Columbia County, FL Office Spaces for Rent & Lease

Updated: Jan 8

Divisible Fitness Center

484 SW COMMERCE DR, B2 #115, Lake City, FL 32025

Contact for pricing

8,400 sqft 10.11 AC lot

8,400 square feet; currently used as a gym
Divisible space offered for medical, retail, or office use
COM zoning
Interstate 75 visibility, with convenient access
Lighted parking

View details

Updated: Jun 25

Medical Office Corner Suite

229 Southwest Main Boulevard, Lake City, FL 32025

$15 SF/Yr

Two lease spaces in a Class B medical office built in 1925
Corner lot with two access points and strong frontage along Main Boulevard
Traffic count of 13,000± vehicles per day along the major corridor
Currently configured as a speech/OT therapy center with flexible medical office use
Surrounded by retail and professional services

View details

Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 2 Active listings in Columbia County, FL, we suggest exploring alternatives. Similar 23 Properties for Sales.

Similar Spaces for Sale in Columbia County, FL

Consider Similar Space for Sale. We found 23 Spaces matching your search parameters.

Multi-Tenant Office Buildings

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Two occupied buildings provide an established office setting with potential for future owner occupancy.

View details

Highway-Frontage Flex Space

2832 SW MAIN BLVD., Lake City, FL 32025

$560,000

3,168 sqft 1.50 AC lot

Open lobby, adjoining offices, and garage space support office, storage, and equipment-oriented use.

View details

Occupied Income-Producing Office Building

885 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

6,054 sqft

Established commercial setting with existing tenants and future owner-user flexibility.

View details

Income-Producing Office Buildings

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Two fully occupied office buildings support ongoing tenancy and future owner-user flexibility.

View details

Office Building with Leased Tenants

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

3,419 sqft

The property is fully occupied, with leases scheduled to renew in 2027 and 2028.

View details

Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

2,635 sqft

Current tenancy includes leases with renewal dates in 2027 and 2028.

View details

Fully Occupied Office Building

885 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

6,054 sqft

Established professional-office setting with tenants in place and lease renewals scheduled through 2028.

View details

Historic Mixed-Use Property

398 S MARION Avenue, Lake City, FL 32025

$355,000

2,559 sqft 0.32 AC lot

Two-story commercial property with a separate carriage house, apartment, covered porch, and updated building systems.

View details

Historic Two-Story Office Building

433 S MARION AVENUE, Lake City, FL 32025

$349,900

3,968 sqft 0.65 AC lot

Flexible two-story layout with multiple rooms, common areas, and public and private restrooms.

View details

Restored Two-Story Office Building

398 S MARION, Lake City, FL 32025

$355,000

2,079 sqft 0.32 AC lot

Historic downtown property with a separate carriage house, apartment, and updated building systems.

View details

Office Building with Central Air

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Commercial office property with central air conditioning and a 1993 construction date.

View details

Fully Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

2,500 sqft

Established commercial-corridor office asset with long-term occupants and lease renewals scheduled in 2027 and 2028.

View details

New Construction Warehouse with Office

372 Southwest Windswept Glen, Lake City, FL 32024

$1,850,000

7,500 sqft 2.01 AC lot

New 7,500 SF warehouse with office space for sale.

View details

Historic Two-Story Office Building

398 S Marion Ave, Lake City, FL 32025

$355,000

2,559 sqft

Restored commercial property with updated systems, architectural character, and a separate carriage house with apartment space.

View details

Historic Two-Story Office Building

398 S MARION, Lake City, FL 32025

$355,000

2,079 sqft

Commercial General zoning, updated systems, and a separate carriage house support varied business configurations.

View details

Fenced Flex Space with Warehouse

3887 E US HIGHWAY 90, Lake City, FL 32055

$699,000

15,000 sqft 1.72 AC lot

Fenced and gated commercial property combining warehouse, office, and apartment components.

View details

Multi-Unit Office Building

725 Se Baya Dr, Lake City, FL 32025

$615,000

5,571 sqft

Seven office units are split across two floors, with a recently installed roof and strong road exposure.

View details

Professional Office Building

701 SW State Road 47, Lake City, FL 32025

Contact for pricing

4,139 sqft

The property is zoned CI and offers ample parking for office users.

View details

Mixed-Use Property with US-41 Frontage

1226 SW MAIN BLVD, Lake City, FL 32025

Contact for pricing

4,512 sqft

Commercially zoned property with city utilities and access along a major Lake City corridor.

View details

Warehouse with Fenced Yard and Office

196 NE CHESTNUT AVE, Lake City, FL 32055

Contact for pricing

7,844 sqft

Warehouse with multiple roll-up doors and updated climatized office plus fenced industrial yard for secure equipment storage.

View details

Fully Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

Established commercial corridor setting with lease renewals scheduled in 2027 and 2028.

View details

Commercial Building with Residential Income

1664 Southeast Baya Drive, Lake City, FL 32025

Contact for pricing

1,152 sqft

Commercial building with additional income from residential property.

View details

Columbia County, FL Office Spaces for Lease

484 SW COMMERCE DR, B2 #115, Lake City, FL 32025

229 Southwest Main Boulevard, Lake City, FL 32025