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    Florence, SC
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    Florence, SC Commercial Real Estate for Lease

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    Darlington, SC Timmonsville, SC Hartsville, SC
    Showing 8 of 32 results
    Prime Outparcel Opportunities in Florence
    $1.00 SF/Yr
    Prime Outparcel Opportunities in Florence

    Outparcels available at I-95 interchange, ideal for hotels, restaurants.

    2939 N Williston Rd, Florence, SC 29506

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    Florence Commercial Space For Rent
    Contact for pricing
    Florence Commercial Space For Rent

    Commercial space suitable for office, professional, or retail use.

    2843 W Palmetto Street Suite C, Florence, SC 29501

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    Prime Acreage on West Palmetto
    Contact for pricing
    Prime Acreage on West Palmetto

    Commercial land for rent near Florence Mall and Five Points.

    1609 W Palmetto St, Florence, SC 29501

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    High Traffic Commercial Land ForRent
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    High Traffic Commercial Land ForRent

    0.70 acre lot with high visibility in West Florence.

    Bentree Ln, Florence, SC 29501

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    New Metal Building Near Highways
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    New Metal Building Near Highways

    Newly constructed flex/industrial/office space near major highways.

    2315 Prosperity Way, Florence, SC 29501

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    Retail Space in Florence Mall
    Contact for pricing
    329,000 SF
    Retail Space in Florence Mall

    Prime retail space in regional shopping center, Florence, South Carolina.

    1945 W Palmetto St, Florence, SC 29501

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    Modern Flex Space For Lease
    $11 SF/Yr
    2,450 SF
    Modern Flex Space For Lease

    Flex space with office and warehouse components available for lease.

    1838 Habersham Square, Florence, SC 29501

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    Prestigious Office Suites in Florence
    $25 SF/Yr
    4,453 SF
    Prestigious Office Suites in Florence

    Corporate office suites available for lease in Florence, SC.

    1831 W Evans St, Florence, SC 29501

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    Based on your search, we've compiled 138 Potential Opportunities for your consideration. Besides 32 Active listings in Florence, SC, we suggest exploring alternatives. Consider Similar 102 Spaces for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space Near Walmart
    $26 SF/Yr
    1,200 SF
    Retail Space Near Walmart

    Retail space available February 2026 near Walmart Supercenter.

    1211 Retail Row, Hartsville, SC 29550

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    Retail Strip Center Storefront
    Contact for pricing
    Retail Strip Center Storefront

    1,200 SF storefront for lease in a retail strip center with strong visibility and signage opportunities.

    1217 S FOURTH ST, Hartsville, SC 29550

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    Industrial Space Available For Lease
    Contact for pricing
    9,014 SF
    Industrial Space Available For Lease

    9,014 SqFt industrial space suitable for single tenant.

    941 S Governor Williams Hwy, Darlington, SC 29532

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    Retail Space in Darlington, SC
    Contact for pricing
    6,000 SF
    Retail Space in Darlington, SC

    Retail space available in Darlington, SC, anchored by Planet Fitness.

    508 Lamar Highway, Darlington, SC

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    Similar Spaces for Sale in Florence, SC

    Consider Similar Space for Sale. We found 102 Spaces matching your search parameters.

    Historic Downtown Office Building
    $2,700,000
    16,304 SF
    Historic Downtown Office Building

    Historic office building with multiple suites and ample on-site parking in downtown Florence.

    248-260 W Evans st., Florence, SC 29501

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    Office Property with Parking
    $250,000
    1,405 SF
    Office Property with Parking

    Office space on a 0.31-acre lot with parking and strong visibility along W Palmetto St in Florence.

    2228 W Palmetto St., Florence, SC 29501

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    Remodeled Medical Office Building
    $320,000
    2,165 SF
    Remodeled Medical Office Building

    Turnkey, fully remodeled office building with five rooms and private patient or work-ready treatment configurations.

    910 W Evans st, Florence, SC 29501

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    Fully Occupied Retail Center
    $1,650,000
    15,450 SF
    Fully Occupied Retail Center

    Retail center in good condition with high traffic count.

    823-817 S Cashua Drive, Florence, SC 29501

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    Vacant Specialty Commercial Building
    $265,000
    2,422 SF
    Vacant Specialty Commercial Building

    Vacant specialty building sold as-is, with access via a Sentri lockbox at the back door near a small patio.

    818 S Cashua Drive, Florence, SC 29501

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    Day Care Center For Sale
    $285,000
    2,067 SF
    Day Care Center For Sale

    Existing day care center offered as-is with special showing requirements and lockbox access on the back door.

    822 S Cashua, Florence, SC 29501

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    Buildable Retail Development Land
    $1,500,000
    7.27 Acres
    Buildable Retail Development Land

    Level, buildable two-parcel land package suited for a range of retail and service-oriented development uses.

    3312 Meadors Road, Florence, SC 29501

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    Development-Ready Commercial Land Site
    $980,000
    4.76 Acres
    Development-Ready Commercial Land Site

    4.76-acre B3-zoned parcel on a four-lane corridor with SCDOT-reported traffic near major daily-use anchors.

    917 S Cashua Drive, Florence, SC 29501

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    Commercial Land Opportunity
    $129,900
    4.00 Acres
    Commercial Land Opportunity

    4-acre commercial land in Florence County, positioned in a high-traffic area for a wide range of business uses.

    W Leggs Cir, Florence, SC 29501

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    B-6 Zoned Commercial Land Opportunity
    $47,900
    840 SF
    B-6 Zoned Commercial Land Opportunity

    B-6 zoned parcel suited for a range of commercial development options.

    720 S Barringer Street, Florence, SC 29506

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    Commercial Land with Bus Terminal
    $395,000
    5,500 SF
    Commercial Land with Bus Terminal

    1.05-acre site with 5,500 SF bus terminal building.

    611 S Irby St, Florence, SC 29501

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    Florence Area Investment Opportunity
    Contact for pricing
    Florence Area Investment Opportunity

    Prime land in Florence, SC, with development potential.

    5723 E National Cemetery Rd, Florence, SC 29506

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    Florence Commercial Land For Sale
    $792,792
    1.82 Acres
    Florence Commercial Land For Sale

    1.82 acre commercial land near I-95 in Florence, SC.

    Presbyterian Road, Florence, SC 29501

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    Commercial Corner Land Parcel
    $125,000
    0.10 Acres
    Commercial Corner Land Parcel

    Corner lot in Commercial zoning, suited for buyers looking to develop on a small in-fill site.

    360 N Dargan St, Florence, SC 29501

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    Commercial Property on Pamplico Highway
    $395,000
    0.90 Acres
    Commercial Property on Pamplico Highway

    Approximately 1.2 acre commercial property for sale or lease.

    111 Pamplico Highway, Florence, SC 29501

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    Agricultural Land Tract
    $525,000
    83.54 Acres
    Agricultural Land Tract

    Large agriculturally zoned land available for sale along Timmonsville Highway in the Florence area.

    Timmonsville Hwy, Florence, SC 29532

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