Cameron County, TX Office Spaces for sale

Updated: Jun 12

Multi-Suite Rehabilitation Center

8002 W Expressway 83, Harlingen, TX 78552

$1,089,530

7,514 sqft 0.67 AC lot

7,514‑square‑foot commercial building on a 0.6667‑acre site
Four suites, including a contiguous space exceeding 5,000 square feet
Current medical rehabilitation configuration
Frontage‑road access along Expressway 83
Accessible approach with ramp

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Updated: Jun 24

Mixed-Use Property with Atrium Views

1801-1805 E HARRISON AVE., Harlingen, TX 78550

$350,000

3,465 sqft 0.30 AC lot

3,465 square feet on a 0.2984‑acre parcel
Separate office and apartment‑style residential areas
Two treatment rooms with floor‑to‑ceiling windows overlooking an atrium‑style setting
Office includes reception, private office, storage, 2 bathrooms, breakroom, and laundry room
Front and rear parking plus a 2‑car garage

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Medical Office with Treatment Rooms

1100 W TYLER AVE., Harlingen, TX 78550

$695,000

5,161 sqft 0.48 AC lot

Configured with patient rooms, procedure space, labs, offices, storage, and multiple restrooms.

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Freestanding Warehouse with Grade-Level Doors

6201 Fm 106 Unit 17, Harlingen, TX 78550

$1,750,000

19,800 sqft 2.25 AC lot

Newly constructed industrial facility combines dedicated offices with warehouse operations.

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Retail Space Near Downtown

605 E TYLER AVE., Harlingen, TX 78550

$185,000

1,272 sqft 0.16 AC lot

Existing commercial space suited to retail or office use on E Tyler Ave.

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Two-Story Medical Office Building

1024 E Los Ebanos Blvd., Brownsville, TX 78520

$1,999,999

10,441 sqft 1.06 AC lot

Remodeled, the property offers adaptable space for single- or multi-tenant occupancy.

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Office Units Near Hospital

2701 S SUNSHINE STRIP, Harlingen, TX 78550

$1,350,000

14,400 sqft 1.38 AC lot

Corner-lot office property with substantial parking and proximity to Valley Baptist Hospital.

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Condominium Office with Parking

1906 Tyler Avenue, Suite B, Harlingen, TX 78550

$775,000

6,400 sqft

A well-maintained office condominium offering 2,750 SF for lease or owner-occupancy with ample parking.

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Harlingen Office Building For Sale

2420 E Tyler Ave., Harlingen, TX 78550

$1,725,000

11,707 sqft

Exceptional office building in thriving Rio Grande Valley market.

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Multi-Tenant Medical Retail Center

3777 Frontage Rd, Brownsville, TX 78520

$3,800,000

10,563 sqft 1.08 AC lot

Las Palmas Plaza is a 2017 multi-tenant center anchored by healthcare-oriented tenants on NNN lease structures.

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Commercial Land with Office Building

2625 Spur 54, Harlingen, TX 78550

$2,200,000

4,000 sqft

General Retail zoning accommodates retail, dining, lodging, office, and other commercial uses.

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Multi-Suite Office Building

700 E Levee St., Brownsville, TX 78520

$1,500,000

23,302 sqft

Downtown professional office property with elevator access, skylights, and dedicated parking.

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Flex Space Office/Warehouse Campus

4905-4933 E Grimes St, Harlingen, TX 78550

$3,100,000

30,162 sqft 20.00 AC lot

Single-story concrete building offers leased offices, vacant office space, warehouse area, and recently updated HVAC systems.

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Remodeled Medical Center For Sale

1024 E Los Ebanos Blvd, Brownsville, TX 78520

$1,999,999

10,441 sqft 1.00 AC lot

Two-story medical building in established medical district with flexible space.

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Corner Flex Building with Storefront

925 S 77 SUNSHINE STRIP, Harlingen, TX 78550

$365,000

2,200 sqft

The building combines retail frontage with offices and rear warehouse space.

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Medical Office Building with Multiple Entrances

702 S Ed Carey, Harlingen, TX 78550

$1,607,900

16,079 sqft 1.21 AC lot

Multi-suite medical office property with separate foyer entrances and flexible open areas.

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Corner Office Building

1002 E Taylor St, Brownsville, TX 78520

$385,000

3,372 sqft

Well-maintained office property with private offices, conference rooms, and a dedicated storage attic.

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Freestanding Office Building

1060 Mackintosh Drive, Brownsville, TX 78521

$1,600,000

18,320 sqft 2.25 AC lot

Free-standing office building with a lobby, reception, file and break rooms, plus secured parking via electric gate.

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Medical Office with Treatment Rooms

2744 Southmost Rd., Brownsville, TX 78526

$375,000

1,848 sqft

Established healthcare facility with a reception area, private clinical rooms, support areas, and ADA-accessible restroom.

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C-2 Live-Work Space

990 N Dick Dowling St., San Benito, TX 78586

$155,000

1,040 sqft

Updated commercial property with residential-style rooms, two lots, and room for parking or future expansion.

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Restaurant and Office in San Benito

267 W Robertson St., San Benito, TX 78586

$234,000

1,796 sqft

Turnkey restaurant and office space in a high-traffic area.

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Mixed-Use Property with Warehouse

9345 Hwy 281, Brownsville, TX 78520

$495,000

1,554 sqft

Commercial warehouse and brick veneer residence connected by a long paved drive, supporting combined business and residential use.

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Professional Office Unit

1906 E Tyler Ave. Unit G, Harlingen, TX 78550

$415,000

3,000 sqft

Multi-room office configuration within a gated business community, with dedicated areas for meetings, reception, technology, and staff support.

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Highly Visible Office Building

1600 W University Blvd., Brownsville, TX 78520

$1,200,000

0.61 AC lot

Prominent University Blvd frontage and convenient access make this office property a strong fit for owner-occupants or flexible reuses.

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Cameron County, TX Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Cameron County, TX, showcased through 48 active listings on our real estate platform. These investment opportunities span a total of 411,754 square feet of properties for sale, with an estimated market value of $31,851,428.

Sale prices for office properties in Cameron County, TX start at $155,000, averaging $1,098,325, and reaching up to $3,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Featured Cameron County Real Estate Agencies

Realmo connects you with licensed Cameron County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Lower Rio Grande Valley

1713 E Tyler Ste A Harlingen, TX 78550

Phone: 19564238877

Harlingen Homes

1201 E Harrison Ave Harlingen, TX 78550

Phone: 19564235300