Advertise
    Sanibel, FL
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Sanibel, FL Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Fort Myers Beach, FL Fort Myers, FL Saint James City, FL
    Sanibel Office Space Available
    $22 SF/Yr
    3,226 SF
    Sanibel Office Space Available

    4301 Sanibel Captiva Rd, Sanibel, FL

    Office space available for rent in Sanibel, Florida.
    • Office space available for rent
    • Located in Sanibel, Florida
    Updated: Nov 25, 2025
    View details
    Sanibel Office Space For Rent
    $30 SF/Yr
    1,125 SF
    Sanibel Office Space For Rent

    1530 Periwinkle Way, Sanibel, FL

    Second floor office space available on Periwinkle Way.
    • High visibility location on Periwinkle Way
    • Liberal GC commercial zoning in Sanibel, FL
    • Heavy seasonal and local traffic area
    • 1,125 +/- Sqft of space
    • 2nd floor space with elevator
    Updated: Jan 30, 2025
    View details
    Sanibel Island Retail Space Available
    Contact for pricing
    41,741 SF
    Sanibel Island Retail Space Available

    Grocery-anchored shopping center in the heart of Sanibel Island.

    1700 Periwinkle Way, Sanibel, FL 33957

    View details
    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 3 Active listings in Sanibel, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 22 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    High-Visibility Corner Retail Space
    Contact for pricing
    High-Visibility Corner Retail Space

    Updated commercial building with drive-through and high traffic volume.

    19003 San Carlos Blvd, Fort Myers Beach, FL 33931

    View details
    Prime Retail/Office/Medical Space Available
    Contact for pricing
    2,000 SF
    Prime Retail/Office/Medical Space Available

    Retail, office, and medical spaces with high visibility frontage.

    16681 McGregor Blvd, Fort Myers, FL

    View details
    Move-in Ready Iona Community Office
    Contact for pricing
    2,607 SF
    Move-in Ready Iona Community Office

    2,607± Sq. Ft. office space in a growing corridor.

    16680 McGregor Blvd, Fort Myers, FL 33908

    View details
    Retail Center on San Carlos Boulevard
    Contact for pricing
    1,452 SF
    Retail Center on San Carlos Boulevard

    Retail spaces available in renovated Fort Myers Beach shopping center.

    17260-17284 San Carlos Blvd, Fort Myers Beach, FL

    View details

    Similar Spaces for Sale in Sanibel, FL

    Consider Similar Space for Sale. We found 22 Spaces matching your search parameters.

    Sanibel Commercial Building For Sale
    $2,700,000
    4,066 SF
    Sanibel Commercial Building For Sale

    Income-producing commercial building in Sanibel's Central Business District.

    2440 Palm Ridge Road, Sanibel, FL 33957

    View details
    Sanibel Island Commercial Property
    $1,495,000
    2,827 SF
    Sanibel Island Commercial Property

    Highly visible commercial property in Sanibel's Town Center corridor.

    2341 Palm Ridge Road, Sanibel, FL 33957

    View details
    Corner Office Condominium Suite
    $369,000
    0.14 Acres
    Corner Office Condominium Suite

    Professionally updated office condo with three private offices, reception, and extra windows at the end of a small plaza.

    1640 Periwinkle Way, Sanibel, FL 33957

    View details
    Prime Commercial Lot on Sanibel
    $2,950,000
    1.08 Acres
    Prime Commercial Lot on Sanibel

    High-visibility commercial lot ideal for restaurant, retail, or office.

    1625 Periwinkle Way, Sanibel, FL 33957

    View details
    Refreshed Olde Florida-Style Office
    $1,100,000
    0.04 Acres
    Refreshed Olde Florida-Style Office

    Distinctive office campus with flexible spaces on Sanibel's main artery.

    1149 Periwinkle Way, Sanibel, FL 33957

    View details
    Renovated Office Condo on Sanibel
    $225,000
    987 SF
    Renovated Office Condo on Sanibel

    Completely renovated office condo in the heart of Sanibel Island.

    1640 Periwinkle Way, Sanibel, FL 33957

    View details
    Prime Commercial Space on Periwinkle
    $795,000
    0.04 Acres
    Prime Commercial Space on Periwinkle

    Commercial building with high visibility on a high-traffic island corridor.

