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    Sanibel, FL Commercial Real Estate for Sale

    86 results
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    Renovated Office Condo on Sanibel
    $299,000
    0.14 Acres

    Renovated Office Condo on Sanibel

    1640 Periwinkle Way, Sanibel, FL 33957

    Completely renovated office condo in the heart of Sanibel Island.

    • Prime location on Periwinkle Way in the heart of Sanibel Island.
    • Completely renovated in 2024 with luxury vinyl plank flooring, pristine white cabinetry, and built‑in workspaces.
    • Flexible 987 sq ft office condo suitable for various business types.
    • Includes multiple offices, waiting area, receptionist/assistant space, and restroom within the unit.
    • Equipped with two sinks, washer, dryer, and full‑sized refrigerator.
    Updated: Dec 30, 2025
    View details
    Sanibel Commercial Building For Sale
    $1,200,000
    0.26 Acres

    Sanibel Commercial Building For Sale

    905 Fitzhugh St, Sanibel, FL 33957

    Commercial building with side street frontage in Sanibel, Florida.

    • Prime location off Periwinkle Way.
    • 3,000 sq ft commercial building.
    • 100 ft of side street frontage.
    • Two‑story layout with 1,500 sq ft per floor.
    • Upper floor apartment with 2 bedrooms/offices.
    Updated: Dec 16, 2025
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    Prime Commercial Property on Periwinkle
    $5,500,000
    3.00 Acres

    Prime Commercial Property on Periwinkle

    Commercial property with excellent exposure and road frontage on 3 acres.

    1551 Periwinkle Way, Sanibel, FL 33957
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    Sanibel Island Income-Producing Commercial Property
    $5,400,000
    0.84 Acres

    Sanibel Island Income-Producing Commercial Property

    Income-producing commercial property on Sanibel Island with high visibility.

    1039 Periwinkle Way, Sanibel, FL 33957
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    Prime Sanibel Commercial Landmark
    $3,295,000
    0.49 Acres

    Prime Sanibel Commercial Landmark

    Versatile property on Periwinkle Way with business, investment, and lifestyle potential.

    1446 Periwinkle Way, Sanibel, FL 33957
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    Sanibel Island Office Condo
    $415,000
    0.03 Acres

    Sanibel Island Office Condo

    Turnkey, stabilized office condo on Periwinkle Way, Sanibel Island.

    1101 Periwinkle Way, Sanibel, FL 33957
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    Refreshed Olde Florida-Style Office
    $1,100,000
    0.04 Acres

    Refreshed Olde Florida-Style Office

    Distinctive office campus with flexible spaces on Sanibel's main artery.

    1149 Periwinkle Way, Sanibel, FL 33957
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    Sanibel Island Commercial Property
    $1,200,000
    0.49 Acres

    Sanibel Island Commercial Property

    Commercial property on Sanibel Island with frontage on Periwinkle Way.

    1544 Periwinkle Way, Sanibel, FL 33957
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    Prime Commercial Space on Periwinkle
    $795,000
    0.04 Acres

    Prime Commercial Space on Periwinkle

    Commercial building with high visibility on a high-traffic island corridor.

    1025 Periwinkle Way, Sanibel, FL 33957
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    Established Sanibel Restaurant and Retail
    $1,200,000

    Established Sanibel Restaurant and Retail

    Iconic Sanibel restaurant and retail business for sale.

    1551 Periwinkle Way, Sanibel, FL 33957
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    Historic Sanibel Building For Sale
    $1,250,000
    0.43 Acres

    Historic Sanibel Building For Sale

    Iconic Sanibel building reimagined for modern use in prime location.

    520 Tarpon Bay Rd, Sanibel, FL 33957
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    Sanibel Island Investment Portfolio
    $5,950,000
    0.94 Acres

    Sanibel Island Investment Portfolio

    Four Prime Properties, Gulf Access

    4819 Tradewinds Dr, Sanibel, FL 33957
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    Sanibel Office Condo - Prime Location
    $1,350,250
    3,014 SF

    Sanibel Office Condo - Prime Location

    Vacant Office, 3,014 sq ft, High Visibility

    1149 Periwinkle Way, Sanibel, FL 33957
    View details

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Waterfront Lot with Private Dock
    $325,000
    0.16 Acres

    Waterfront Lot with Private Dock

    Waterfront lot with dock, boat lift, and utilities in place.

    2480 Sycamore St, St James City, FL 33956
    View details
    Waterfront Property Ready for Remodel
    $419,000
    0.23 Acres

    Waterfront Property Ready for Remodel

    Remodel-ready waterfront property with approved permits and boat lifts.

