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    Lee County, FL Commercial Real Estate for Lease

    524 results
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    Downtown Cape Coral Office Space
    $2,000 / Mo
    6,800 SF

    Downtown Cape Coral Office Space

    1031 Cape Coral Pkwy E 206208, Cape Coral, FL 33904

    Commercial office space for lease in downtown Cape Coral.

    • Prime location on Cape Coral Parkway E in downtown Cape Coral
    • High traffic count area
    • Ample parking available in both front and back of the building
    • Office space approximately 1,000 sq ft
    • Located on the second floor
    Updated: Nov 28, 2025
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    Fort Myers Warehouse and Office
    Contact for pricing
    174,240 SF

    Fort Myers Warehouse and Office

    6830 Buckingham Rd, Fort Myers, FL 33905

    Two buildings totaling 5,200 SF available December 2025.

    • Two buildings totaling 5,200 sq ft with flexible rental options (4,000 sq ft or 5,200 sq ft).
    • Zoned for Agriculture 2 on 14 acres.
    • Three drive‑in bays in the 4,000 sq ft building and two drive‑in bays in the 1,200 sq ft building.
    • 3‑Phase electric power.
    • Maintenance and property taxes covered by the owner.
    Updated: Dec 10, 2025
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    High-Traffic Retail Space Available
    Contact for pricing
    49,833 SF

    High-Traffic Retail Space Available

    Prime commercial space in North Fort Myers' active commercial corridor.

    710 Pondella Rd, North Fort Myers, FL 33903
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    Office Space in Cape Coral
    $1,000 / Mo
    7,100 SF

    Office Space in Cape Coral

    Spacious office space in the heart of downtown Cape Coral.

    4705 Vincennes Blvd, Cape Coral, FL 33904
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    Cape Coral Flex Warehouse Space
    $1,931 / Mo
    13,199 SF

    Cape Coral Flex Warehouse Space

    Flex office warehouse space, centrally located, easy access.

    326 NE 3Rd Ave, Cape Coral, FL 33909
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    Move-In Ready Fort Myers Office
    $14 SF/Yr
    11,665 SF

    Move-In Ready Fort Myers Office

    1,400 SF office space with flexible lease terms.

    3949 Evans Ave, Fort Myers, FL 33901
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    Mixed-Use Property in Cape Coral
    $5,742 / Mo
    12,502 SF

    Mixed-Use Property in Cape Coral

    Mixed-use property in fast-growing downtown Cape Coral for rent.

    1520 SE 46Th Ln, Cape Coral, FL 33904
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    Fort Myers Office Space Available
    $3,600 / Mo
    5,619 SF

    Fort Myers Office Space Available

    Office space in a calm, accessible Fort Myers location.

    12734 Kenwood Ln, Fort Myers, FL 33907
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    Office Space in Fort Myers
    Contact for pricing
    117,873 SF

    Office Space in Fort Myers

    Office space with easy access and included CAM.

    5929 Youngquist Rd, Fort Myers, FL 33912
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    Lehigh Acres Commercial Space Available
    Contact for pricing
    72,310 SF

    Lehigh Acres Commercial Space Available

    Office space for rent in a growing Lehigh Acres area.

    1120 Village Lakes Blvd, Lehigh Acres, FL 33972
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    Fort Myers Commercial Space Available
    $16 SF/Yr
    19,741 SF

    Fort Myers Commercial Space Available

    Office and warehouse space with fenced yard and truck-well.

    17251 Alico Center Rd, Fort Myers, FL 33967
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    Move-in Ready Fort Myers Office
    $57,500
    22,390 SF

    Move-in Ready Fort Myers Office

    Prime office space in a convenient Fort Myers location.

    1825 Colonial Blvd, Fort Myers, FL 33907
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    Updated Retail/Office Space Available
    $3,458 / Mo
    31,141 SF

    Updated Retail/Office Space Available

    Updated commercial space with showroom, workspace, and flexible zoning.

    18070 S Tamiami Trl, Fort Myers, FL 33908
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    North Fort Myers Commercial Space
    $1,000 / Mo
    21,257 SF

    North Fort Myers Commercial Space

    Commercial space for rent in North Fort Myers, Florida.

    583 Pondella Rd, North Fort Myers, FL 33903
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    Fort Myers Office Space Available
    Contact for pricing
    30,501 SF

    Fort Myers Office Space Available

    Two office suites available in Fort Myers, move-in ready.

    6300 Corporate Ct, Fort Myers, FL 33919
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    Professional Office Space on McGregor
    $4,019 / Mo
    4,073 SF

    Professional Office Space on McGregor

    Move-in-ready office space in well-maintained Fort Myers building.

    2080 Mcgregor Blvd, Fort Myers, FL 33901
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    Professional Office Suites Available
    Contact for pricing

    Professional Office Suites Available

    Executive suites and office spaces in Fort Myers, Florida.

    1500 Colonial Blvd, Fort Myers, FL 33907
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    Class A Office Suites Available
    $565 / Mo
    43,560 SF

    Class A Office Suites Available

    Executive suites with included amenities in a prime location.

    4706 Chiquita Blvd S, Cape Coral, FL 33914
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    Cape Coral Office Space Available
    $2,500 / Mo
    31,873 SF

    Cape Coral Office Space Available

    Well-maintained office building in a convenient Cape Coral location.

    840 SW 4Th St, Cape Coral, FL 33991
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    Cape Coral Office Space Available
    $1,950 / Mo
    48,961 SF

    Cape Coral Office Space Available

    Two office spaces available, one with gulf access canal view.

    2804 Del Prado Blvd S, Cape Coral, FL 33904
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    Fort Myers Office Space Available
    Contact for pricing
    38,755 SF

    Fort Myers Office Space Available

    Class "B" office building ideal for medical or professional use.

    13515 Bell Tower Dr, Fort Myers, FL 33907
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    Move-in Ready Fort Myers Office
    $2,500 / Mo
    6,168 SF

    Move-in Ready Fort Myers Office

    Office space in a convenient Fort Myers location, move-in ready.

    6226 Presidential Ct, Fort Myers, FL 33919
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    Turnkey Office Spaces in Fort Myers
    Contact for pricing
    30,013 SF

    Turnkey Office Spaces in Fort Myers

    Remodeled office spaces for lease with utilities included.

    6241 Arc Way, Fort Myers, FL 33966
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    Retail Space in Cape Coral
    $3,500 / Mo
    6,839 SF

    Retail Space in Cape Coral

    Retail space available with signage on Cape Coral Parkway.

    1025 Cape Coral Pkwy E, Cape Coral, FL 33904
    View details

    Lee County, FL Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Lee County, FL with 1004 listings featured on our commercial real estate exchange. The current inventory includes 350,265,382,006 square feet of properties with an estimated lease value of $286,465.

    Estimated lease rates for Commercial Real Estate in Lee County, FL begin at $0.56 SF/Yr, with an average of $918 /Mo and extend to $217,200.

    In Lee County, FL, current lease rates show:

    • Office Properties & Spaces positioned at $1,735
    • Office space measuring $520
    • Industrial properties assessed at $44
    • Retail properties calculated at $20
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