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    Rochester, NY
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    Rochester, NY Office Buildings for Lease

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    Henrietta, NY Penfield, NY Webster, NY
    20 results
    Versatile Office Building in Rochester
    $590,000 SF/Yr
    8,320 SF

    Versatile Office Building in Rochester

    1171 Titus Avenue, Rochester, NY 14617

    8320 sq ft office building with flexible leasing options.

    • Strategic location at the corner of Titus Ave and Portland Ave in the heart of Irondequoit.
    • Large on‑site parking lot with over 50 spaces.
    • Versatile floor plan allowing for spaces from 350 sq ft to 4000 sq ft.
    • New tear‑off roof installed in January 2025.
    • High‑traffic area with great exposure, minutes from Route 104 and 590 expressway.
    Updated: Nov 1, 2025
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    Medical & Professional Office Space
    Contact for pricing
    50,816 SF

    Medical & Professional Office Space

    200 & 300 White Spruce Boulevard, Rochester, NY 14623

    Multi-tenant medical and professional office space for lease.

    • Extensively renovated in 2020 with new siding, roofs, lighting, entry canopy, common areas, and parking lots.
    • Located near the University of Rochester Medical Center (URMC).
    • Offers 50,816 rentable square feet of multi‑tenant medical and professional office space.
    • Currently 76.7% occupied, providing income with upside potential.
    • Superior expressway access.
    Updated: Mar 25
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    Versatile Office Building Near Airport
    $575,000 SF/Yr
    9,690 SF

    Versatile Office Building Near Airport

    Well-maintained office building near Rochester Airport with flexible workspace.

    300 Buell Rd, Gates, NY 14624
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    Prime Office Building Near Eastman
    $449,900 SF/Yr

    Prime Office Building Near Eastman

    Office building in prime location near Eastman Theatre and restaurants.

    57 University Ave, Rochester, NY 14605
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    Stately Office Building in Rochester
    $925/Mo
    21,342 SF

    Stately Office Building in Rochester

    Charming office building with modern amenities and convenient location.

    16 N Goodman Street, Rochester, NY 14607
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    Modern Office Space Near Airport
    Contact for pricing
    2,500 SF

    Modern Office Space Near Airport

    Modern office building with ample natural light and convenient location.

    90 Air Park Drive, Rochester, NY 14624
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    Prominent Office Building Near Downtown
    $10 SF/Yr
    150,000 SF

    Prominent Office Building Near Downtown

    Six-story office building near Eastman Kodak HQ and MCC.

    150 Verona St, Rochester, NY
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    Remodeled Office Building For Rent
    Contact for pricing
    1,250 SF

    Remodeled Office Building For Rent

    Handicap accessible, move-in ready office space near shopping centers.

    2510 Chili Ave, Rochester, NY
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    Rochester Office Building For Rent
    Contact for pricing
    52,600 SF

    Rochester Office Building For Rent

    52,600 SF office building with ample parking near airport.

    280 Kenneth Dr, Rochester, NY
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    Stand-Alone Building Available for Rent
    Contact for pricing
    28,500 SF

    Stand-Alone Building Available for Rent

    Stand-alone building with lab and office spaces, immediate occupancy.

    1777 E Henrietta Rd, Rochester, NY
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    Professional/Medical Office Building For Rent
    Contact for pricing
    31,500 SF

    Professional/Medical Office Building For Rent

    31,500 SF professional/medical office building with suites available.

    120 Erie Canal Dr, Rochester, NY
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    Class A Office Building
    $15 SF/Yr
    170,000 SF

    Class A Office Building

    Class A office building with private parking garage in Rochester.

    255 E Ave, Rochester, NY
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    Modern Office Building Near Airport
    Contact for pricing
    42,000 SF

    Modern Office Building Near Airport

    Four-story office building with suites available for immediate occupancy.

    90 Air Park Dr, Rochester, NY 14624
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    Upscale Office/Showroom Space Available
    Contact for pricing
    10,536 SF

    Upscale Office/Showroom Space Available

    Two-story office building ideal for industrial space or showroom.

    3445 Winton Pl, Rochester, NY
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    Downtown Rochester Office and Retail
    $20 SF/Yr

    Downtown Rochester Office and Retail

    Modern office tower with retail space in downtown Rochester.

    One South Clinton Ave, Rochester, NY 14604
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    Available Commercial Space For Lease
    Contact for pricing
    780,915 SF

    Available Commercial Space For Lease

    780,915 SF available in Rochester, NY.

    1405 St Paul St, Rochester, NY 14621
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    Brighton-Henrietta Corridor Office Space
    $15 SF/Yr
    100,000 SF

    Brighton-Henrietta Corridor Office Space

    Up to 100,000 SF available in Brighton-Henrietta corridor.

    500 Canal View Blvd, Rochester, NY 14623
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    Rochester Office Building for Lease
    Contact for pricing
    5,800 SF

    Rochester Office Building for Lease

    Two-story office building in Rochester's vibrant East End district.

    441 East Ave, Rochester, NY
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    Rochester Office Space For Lease
    Contact for pricing

    Rochester Office Space For Lease

    15-story office building in Rochester's Innovation Zone.

    2 State St, Rochester, NY 14614
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    Harro East Athletic Club Space
    Contact for pricing

    Harro East Athletic Club Space

    Downtown Rochester athletic club with gym, field house, and more.

    400 Andrews St, Rochester, NY 14604
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    Based on your search, we've compiled 42 Potential Opportunities for your consideration. Besides 20 Active listings in Rochester, NY, we suggest exploring alternatives. Similar 22 Properties for Sales.

    Similar Spaces for Sale in Rochester, NY

    Consider Similar Space for Sale. We found 22 Spaces matching your search parameters.

    Free-Standing Building in Henrietta
    $899,900
    11,624 SF
    Free-Standing Building in Henrietta

    Commercial building with flexible layout and great parking in Rochester.

    1567 E Henrietta Road, Rochester, NY 14623

    View details
    Historic Rochester Building Redevelopment Opportunity
    $265,000
    16,586 SF
    Historic Rochester Building Redevelopment Opportunity

    16,586 SF building in downtown Rochester, prime for redevelopment.

    159 Alexander Street, Rochester, NY 14607

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    Freestanding Business Building For Sale
    $299,000
    1,657 SF
    Freestanding Business Building For Sale

    Turnkey, highly visible building with ample parking and renovated features.

    4105 W Henrietta Road, Rochester, NY 14623

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    Two-Story Medical/Office Building For Sale
    $575,000
    4,000 SF
    Two-Story Medical/Office Building For Sale

    Vacant two-story building suitable for medical, office, or childcare uses.

    353 Island Cottage Rd, Rochester, NY 14612

    View details

    Rochester, NY Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Rochester, NY with 20 listings featured on our commercial real estate exchange. The current inventory includes 459,352 square feet of properties with an estimated lease value of $1,165,042.

    Estimated lease rates for Office buildings in Rochester, NY begin at $0.52 SF/Yr, with an average of $194,173 and extend to $590,000.
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    Most Searched ZIP Codes in Rochester, NY

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    • 14604
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