    • Liberal GC commercial zoning in Sanibel, FL
    • Heavy seasonal and local traffic area
    • 1,125 +/- Sqft of space
    • 2nd floor space with elevator
    Updated: Jan 30, 2025
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    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 2 Active listings in Sanibel, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Waterfront Retail-Office Space
    $20 SF/Yr
    1,416 SF
    Waterfront Retail-Office Space

    For lease in the heart of St. James City, this waterfront space combines retail presence with office utility.

    3310 Stringfellow Rd, Saint James City, FL 33956

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    Remodeled Office Spaces Available
    $14 SF/Yr
    Remodeled Office Spaces Available

    Newly remodeled office spaces for lease with tenant build-out.

    Saint James City, FL 33956

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    Move-in Ready Iona Community Office
    Contact for pricing
    2,607 SF
    Move-in Ready Iona Community Office

    2,607± Sq. Ft. office space in a growing corridor.

    16680 McGregor Blvd, Fort Myers, FL 33908

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    Prime Retail/Office/Medical Space Available
    Contact for pricing
    2,000 SF
    Prime Retail/Office/Medical Space Available

    Retail, office, and medical spaces with high visibility frontage.

    16681 McGregor Blvd, Fort Myers, FL

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    Similar Spaces for Sale in Sanibel, FL

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Sanibel Island Commercial Property
    $1,495,000
    2,827 SF
    Sanibel Island Commercial Property

    Highly visible commercial property in Sanibel's Town Center corridor.

    2341 Palm Ridge Road, Sanibel, FL 33957

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    Sanibel Office Suite For Sale
    $329,000
    0.11 Acres
    Sanibel Office Suite For Sale

    Bright, versatile office suite in central Sanibel location.

    2323 Wooster Lane, Sanibel, FL 33957

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    Prime Commercial Lot on Sanibel
    $2,950,000
    1.08 Acres
    Prime Commercial Lot on Sanibel

    High-visibility commercial lot ideal for restaurant, retail, or office.

    1625 Periwinkle Way, Sanibel, FL 33957

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    Prime Commercial Space on Periwinkle
    $795,000
    0.04 Acres
    Prime Commercial Space on Periwinkle

    Commercial building with high visibility on a high-traffic island corridor.

    1025 Periwinkle Way, Sanibel, FL 33957

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    Refreshed Olde Florida-Style Office
    $1,100,000
    0.04 Acres
    Refreshed Olde Florida-Style Office

    Distinctive office campus with flexible spaces on Sanibel's main artery.

    1149 Periwinkle Way, Sanibel, FL 33957

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    Renovated Office Condo on Sanibel
    $225,000
    0.14 Acres
    Renovated Office Condo on Sanibel

    Completely renovated office condo in the heart of Sanibel Island.

    1640 Periwinkle Way, Sanibel, FL 33957

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    Sanibel Island Commercial Property For Sale
    $1,495,000
    2,827 SF
    Sanibel Island Commercial Property For Sale

    Highly visible commercial property in Sanibel Island's Town Center.

    2341 Palm Ridge Rd A, B, C, Sanibel, FL 33957

    View details
    Sanibel Office Suite For Sale
    $349,000
    Sanibel Office Suite For Sale

    Bright, versatile office suite in central Sanibel location.

    2323 Wooster Ln 1, Sanibel, FL 33957

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    Sanibel Commercial Building For Sale
    $1,095,000
    3,000 SF
    Sanibel Commercial Building For Sale

    Commercial building with open floor plan and residential potential.

    905 Fitzhugh Street, Sanibel, FL 33957

    View details
    Completely Renovated Office Condo
    $225,000
    987 SF
    Completely Renovated Office Condo

    Turnkey, fully renovated office condo with built-in workspaces, multiple offices, and in-unit amenities for professional use.

    3-1640 Periwinkle Way, Sanibel, FL 33957

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lot on Franklin Avenue
    Contact for pricing
    10,203 SF
    Commercial Lot on Franklin Avenue

    Commercial lot zoned CG, great location for various businesses.

    16220 Franklin Avenue, Port Charlotte, FL 33953

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    Commercial Land Near Shopping
    $21,000 SF/Yr
    200,000 SF
    Commercial Land Near Shopping

    Commercial land for rent, conveniently located near shopping.

    6012 LORRAINE ROAD, Bradenton, FL 34211

    View details
    Lakeland Commercial Business Park Spaces
    Contact for pricing
    Lakeland Commercial Business Park Spaces

    Commercial spaces for lease in West Lakeland business park.

    2525 Drane Field Road, Lakeland, FL 33811

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    Downtown Winter Haven Commercial Land
    $29,940 SF/Yr
    Downtown Winter Haven Commercial Land

    City-approved commercial land in a growing business district.

    511 AVENUE G NW, Winter Haven, FL 33881

    View details

    Sanibel, FL Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Sanibel, FL with 2 listings featured on our commercial real estate exchange. The current inventory includes 4,351 square feet of properties with an estimated lease value of $52 SF/Yr.

    Estimated lease rates for Office Spaces in Sanibel, FL begin at $22 SF/Yr, with an average of $26 SF/Yr and extend to $30 SF/Yr.
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