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    Sanibel, FL
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    Sanibel, FL Commercial Real Estate for Lease

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    Miami, FL Orlando, FL Jacksonville, FL
    Sanibel Office Space Available
    $28 SF/Yr
    3,226 SF

    Sanibel Office Space Available

    4301 Sanibel Captiva Rd, Sanibel, FL

    Office space available for rent in Sanibel, Florida.

    • Office space available for rent
    • Located in Sanibel, Florida
    Updated: Nov 25, 2025
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    Sanibel Island Retail Space Available
    Contact for pricing
    41,741 SF

    Sanibel Island Retail Space Available

    1700 Periwinkle Way, Sanibel, FL 33957

    Grocery-anchored shopping center in the heart of Sanibel Island.

    • Grocery anchored shopping center
    • Located in the heart of Sanibel Island’s shopping district
    • Immediate opportunities available
    Updated: Mar 7
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    Sanibel Office Space For Rent
    $30 SF/Yr
    1,125 SF

    Sanibel Office Space For Rent

    Second floor office space available on Periwinkle Way.

    1530 Periwinkle Way, Sanibel, FL
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    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 3 Active listings in Sanibel, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 23 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    High-Visibility Corner Retail Space
    Contact for pricing

    High-Visibility Corner Retail Space

    Updated commercial building with drive-through and high traffic volume.

    19003 San Carlos Blvd, Fort Myers Beach, FL 33931
    View details
    Prime Retail/Office/Medical Space Available
    Contact for pricing
    2,000 SF

    Prime Retail/Office/Medical Space Available

    Retail, office, and medical spaces with high visibility frontage.

    16681 McGregor Blvd, Fort Myers, FL
    View details
    Move-in Ready Iona Community Office
    Contact for pricing
    2,607 SF

    Move-in Ready Iona Community Office

    2,607± Sq. Ft. office space in a growing corridor.

    16680 McGregor Blvd, Fort Myers, FL 33908
    View details
    Retail Center on San Carlos Boulevard
    $20 SF/Yr
    1,452 SF

    Retail Center on San Carlos Boulevard

    Retail spaces available in renovated Fort Myers Beach shopping center.

    17260-17284 San Carlos Blvd, Fort Myers Beach, FL
    View details

    Similar Spaces for Sale in Sanibel, FL

    Consider Similar Space for Sale. We found 23 Spaces matching your search parameters.

    Sanibel Commercial Building For Sale
    $2,700,000
    0.63 Acres

    Sanibel Commercial Building For Sale

    Income-producing commercial building in Sanibel's Central Business District.

    2440 Palm Ridge Road, Sanibel, FL 33957
    View details
    Sanibel Island Office Condo
    $415,000
    0.03 Acres

    Sanibel Island Office Condo

    Turnkey, stabilized office condo on Periwinkle Way, Sanibel Island.

    1101 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Office Suite For Sale
    $329,000
    0.11 Acres

    Sanibel Office Suite For Sale

    Bright, versatile office suite in central Sanibel location.

    2323 Wooster Lane, Sanibel, FL 33957
    View details
    Sanibel Beachfront Development Opportunity
    $11,000,000
    2.86 Acres

    Sanibel Beachfront Development Opportunity

    2.86-acre beachfront property ideal for luxury condominium development.

    2669 W Gulf Drive, Sanibel, FL 33957
    View details
    Prime Commercial Lot on Sanibel
    $2,950,000
    1.08 Acres

    Prime Commercial Lot on Sanibel

    High-visibility commercial lot ideal for restaurant, retail, or office.

    1625 Periwinkle Way, Sanibel, FL 33957
    View details
    Prime Commercial Space on Periwinkle
    $795,000
    0.04 Acres

    Prime Commercial Space on Periwinkle

    Commercial building with high visibility on a high-traffic island corridor.

