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    South Carolina Retail Properties & Spaces for Lease

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    1,256 results
    Adaptable Commercial Space in Anderson
    $7,500/Mo

    Adaptable Commercial Space in Anderson

    200 W Benson Street, Anderson, SC 29624

    Prime commercial property in Anderson's historic district for diverse ventures.

    • Prime commercial property in Anderson's historic district.
    • Substantial 12,545 sq ft of adaptable space.
    • Generous 0.4‑acre lot with potential for expansion.
    • Prominent address on Benson Street ensures excellent visibility and accessibility.
    • Architectural character harmonizes with the district's charm.
    Updated: Apr 14
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    Highway 170 Flex/Retail Building
    $7,500/Mo

    Highway 170 Flex/Retail Building

    46 Robert Smalls Parkway, Beaufort, SC 29906

    4,350 SF flex/retail building with high visibility.

    • Excellent visibility and direct frontage on the Spanish Moss Trail.
    • Signalized corner location across from Publix and Beaufort Plaza.
    • Located on rapidly growing Hwy 170 corridor.
    • Versatile layout can be subdivided into multiple units.
    • Significant improvements underway, including interior and exterior paint, new flooring, and cleanup/demo.
    Updated: Mar 17
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    Versatile Flex Space in Myrtle Beach
    $4,750/Mo
    4,110 SF

    Versatile Flex Space in Myrtle Beach

    Adaptable commercial space for lease in the Arts & Innovation District.

    716 8th Ave. N, Myrtle Beach, SC 29577
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    Commercial Space in Beaufort Plaza
    $1,400/Mo

    Commercial Space in Beaufort Plaza

    Retail space available for lease in Beaufort, South Carolina.

    1180 Ribaut Road unit: 7, Beaufort, SC 29902
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    Retail Center Renovation in Little River
    $1,913/Mo
    1,148 SF

    Retail Center Renovation in Little River

    Retail and office spaces available in renovated Little River center.

    4390 Spa Dr., Little River, SC 29566
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    Commercial Space in Downtown Aiken
    $2,000/Mo
    1,204 SF

    Commercial Space in Downtown Aiken

    Commercial lease in downtown Aiken with high visibility and accessibility.

    333 Newberry Street NW, Aiken, SC 29801
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    New Flex Development in Murrells
    $3,000/Mo
    1,625 SF

    New Flex Development in Murrells

    New construction flex space with build-to-suit options available.

    4960 Highway 17, Murrells Inlet, SC 29576
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    Downtown Wagener Commercial Space Available
    $1,695/Mo
    1,375 SF

    Downtown Wagener Commercial Space Available

    Premier commercial space in downtown Wagener, move-in ready and versatile.

    108 Park Street NW, Wagener, SC 29164
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    Historic Pendleton Bank Retail Space
    $3,500/Mo

    Historic Pendleton Bank Retail Space

    Renovated retail space in historic Pendleton Town Square.

    104 Exchange Street, Pendleton, SC 29670
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    Retail/Flex Building on Highway 170
    $11 SF/Yr

    Retail/Flex Building on Highway 170

    19,250 SF retail/flex building with excellent exposure.

    164 Robert Smalls Parkway, Beaufort, SC 29906
    View details
    Retail Space in Little River
    $3,333/Mo
    2,000 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River shopping center.

    4390 Spa Dr., Little River, SC 29566
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    Retail Space in Little River
    $1,931/Mo
    1,159 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River location.

    4390 Spa Dr., Little River, SC 29566
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    Commercial Space in Beaufort, SC
    $3,650/Mo

    Commercial Space in Beaufort, SC

    Highly visible 1,802 SF space for retail or office.

    2631 Boundary Street, Beaufort, SC 29906
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    Downtown Beaufort Commercial Space Available
    $3,300/Mo

    Downtown Beaufort Commercial Space Available

    Versatile commercial space in the heart of Downtown Beaufort.

    700 Bay, Beaufort, SC 29902
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    Murrells Inlet Office Space
    $2,187/Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

    637 Bellamy Ave., Murrells Inlet, SC 29576
    View details
    Aiken Industrial Space For Rent
    $8,000/Mo
    15,080 SF

    Aiken Industrial Space For Rent

    15,080 SF industrial space on Equestrian Corridor.

    2969 Wagener Road unit: A1, Aiken, SC 29801
    View details
    Versatile Commercial Space For Rent
    $4,500/Mo

    Versatile Commercial Space For Rent

    Two-story commercial building with flexible space and high visibility.

    8 Celadon Drive unit: A&B, Beaufort, SC 29907
    View details
    Pawleys Island Class A Office
    $2,250/Mo
    1,800 SF

    Pawleys Island Class A Office

    Class A office space in the heart of Pawleys Island.

    12019 Ocean Hwy., Pawleys Island, SC 29585
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    Versatile Commercial Space in Florence
    $5,000/Mo
    11,390 SF

    Versatile Commercial Space in Florence

    Commercial property with bay doors, ideal for automotive or warehouse.

    374 Darlington St., Florence, SC 29501
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    High-Visibility Gas Station & Store
    $23 SF/Yr

    High-Visibility Gas Station & Store

    Gas station and convenience store with high visibility and traffic.

    5 Lane Street, Yemassee, SC 29945
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    Prime Commercial Site in Port Royal
    $6,000/Mo

    Prime Commercial Site in Port Royal

    High-visibility commercial site ideal for retail, professional, and food businesses.

    1670 Ribaut Road, Port Royal, SC 29935
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    New Retail and Office Spaces
    $6,082/Mo
    2,500 SF

    New Retail and Office Spaces

    New retail and office spaces available in Pawleys Island, SC.

    9601 Ocean Highway, Pawleys Island, SC 29585
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    Restaurant Space Near I-95
    $7,680/Mo
    4,190 SF

    Restaurant Space Near I-95

    Restaurant space for lease with high visibility and traffic.

    3751 W Palmetto St, Florence, SC 29501
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    Prime Retail/Office Space Available
    $3,329/Mo
    1,598 SF

    Prime Retail/Office Space Available

    Highly desirable Pawleys Island mixed-use location. Adaptable space.

    71 Da Gullah Way, Pawleys Island, SC 29585
    View details

    South Carolina Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in South Carolina with 1256 listings featured on our commercial real estate exchange. The current inventory includes 3,802,086 square feet of properties with an estimated lease value of $9,083,120.

    Estimated lease rates for Retail properties & Spaces in South Carolina begin at $0.88 SF/Yr, with an average of $20,596 and extend to $8,700,000.
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