Lee County, FL Commercial Real Estate for Lease

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508 properties
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Flex Office/Retail with Overhead Doors
Flex Office/Retail with Overhead Doors

11637 Kelly Rd., Fort Myers, FL 33908

$17 SF/Yr

Flex units combine office and retail space with warehouse areas accessible via overhead garage doors.

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Versatile Office/Warehouse on Large Site
Versatile Office/Warehouse on Large Site

7050 Pennsylvania Street, Fort Myers, FL 33912

$38.82 SF/Yr
5,100 sqft $16,498/Mo

5,100 SF office/warehouse on 2.5 acres, ideal for industrial uses.

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Medical Office Space For Rent
Medical Office Space For Rent

19451 S Tamiami Trl, Fort Myers, FL 33908

$32.50 SF/Yr

Well-maintained medical office space with high visibility and accessibility.

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Move-in Ready Fort Myers Office
Move-in Ready Fort Myers Office

1825 Colonial Boulevard, Fort Myers, FL 33907

$276 SF/Yr

Prime office space in a convenient, highly visible Fort Myers location.

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Industrial Flex Warehouse with Office
Industrial Flex Warehouse with Office

8417 Littleton Rd, North Fort Myers, FL 33903

$12.50 SF/Yr

Industrial flex facility with warehouse space, high ceilings, and an on-site office for operations and administration.

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Fort Myers Warehouse Space Available
Fort Myers Warehouse Space Available

14661 Jetport Loop, Fort Myers, FL 33913

$17.25 SF/Yr
14,766 sqft $21,226/Mo

14,766 sqft warehouse space for lease in Fort Myers.

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Retail and Office Strip Center
Retail and Office Strip Center

1260 NE 8th St, Cape Coral, FL 33909

$26 SF/Yr

Strip center on Pine Island Parkway with ample parking, offering flexible space for retail, service, or office users.

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Specialty Property for Lease
Specialty Property for Lease

27 Cardinal Drive, North Fort Myers, FL 33917

$3,500/Mo

Specialty property available for lease in Lee County, Florida, listed at $3,500.

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Fort Myers Commercial Office Space
Fort Myers Commercial Office Space

18070 S Tamiami Trail, Fort Myers, FL 33908

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Office space for rent in a mixed-use professional plaza.

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Prime Frontage on US 41
Prime Frontage on US 41

27180 Bay Landing Drive, Bonita Springs, FL 34135

$17 SF/Yr
23,251 sqft $32,938/Mo

High-visibility retail and service space between Estero and Naples.

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Retail Space on Del Prado
Retail Space on Del Prado

4515 Del Prado Blvd S, Cape Coral, FL

$15 SF/Yr
4,000 sqft $5,000/Mo

Retail space with high visibility and traffic count.

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Renovated Office Space Near Hospital
Renovated Office Space Near Hospital

14090 Metropolis Avenue, Fort Myers, FL 33912

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Move-in ready medical/business office space near Gulf Coast Hospital.

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Downtown Fort Myers Office Space
Downtown Fort Myers Office Space

2158 Johnson St, Fort Myers, FL 33901

$18 SF/Yr
13,822 sqft $20,733/Mo

Divisible office space in downtown Fort Myers with open layout.

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Sanibel Office Space Available
Sanibel Office Space Available

4301 Sanibel Captiva Rd, Sanibel, FL

$22 SF/Yr
3,226 sqft $5,914/Mo

Office space available for rent in Sanibel, Florida.

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Industrial Warehouse with Outdoor Storage
Industrial Warehouse with Outdoor Storage

6120 Idlewild St, Fort Myers, FL

$20 SF/Yr
5,000 sqft $8,333/Mo

Industrial warehouse for rent with fenced and secured outdoor storage.

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Commercial Land For Rent
Commercial Land For Rent

Saint James City, FL 33956

$1,850/Mo

Commercial land available for rent, construction completion December 2025.

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Retail Space in Cape Coral
Retail Space in Cape Coral

1260 NE Pine Island Rd, Cape Coral, FL

$26 SF/Yr
2,200 sqft $4,766/Mo

Retail space available for rent in Cape Coral, Florida.

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Retail Plaza with Drive-Through Unit
Retail Plaza with Drive-Through Unit

9985 Estero Oaks dr, Fort Myers, FL 33967

$45 SF/Yr

New retail plaza will deliver in January 2026 with six spaces, including a corner unit featuring drive-through access.

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Class A Office and Salon Suites
Class A Office and Salon Suites

3820 COLONIAL Boulevard, Fort Myers, FL 33966

Contact for pricing

Two-story office and salon suite building with elevator service and convenient parking for professional tenants.

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Cape Coral Office/Retail Space
Cape Coral Office/Retail Space

1634 SE 47th St, Cape Coral, FL 33904

$18 SF/Yr
15,675 sqft $23,512/Mo

Exceptional office/retail space in Cape Coral, FL, with ample parking.

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Warehouse Unit with Overhead Door
Warehouse Unit with Overhead Door

Saint James City, FL 33956

$1,550/Mo

Lease a warehouse with a large overhead door, front and rear walk-through doors, and a restroom, plus electric.

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Retail Space Near Edison Mall
Retail Space Near Edison Mall

4380 Cleveland Ave, Fort Myers, FL

$16 SF/Yr
31,200 sqft $41,600/Mo

Retail plaza with frontage on Cleveland Avenue available for lease.

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Class A Office Space Available
Class A Office Space Available

12800 University Dr, Fort Myers, FL

$21 SF/Yr
5,570 sqft $9,747/Mo

Premier office complex in the heart of Lee County.

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Industrial
Industrial

5826 Corporation Cir, Fort Myers, FL 33905

$14.50 SF/Yr
10,000 sqft $12,083/Mo

Warehouses · 10,000 SF

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