    2560 Baybreeze St, St James City, FL 33956
    View details
    Waterfront Double Lot Paradise
    $475,000
    0.23 Acres

    Waterfront Double Lot Paradise

    Two contiguous buildable lots with direct Gulf access.

    3977 Coconut Dr, Saint James City, FL 33956
    View details
    Waterfront Lot with Gulf Access
    $375,000
    0.09 Acres

    Waterfront Lot with Gulf Access

    Waterfront lot with boat lifts and plunge pool.

    3783 Cherry Ln, Saint James City, FL 33956
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Sanibel Island Mixed-Use Development Opportunity
    $4,750,000
    3.82 Acres

    Sanibel Island Mixed-Use Development Opportunity

    Approved development for restaurant and eight residential dwellings in Sanibel.

    2163 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Development Opportunity on Periwinkle
    $2,999,000
    2.29 Acres

    Sanibel Development Opportunity on Periwinkle

    Iconic Sanibel property with frontage on Periwinkle Way.

    1223 Periwinkle Way, Sanibel, FL 33957
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    Sanibel Commercial/Residential Opportunity
    $1,795,000
    0.50 Acres

    Sanibel Commercial/Residential Opportunity

    Rare 0.498 acre commercial/residential parcel on West Gulf Drive.

    2761 W Gulf Dr, Sanibel, FL 33957
    View details

    Explore Off-Market Properties in Sanibel, FL

    Consider similar Off-Market properties in Sanibel, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    4150 Dingman Dr

    4150 Dingman Dr

    Multifamily properties
    Value Estimation by Request
    4150 Dingman Dr, Sanibel, FL 33957
    View details
    610 Donax St

    610 Donax St

    Residential income properties
    Value Estimation by Request
    610 Donax St, Sanibel, FL 33957
    View details
    Wildlife Preserve

    Wildlife Preserve

    WASTE DISPOSAL, SEWAGE • 7.00 Acres
    Value Estimation by Request
    Wildlife Preserve, Sanibel, FL 33957
    View details
    Bay Dr

    Bay Dr

    WASTE DISPOSAL, SEWAGE • 19.16 Acres
    Value Estimation by Request
    Bay Dr, Sanibel, FL 33957
    View details
    2505 Is Inn Rd

    2505 Is Inn Rd

    WASTE DISPOSAL, SEWAGE • 0.33 Acres
    Value Estimation
    $240,000
    2505 Is Inn Rd, Sanibel, FL 33957
    View details
    Sanibel, FL 33957

    Sanibel, FL 33957

    WASTE DISPOSAL, SEWAGE • 1.00 Acre
    Value Estimation by Request
    Sanibel, FL 33957
    View details
    Sanibel, FL 33957

    Sanibel, FL 33957

    WASTE DISPOSAL, SEWAGE • 11.00 Acres
    Value Estimation by Request
    Sanibel, FL 33957
    View details
    Sanibel, FL 33957

    Sanibel, FL 33957

    WASTE DISPOSAL, SEWAGE • 5.00 Acres
    Value Estimation by Request
    Sanibel, FL 33957
    View details
    1349 Bay Dr

    1349 Bay Dr

    WASTE DISPOSAL, SEWAGE • 0.31 Acres
    Value Estimation
    $5,965,000
    1349 Bay Dr, Sanibel, FL 33957-3513
    View details
    2495 Coconut Dr

    2495 Coconut Dr

    WAREHOUSE, STORAGE • 2,542 SF
    Value Estimation
    $210,000
    2495 Coconut Dr, Sanibel, FL 33957-2007
    View details
    2361 Periwinkle Way

    2361 Periwinkle Way

    MINI-WAREHOUSE, STORAGE • 3,457 SF
    Value Estimation
    $215,000
    2361 Periwinkle Way, Sanibel, FL 33957
    View details

    Sanibel, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 246 commercial real estate investment opportunities in Sanibel, FL with 86 listings featured on our commercial real estate marketplace. The current inventory includes 14,576,830 square feet of properties with an estimated value of $224,874,800.

    Estimated prices for commercial real estate in Sanibel, FL begin at $70,000, with an average of $1,081,128 and extend to $21,000,000.

    In Sanibel, FL, current investment values show:

    • Office Properties & Spaces positioned at $391,925
    • Land measuring $1,782,921
    • Office buildings assessed at $348,606
    • Residential land & home lots calculated at $1,447,403
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    Browse Commercial real estate for Sale Near Sanibel, FL

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    Most Searched ZIP Codes in Sanibel, FL

    • 33957

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