    1025 Periwinkle Way, Sanibel, FL 33957
    View details
    Refreshed Olde Florida-Style Office
    $1,100,000
    0.04 Acres

    Refreshed Olde Florida-Style Office

    Distinctive office campus with flexible spaces on Sanibel's main artery.

    1149 Periwinkle Way, Sanibel, FL 33957
    View details
    Prime Sanibel Commercial Landmark
    $2,895,000
    0.49 Acres

    Prime Sanibel Commercial Landmark

    Versatile property on Periwinkle Way with retail, residential, and income potential.

    1446 & 1444 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Island Investment Opportunity
    $5,400,000
    0.84 Acres

    Sanibel Island Investment Opportunity

    Income-producing commercial property on Sanibel Island's main corridor.

    1039 & 1041 Periwinkle Way, Sanibel, FL 33957
    View details
    Renovated Office Condo on Sanibel
    $225,000
    0.14 Acres

    Renovated Office Condo on Sanibel

    Completely renovated office condo in the heart of Sanibel Island.

    1640 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Boutique Resort Opportunity
    $2,999,000
    1.16 Acres

    Sanibel Boutique Resort Opportunity

    Boutique resort on over an acre near Sanibel beaches.

    1220 Morningside Place, Sanibel, FL 33957
    View details
    Sanibel Commercial/Residential Opportunity
    $1,500,000
    0.50 Acres

    Sanibel Commercial/Residential Opportunity

    Prime 0.498-acre parcel on West Gulf Drive, Sanibel, Florida.

    2761 W Gulf Drive, Sanibel, FL 33957
    View details
    Sanibel Island Commercial Property
    $1,200,000
    0.49 Acres

    Sanibel Island Commercial Property

    Commercial property on Sanibel Island with frontage on Periwinkle Way.

    1544 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Commercial Building For Sale
    $1,200,000
    0.26 Acres

    Sanibel Commercial Building For Sale

    Commercial building with side street frontage in Sanibel, Florida.

    905 Fitzhugh Street, Sanibel, FL 33957
    View details
    Prime Commercial Property on Periwinkle
    $5,500,000
    3.00 Acres

    Prime Commercial Property on Periwinkle

    Commercial property with excellent exposure and road frontage on 3 acres.

    1551 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Development Opportunity on Periwinkle
    $2,999,000
    2.29 Acres

    Sanibel Development Opportunity on Periwinkle

    Iconic Sanibel property with frontage on Periwinkle Way.

    1223 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Office Suite For Sale
    $349,000

    Sanibel Office Suite For Sale

    Bright, versatile office suite in central Sanibel location.

    2323 Wooster Ln 1, Sanibel, FL 33957
    View details
    Established Sanibel Business Opportunity
    $1,200,000

    Established Sanibel Business Opportunity

    Iconic Sanibel business with loyal customer base for sale.

    1551 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Commercial Building with Upside
    $2,700,000
    4,066 SF

    Sanibel Commercial Building with Upside

    Income-producing commercial building with future residential potential in Sanibel, Florida.

    2440 Palm Ridge Rd, Sanibel, FL 33957
    View details
    Sanibel Island Mixed-Use Development Opportunity
    $4,750,000
    3.82 Acres

    Sanibel Island Mixed-Use Development Opportunity

    Approved development for restaurant and eight residential dwellings in Sanibel.

    2163 & 2153 Periwinkle Way, Sanibel, FL 33957
    View details
    Sanibel Island Motel Opportunity
    $5,300,000
    0.50 Acres

    Sanibel Island Motel Opportunity

    Two Sanibel Island motels with strong rental income.

    706 Donax St, Sanibel, FL 33957
    View details

    Sanibel, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Sanibel, FL with 3 listings featured on our commercial real estate exchange. The current inventory includes 4,351 square feet of properties with an estimated lease value of $58 SF/Yr.

    Estimated lease rates for Commercial real estate in Sanibel, FL begin at $28 SF/Yr, with an average of $29 SF/Yr and extend to $30 SF/Yr.
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