Mixed-Use

Monroe County, FL Mixed-use Properties for Sale

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36 properties
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Mixed-Use Property with Work Areas
Updated: Aug 28
Mixed-Use Property with Work Areas

5670 Laurel Avenue, Stock Island, FL 33040

$1,749,000
5,258 sqft 0.29 AC lot
Two 50' x 125' lots totaling 0.29 acres
5,258‑square‑foot ground‑level CBS building constructed in 1980
100 feet of frontage and 125 feet of depth on Laurel Avenue
Covered and outdoor work areas with off‑street parking
MU - Mixed Use District zoning
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Six-Suite Mixed-Use Building
Updated: Apr 13
Six-Suite Mixed-Use Building

92295 Old State Road, Key Largo, FL 33070

$2,850,000
6,241 sqft 0.86 AC lot
Six separate commercial suites connected by exterior walkways
313 feet of US‑1 highway frontage
0.86‑acre fenced lot
Each suite includes a half bathroom; two additional restrooms serve the property
Northbound US‑1 location with cross‑street access to the southbound lane
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Mixed-Use Property with Six Storefronts
Mixed-Use Property with Six Storefronts

218 Whitehead Street, Key West, FL 33040

$4,200,000
7,755 sqft 0.16 AC lot

Corner property combines six retail spaces with a three-bedroom, two-bath apartment and separate utility meters.

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High-Frontage Mixed-Use Building with Suites
High-Frontage Mixed-Use Building with Suites

92295 Old State Road, #4A, Key Largo, FL 33070

$2,850,000
6,214 sqft 0.86 AC lot

Concrete mixed-use building with six exterior-access suites and extensive US-1 frontage for flexible retail, office, and medical use.

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Three-Unit Mixed-Use Property
Three-Unit Mixed-Use Property

1200-1206 White Street, Key West, FL 33040

$1,475,000
3,380 sqft

Commercial condominium offering with established occupants, one vacant unit, and flexible office, retail, service, and restaurant use potential.

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Mixed-Use Commercial Land
Mixed-Use Commercial Land

5331 5th Avenue, Stock Island, FL 33040

$2,050,000
5,705 sqft 0.69 AC lot

The site carries MU zoning and includes seven electric meters and seven water meters.

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Concrete Mixed-Use Building
Concrete Mixed-Use Building

100636 Overseas Highway, Key Largo, FL 33037

$1,790,000
4,910 sqft 0.18 AC lot

Ground-floor commercial space is paired with a renovated three-bedroom, three-bath apartment and rooftop, patio, and yard areas.

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Auto Shop with Covered Work Areas
Auto Shop with Covered Work Areas

5670 Laurel Avenue, Stock Island, FL 33040

$1,749,000
5,258 sqft 0.29 AC lot

Mixed-use zoning supports commercial and residential uses, with licenses covering repair, towing, detailing, rentals, and retail sales.

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Mixed-Use White-Box Space
Mixed-Use White-Box Space

3201 Flagler Avenue, Key West, FL 33040

$749,000
1,491 sqft 0.71 AC lot

White-box commercial space allows buyers to configure the interior for professional, medical office, or retail operations.

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Mixed-Use Property with Storefront
Mixed-Use Property with Storefront

1011 Whitehead Street, Key West, FL 33040

$3,795,000
2,024 sqft 0.03 AC lot

Three furnished one-bedroom residences feature individual kitchens and transient rental licenses.

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Fenced Mixed-Use Commercial Building
Fenced Mixed-Use Commercial Building

4a-92295 Old State Rd, Key Largo, FL 33037

$2,850,000
6,214 sqft 0.86 AC lot

Concrete commercial property with multiple suites, highway frontage, and access serving both directions of US-1.

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Fenced Mixed-Use Property
Fenced Mixed-Use Property

104980 Overseas Highway, Key Largo, FL 33037

$1,200,000
1,024 sqft 0.37 AC lot

MU-zoned property with a concrete building, central air, dual access, and secure perimeter fencing.

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Waterfront Mixed-Use Property
Waterfront Mixed-Use Property

Islamorada, FL 33036

$3,150,000
6,071 sqft 0.35 AC lot

Oceanfront commercial property with marine access, wraparound windows, and space for residential and business uses.

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White Box Commercial Suite
White Box Commercial Suite

3201 Flagler Avenue, #STE 507, Key West, FL 33040

$749,000
1,491 sqft

Under-construction suite with white-box delivery, ADA access, ample parking, and flexibility to split into two units.

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Mixed-Use Building with Drive-Through
Mixed-Use Building with Drive-Through

11401 Overseas Highway, Marathon, FL 33050

$1,533,333
3,429 sqft 0.34 AC lot

MU - Mixed Use Commercial zoning supports office and retail use potential.

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Commercial Land with Mixed-Use Zoning
Commercial Land with Mixed-Use Zoning

5331 5th Avenue, Stock Island, FL 33040

$2,050,000
0.69 AC lot

Four parcels offer utility connections and a mixed-use development framework on Stock Island.

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Mixed-Use Compound with Rental Units
Mixed-Use Compound with Rental Units

82891 Overseas Highway, Islamorada, FL 33036

$2,100,000
476 sqft 0.17 AC lot

Commercial improvements combine a fortified shop-office with multi-unit accommodations and dedicated vehicle staging.

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Mixed-Use Property with Classrooms
Mixed-Use Property with Classrooms

101900 Overseas Hwy, Key Largo, FL 33037

$10,800,000
2.08 AC lot

Gift shop and administrative space support on-site guest services and educational programming.

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Overseas Highway Mixed-Use Investment
Overseas Highway Mixed-Use Investment

7070 Overseas Highway, Marathon, FL 33050

$1,400,000
4,168 sqft

Mixed-use property with commercial space and residential rental units.

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Mixed-Use Property With Restaurant
Mixed-Use Property With Restaurant

405 Petronia Street, Key West, FL 33040

$2,999,999
1,596 sqft 0.05 AC lot

Fully leased property combining residential, office, and detached restaurant components in Key West’s Old Town area.

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Mixed-Use Corner Property
Mixed-Use Corner Property

218 Whitehead Street, Key West, FL 33040

$4,200,000
7,755 sqft

Six retail suites and a three-bedroom apartment combine commercial and residential occupancy in one property.

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Mixed-Use Property with Detached Restaurant
Mixed-Use Property with Detached Restaurant

405 Petronia Street, Key West, FL 33040

$2,999,999
1,596 sqft 0.05 AC lot

Fully rented property combines residential, office, and detached restaurant space.

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Islamorada Mixed-Use Investment Opportunity
Islamorada Mixed-Use Investment Opportunity

88101 Old Highway, Plantation Key, FL 33036

$999,999
2,244 sqft

Two-story mixed-use building with income potential in Islamorada.

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Remodeled 150-Seat Restaurant
Remodeled 150-Seat Restaurant

532 Margaret Street, Key West, FL 33040

$2,500,000
2,490 sqft 0.11 AC lot

Licensed dining property includes indoor-outdoor seating, a full-service bar, commercial kitchen, and an upstairs one-bedroom apartment.

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Monroe County, FL Mixed-Use Properties Market Trends and Statistics

Explore 72 mixed-use properties for sale in Monroe County, FL, showcased through 36 active listings on our real estate platform. These investment opportunities span a total of 107,641 square feet of properties for sale, with an estimated market value of $106,937,330.

Sale prices for multi use buildings in Monroe County, FL start at $99,000, averaging $3,449,591, and reaching up to $10,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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