Lancaster, NY Commercial Real Estate for Lease

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East Amherst, NY Buffalo, NY Bowmansville, NY Clarence, NY Elma, NY Queens, NY Orchard Park, NY Alden, NY
71 properties
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Retail Space with Treatment Rooms
Updated: Sep 20
Retail Space with Treatment Rooms

4900 Transit Road, Depew, NY 14043

$36 SF/Yr
2,672 sqft
2672 sq ft retail space facing Transit Road
9 treatment rooms with reception and lounge areas
Includes laundry room, employee lounge, manager's office, and 2 restrooms
Sublease runs through December 31, 2028, subject to landlord approval
Located near the William/Losson corner in Depew/Lancaster
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Modern Coworking Space with Private Offices
Updated: Aug 24
Modern Coworking Space with Private Offices

5775 Broadway St, Lancaster, NY 14086

$600/Mo per office
5,169 sqft
Individual private executive offices within a 5,169‑square‑foot coworking property
Utilities and high‑speed Wi‑Fi included
Shared conference rooms, kitchen, mailbox service, and reception area
Building security with secured private offices
Short‑term arrangements available for accountants and seasonal office users
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Retail Space with Treatment Rooms
Retail Space with Treatment Rooms

4900 suite 300 Transit Road, Cheektowaga, NY 14043

$30 SF/Yr
2,672 sqft

Configured for service-oriented retail with reception, private rooms, office space, and employee support areas.

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Two-Story Office Building
Two-Story Office Building

345 Dick Rd, Depew, NY 14043

$800/Mo
8,922 sqft

Two-level office building with on-site conferencing and 30 surface parking spaces.

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Medical Office Space Available
Medical Office Space Available

4893 Transit Road, Lancaster, NY 14043

$25 SF/Yr
3,004 sqft

3,004 SF medical suite for lease on Transit Road.

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Retail/Office Space on Heavily Trafficked Intersection
Retail/Office Space on Heavily Trafficked Intersection

5102 Genesee Street, Depew, NY 14043

$18 SF/Yr
2,000 sqft

Retail and office spaces available for lease with high visibility.

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Class A Office Sublease
Class A Office Sublease

4455 Genesee Street, Cheektowaga, NY 14225

$21 SF/Yr
8,000 sqft

Class A office space available for sublease in Cheektowaga.

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Versatile Space in Catalyst Fitness Plaza
Versatile Space in Catalyst Fitness Plaza

5087 Broadway, Depew, NY 14043

$12 SF/Yr
23,000 sqft

Medical office, retail, and warehouse spaces available for lease.

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Shopping Center with Pylon Signage
Shopping Center with Pylon Signage

4779 Transit Road, Depew, NY 14043

Contact for pricing
11,600 sqft

Retail strip shopping center on a high-traffic corridor with pylon signage and anchored by Tops Friendly Markets.

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Inline Retail Space with Large Windows
Inline Retail Space with Large Windows

5100 Genesee St, Cheektowaga, NY 14225

Contact for pricing
1,000 sqft

The suite is undergoing a warm vanilla-box update for a range of compact retail concepts.

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Flex Warehouse with Retail and Offices
Flex Warehouse with Retail and Offices

10 W Main St, Lancaster, NY 14086

$8 SF/Yr

Multi-use building offering warehouse, street retail, and office space with two grade-level doors.

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Medical Building with Development Potential
Medical Building with Development Potential

3083 William Street, Cheektowaga, NY 14227

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3,200 sqft

Partially leased medical building with developable lot on William Street.

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Corner Office Suite
Corner Office Suite

6350 Transit Road, Depew, NY 14043

Contact for pricing
11,680 sqft

Office layout includes reception, private offices, open work areas, and conference rooms.

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Corner-Anchored Retail Center
Corner-Anchored Retail Center

2130 Walden Ave, Cheektowaga, NY 14225

Contact for pricing
2,273 sqft

Retail center anchored by Ollie’s Bargain Outlet with pylon signage and ample parking for customer convenience.

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Transit Road Retail Space Available
Transit Road Retail Space Available

5319-5333 Transit Rd, Depew, NY 14043

Contact for pricing
1,200 sqft

Established hair salon location with high visibility and ample parking.

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Flex Space
Flex Space

3944 Broadway, Depew, NY 14043

$15 SF/Yr

Commercial space along Broadway in Depew’s business corridor, surrounded by established businesses, restaurants, and residential neighborhoods.

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Former Convenience Store and Deli
Former Convenience Store and Deli

3035 Genesee Street, Cheektowaga, NY 14225

Contact for pricing
1,500 sqft

1,500 SF space ready for lease on Genesee Street.

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Transit Road Retail/Office Space
Transit Road Retail/Office Space

6348 Transit Road, Cheektowaga, NY 14225

Contact for pricing
1,500 sqft

High-traffic retail/office space available on Transit Road.

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Retail Space on Genesee Street
Retail Space on Genesee Street

3035 Genesee Street, Cheektowaga, NY 14225

Contact for pricing
900 sqft

900+/- SF retail space with high visibility and accessibility.

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Former Salon Space Available
Former Salon Space Available

3035 Genesee Street, Cheektowaga, NY 14225

Contact for pricing
1,500 sqft

Former salon space available for lease with customization options.

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Transit Road Retail Space Available
Transit Road Retail Space Available

6354 Transit Road, Depew, NY 14043

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1,200 sqft

Newly renovated retail space in high-traffic area on Transit Road.

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Specialty Property with Suite Access
Specialty Property with Suite Access

1109 Harlem Rd Ste 2, Cheektowaga, NY 14227

$1,250/Mo

Commercial suite offering 1,665 square feet for lease in Buffalo.

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Office Suite with Conference Room
Office Suite with Conference Room

2320 George Urban Boulevard, Cheektowaga, NY 14043

$1,500/Mo
1,100 sqft

Office suite for lease featuring four private offices, kitchen area, and a large conference room.

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Lancaster Plaza Retail/Warehouse/Office Space
Lancaster Plaza Retail/Warehouse/Office Space

3291 Walden Ave, Lancaster, NY 14043

Contact for pricing
15,611 sqft 2.35 AC lot

Retail, warehouse, and office space available in Lancaster, NY.

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Lancaster, NY Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Lancaster, NY with 71 listings featured on our commercial real estate exchange. The current inventory includes 494,552 square feet of properties with an estimated lease value of $194.94.

Estimated lease rates for Commercial real estate in Lancaster, NY begin at $1.08 SF/Yr, with an average of $17.72 SF/Yr and extend to $36 SF/Yr.
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