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Lee County, FL Office Spaces for Lease

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Fort Myers Office/Retail Space
Fort Myers Office/Retail Space

4531 Deleon Street, Fort Myers, FL 33907

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Professional office/retail space in high visibility Fort Myers location.

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Based on your search, we've compiled 493 Potential Opportunities for your consideration. Besides 217 Active listings in Lee County, FL, we suggest exploring alternatives. Consider Similar 276 Spaces for Sales.

Similar Spaces for Sale in Lee County, FL

Consider Similar Space for Sale. We found 276 Spaces matching your search parameters.

Retail/Flex/Office Building on Del Prado
Retail/Flex/Office Building on Del Prado

4529 Del Prado Boulevard S, Cape Coral, FL 33904

$1,150,000
3,840 sqft 0.15 AC lot

3,840 SF retail/flex/office building in high-visibility location.

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Office/Medical Suite with Spa Tenant
Office/Medical Suite with Spa Tenant

12545 New Brittany Boulevard, Fort Myers, FL 33907

$759,900
3,264 sqft 0.08 AC lot

Two updated office/medical units offer an income-leaning setup with a spa lease through 2028 and an available companion suite.

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Sanibel Island Commercial Property
Sanibel Island Commercial Property

2341 Palm Ridge Road, Sanibel, FL 33957

$1,495,000
2,827 sqft 0.08 AC lot

Highly visible commercial property in Sanibel's Town Center corridor.

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San Carlos Blvd Office Building
San Carlos Blvd Office Building

16048 SAN CARLOS BOULEVARD, Fort Myers, FL 33908

$1,100,000
3,960 sqft 0.69 AC lot

Class B office building on high-traffic San Carlos Blvd.

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C1 Flex Office and Industrial Site
C1 Flex Office and Industrial Site

3671 Fowler St, Fort Myers, FL 33901

$2,800,000
5,800 sqft 1.30 AC lot

Multiple building options on one C1-zoned site support businesses needing office space alongside flexible expansion.

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Multi-Unit Professional Office Building
Multi-Unit Professional Office Building

1314-1322 Lafayette Street, Cape Coral, FL 33904

$1,295,000
0.42 AC lot

Fully leased office building configured as five units, designed for professional tenants with potential to expand.

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Two-Unit Mixed-Use Building
Two-Unit Mixed-Use Building

1615 SE 47th Terrace, Cape Coral, FL 33904

$1,072,000
0.22 AC lot

Good-condition two-unit property in the CRA district, zoned SC, currently with a bakery unit through August 2026.

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Professional Office with Canal Access
Professional Office with Canal Access

1218 Del Prado Boulevard S, Cape Coral, FL 33990

$749,000
0.24 AC lot

Three-office layout with a shared lobby, located at a signalized intersection with canal frontage for client-friendly access.

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C-1 Zoned Commercial Property
C-1 Zoned Commercial Property

2959 Oleander Street, St James City, FL 33956

$750,000
0.22 AC lot

Small commercial site on Stringfellow Road, suited for retail, office, or marine-related neighborhood-serving uses.

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Class A Flex Building with 14-Foot Door
Class A Flex Building with 14-Foot Door

3820 Via Del Rey, Bonita Springs, FL 34134

$4,500,000
0.78 AC lot

Modern flex facility with high-end office buildout, reception, and a large garage/receiving bay.

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Church-Configured Flex Facility
Church-Configured Flex Facility

300 Leonard Boulevard N, Lehigh Acres, FL 33971

$1,000,000
3,850 sqft 0.65 AC lot

Flex industrial space combining two units, with an open main area, small office, and private restroom.

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Remodeled Office Condo Suite
Remodeled Office Condo Suite

2401 First Street, Fort Myers, FL 33901

$995,000
5,874 sqft 0.29 AC lot

Third-floor office condo with 24-hour controlled access and potential rooftop terrace, with water included in CAM.

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End-Unit Office Condominium
End-Unit Office Condominium

25110 Bernwood Dr, Bonita Springs, FL 34135

$659,900
0.27 AC lot

Office condo with reception, kitchen, and full bath, plus front and rear parking in a business park setting.

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Cape Coral Commercial Land Available
Cape Coral Commercial Land Available

617 SW 4th Street, Cape Coral, FL 33991

$190,000
15,000 sqft 0.34 AC lot

Commercial land in growing Pine Island Road District, Cape Coral.

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Church Building with Conversion Potential
Church Building with Conversion Potential

3657 Central Avenue, Fort Myers, FL 33901

$1,100,000
0.76 AC lot

Well-maintained church building with kitchenette, multiple rooms, and flexible interior space for office, medical, education, or faith use.

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Mixed-Use Property with Fenced Parking
Mixed-Use Property with Fenced Parking

2251 GRAND AVENUE, Fort Myers, FL 33901

$1,200,000
4,688 sqft 0.15 AC lot

Three distinct income spaces upstairs residential and ground-floor studio, supported by dedicated fenced parking for tenants and visitors.

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Live-Work Property with Covered Space
Live-Work Property with Covered Space

2850 Packinghouse Road, Alva, FL 33920

$390,000
1.88 AC lot

Zoned AG-2 live-work site with multiple offices, remodeled restroom, and covered space for equipment or vehicles.

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Concrete Block Medical Office Portfolio
Concrete Block Medical Office Portfolio

3900 Broadway, Fort Myers, FL 33901

$3,400,000
2.72 AC lot

Four concrete block office buildings on 2.72 acres with strong occupancy, frontage on Broadway, and ample parking.

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Medical Office Building with Parking
Medical Office Building with Parking

331 Cape Coral Parkway W, Cape Coral, FL 33914

$1,350,000
0.47 AC lot

For sale office building with ample parking and original metal roof on a corner lot.

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Waterfront Fort Myers Warehouse Opportunity
Waterfront Fort Myers Warehouse Opportunity

3131 E Riverside Drive, Fort Myers, FL 33916

$3,495,000
7,500 sqft 1.06 AC lot

Waterfront industrial warehouse with loading docks near Downtown Fort Myers.

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Medical Office Space For Sale
Medical Office Space For Sale

22904 Lyden Drive, Estero, FL 33928

$1,750,000
3,651 sqft 0.04 AC lot

Newly constructed medical office space in a desirable Estero location.

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Two-Story Freestanding Medical Office
Two-Story Freestanding Medical Office

12731 New Brittany Blvd, Fort Myers, FL 33907

$4,900,000
1.69 AC lot

Two-story concrete block medical building with surgical buildout and flexible occupancy options for owner-users or investors.

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Commercial Land Parcel with Existing Property
Commercial Land Parcel with Existing Property

1010 NE 9th Street, Cape Coral, FL 33909

$995,000
0.23 AC lot

Two parcels sold together near NE 9th Street, offering space for expansion, parking, storage, or redevelopment subject to approvals.

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