    1025 Periwinkle Way, Sanibel, FL 33957

    View details
    Sanibel Boutique Resort Opportunity
    $2,999,000
    1.16 Acres
    Sanibel Boutique Resort Opportunity

    Boutique resort on over an acre near Sanibel beaches.

    1220 Morningside Place, Sanibel, FL 33957

    View details
    Sanibel Commercial/Residential Opportunity
    $1,500,000
    0.50 Acres
    Sanibel Commercial/Residential Opportunity

    Prime 0.498-acre parcel on West Gulf Drive, Sanibel, Florida.

    2761 W Gulf Drive, Sanibel, FL 33957

    View details
    Sanibel Island Commercial Property For Sale
    $1,495,000
    2,827 SF
    Sanibel Island Commercial Property For Sale

    Highly visible commercial property in Sanibel Island's Town Center.

    2341 Palm Ridge Rd A, B, C, Sanibel, FL 33957

    View details
    Elevated Retail and Restaurant Property
    $5,500,000
    3.00 Acres
    Elevated Retail and Restaurant Property

    Elevated retail and restaurant building on Periwinkle Way with over 200 feet of road frontage and General Commercial zoning.

    1551 Periwinkle Way, Sanibel, FL 33957

    View details
    Waterfront Commercial Land Parcel
    $2,999,000
    2.29 Acres
    Waterfront Commercial Land Parcel

    Commercial land with substantial frontage and waterfront features, zoned for General Commercial and D2 Upland Wetland.

    1223 Periwinkle Way, Sanibel, FL 33957

    View details
    Town Center Office Building
    $1,495,000
    Town Center Office Building

    Professionally configured office space with multiple private offices, conference rooms, and ample on-site parking.

    2341 Palm Ridge Road Unit A, B, C, Sanibel, FL 33957

    View details
    Sanibel Commercial Building For Sale
    $1,095,000
    3,000 SF
    Sanibel Commercial Building For Sale

    Commercial building with open floor plan and residential potential.

    905 Fitzhugh Street, Sanibel, FL 33957

    View details
    Established Sanibel Business Opportunity
    $1,200,000
    Established Sanibel Business Opportunity

    Iconic Sanibel business with loyal customer base for sale.

    1551 Periwinkle Way, Sanibel, FL 33957

    View details
    Sanibel Commercial Building with Upside
    $2,700,000
    4,066 SF
    Sanibel Commercial Building with Upside

    Income-producing commercial building with future residential potential in Sanibel, Florida.

    2440 Palm Ridge Rd, Sanibel, FL 33957

    View details
    Sanibel Office Suite For Sale
    $349,000
    Sanibel Office Suite For Sale

    Bright, versatile office suite in central Sanibel location.

    2323 Wooster Ln 1, Sanibel, FL 33957

    View details
    Sanibel Island Motel Opportunity
    $5,300,000
    0.50 Acres
    Sanibel Island Motel Opportunity

    Two Sanibel Island motels with strong rental income.

    706 Donax St, Sanibel, FL 33957

    View details
    Completely Renovated Office Condo
    $225,000
    987 SF
    Completely Renovated Office Condo

    Turnkey, fully renovated office condo with built-in workspaces, multiple offices, and in-unit amenities for professional use.

    3-1640 Periwinkle Way, Sanibel, FL 33957

    View details
    Vanilla Shell Retail Space
    Contact for pricing
    2,500 SF
    Vanilla Shell Retail Space

    Flexible retail units available as a vanilla shell within a shopping center on Sanibel.

    2075 Periwinkle Way, Sanibel, FL 33957

    View details
    Sanibel Homesite on Golf Course
    $539,000
    0.32 Acres
    Sanibel Homesite on Golf Course

    Homesite on Sanibel's east end with golf course views.

    1340 Eagle Run Drive, Sanibel, FL 33957

    View details

    Sanibel, FL Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Sanibel, FL with 3 listings featured on our commercial real estate exchange. The current inventory includes 4,351 square feet of properties with an estimated lease value of $52 SF/Yr.

    Estimated lease rates for Commercial real estate in Sanibel, FL begin at $22 SF/Yr, with an average of $26 SF/Yr and extend to $30 SF/Yr.
    List
    Map

    Browse Commercial real estate for Lease Near Sanibel, FL

    Popular Searches in Sanibel, FL

    Most Searched ZIP Codes in Sanibel, FL

    • 33957

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!