Lee County, FL Commercial Real Estate for Lease

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568 properties
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Renovated Office Unit
Renovated Office Unit

1416 Lafayette Street, Cape Coral, FL 33904

$1,600/Mo
0.21 AC lot

Unit 2 combines a reception area, private restroom, and separate air-conditioned rear workspace or storage area.

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Climate-Controlled Flex Space
Climate-Controlled Flex Space

12165 Metro PKWY, Fort Myers, FL 33966

$5,000/Mo
4.40 AC lot

Move-in-ready space with grade-level loading, full air conditioning, and IPD zoning.

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Medical Office Space Near Healthcare Providers
Medical Office Space Near Healthcare Providers

13195 Metro Parkway, Fort Myers, FL 33966

$3,250/Mo
2.74 AC lot

Located within a healthcare corridor with access to Colonial Boulevard and Daniels Parkway.

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Improved Retail Space
Improved Retail Space

15881 S Tamiami Trl, Fort Myers, FL 33908

$18 SF/Yr
2,962 sqft

Fully improved retail units with prominent signage along Tamiami Trail, supporting customer-facing business use.

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Remodeled Corner Office Suite
Remodeled Corner Office Suite

2801 Estero Boulevard, Fort Myers Beach, FL 33931

$4,500/Mo
1.12 AC lot

Office suite at Sea Grape Plaza with natural light, Gulf water views, and on-site parking.

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Conventional Restaurant with FF&E
Conventional Restaurant with FF&E

2275 Winkler Avenue, Fort Myers, FL 33901

$60,000/Mo
7.88 AC lot

Existing equipment, furniture, and fixtures are included with this restaurant property.

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Flex Space with Warehouse Doors
Flex Space with Warehouse Doors

954 Country Club Boulevard, Cape Coral, FL 33990

$4,150/Mo
0.42 AC lot

Includes office rooms, a conference room, and open warehouse space.

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Renovated Second-Floor Office Units
Renovated Second-Floor Office Units

2401 1st Street 202a - 203b, Fort Myers, FL 33901

$16 SF/Yr
2,475 sqft

Modern professional space offers enclosed offices, a finished break room, natural light, and separate elevator and stair access.

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Office Suite With Conference Room
Office Suite With Conference Room

3403 Hancock Bridge Parkway, North Fort Myers, FL 33903

$1,550/Mo
0.09 AC lot

Two private offices and shared meeting space provide a practical setting for professional business operations.

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First-Floor Office Unit
First-Floor Office Unit

2400 1st Street, Fort Myers, FL 33901

$5,850/Mo
0.74 AC lot

Large windows and a front porch provide natural light and outdoor workspace.

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Renovated Flex Unit with Garage
Renovated Flex Unit with Garage

2700 Evans Ave 3, Fort Myers, FL 33901

$3,500/Mo
1,050 sqft

Two-story commercial space with offices, restrooms, garage access, and parking improvements in a heavy-industrial zoning district.

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Flex Space with Loading Access
Flex Space with Loading Access

3366 Cleveland Avenue, Fort Myers, FL 33901

$5,900/Mo
0.15 AC lot

CI-zoned commercial building combines retail, office, showroom, storage, and warehouse areas.

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New Retail Space in Alico L7 Plaza
New Retail Space in Alico L7 Plaza

8156 Alico Rd, Fort Myers, FL 33912

$35 SF/Yr
2.00 AC lot

Vanilla-shell units offer flexible layouts with central heating and air conditioning.

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Office Unit with Roll Doors
Office Unit with Roll Doors

12644 Palm Beach Blvd., Fort Myers, FL 33905

$25 SF/Yr
1,360 sqft

Functional office layout with storage, rear roll doors, and access to Palm Beach Boulevard.

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Office Units Near Midpoint Bridge
Office Units Near Midpoint Bridge

2930 Del Prado Boulevard S, Cape Coral, FL 33904

$1,575/Mo
0.34 AC lot

Cape Coral office space along Del Prado Boulevard S, positioned south of the Midpoint Bridge.

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Renovation-Ready Office Unit
Renovation-Ready Office Unit

40 Barkley Circle, Fort Myers, FL 33919

$16 SF/Yr
2.86 AC lot

Single-level office space with NC zoning, shared parking, and recently installed metal roofs across the property.

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Renovated Flex Industrial Building
Renovated Flex Industrial Building

1002 SE 9th St, Cape Coral, FL 33990

$18 SF/Yr
4,500 sqft

Light industrial space with updated offices, three-phase power, and a paved, fenced area for parking or outside storage.

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Office Unit Near Gulf Coast Hospital
Office Unit Near Gulf Coast Hospital

6150 Diamond Centre Court, Fort Myers, FL 33912

$23 SF/Yr
0.09 AC lot

Office space in South Fort Myers with convenient access to US-41 and Daniels Parkway.

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Second-Floor Office Unit
Second-Floor Office Unit

923 Del Prado Boulevard S Unit 203, Cape Coral, FL 33990

$2,450/Mo
1,015 sqft

Configured with private offices, a conference room, reception area, kitchenette, and storage.

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Modern Office Space in Downtown
Modern Office Space in Downtown

2401 1st Street, Fort Myers, FL 33901

$16 SF/Yr
2,475 sqft 0.29 AC lot

Newly renovated office space in the Fort Myers River District.

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Office Suites with Canal Views
Office Suites with Canal Views

2804 Del Prado Boulevard S Unit 106, Cape Coral, FL 33904

$1,975/Mo
1,000 sqft

Two professional office units offer distinct layouts across the first and second floors of a 1986 commercial building.

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Grey-Shell Medical Office Space
Grey-Shell Medical Office Space

11380 Bonita Beach Road SE, Bonita Springs, FL 34135

$3,362/Mo
0.82 AC lot

Unfinished medical office suite available now within a 2019 commercial building on Bonita Beach Road.

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Retail Space in Merchants Plaza
Retail Space in Merchants Plaza

159 Hancock Bridge Parkway 8-10, Cape Coral, FL 33990

$22 SF/Yr
3,200 sqft

3,200 sq ft retail space available February 2026.

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Vanilla-Shell Retail Space
Vanilla-Shell Retail Space

8156 Alico Rd, Fort Myers, FL 33912

$35 SF/Yr
2.00 AC lot

Units feature flexible layouts, vanilla-shell delivery, and central air conditioning for a range of commercial users.

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