Mixed-Use

Cameron County, TX Mixed-use Properties for Sale

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Medical Office with Apartment
Updated: Jun 19
Medical Office with Apartment

1801-1805 E HARRISON AVE., Harlingen, TX 78550

$350,000
3,465 sqft
Mixed‑use property built in 1984 with an office wing and an apartment‑style living space
Office setup includes a reception/waiting room, front desk, private office, 2 treatment rooms, breakroom and laundry room
Office area features 2 bathrooms and includes storage, plus two treatment rooms with floor‑to‑ceiling picture windows overlooking an atrium‑style setting
Residential side offers a large living area, kitchen, bedroom and a full bathroom
Ample parking with 9 parking spaces plus additional rear parking, and a 2‑car garage
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1801-1805 E HARRISON AVE., Harlingen, TX 78550

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Truck Stop With Trailer Yard
Updated: Jan 21
Truck Stop With Trailer Yard

2011 S INDIANA AVE., Brownsville, TX 78521

$1,600,000
2,960 sqft 10.00 AC lot
10‑acre truck stop property with multiple buildings and heavy‑truck site improvements
Primary concrete‑block building includes two offices, break room, and shop with 17 ft clear height
Separate building provides reception area, two offices, and full bathroom
Three‑bedroom, two‑bath residential home included on the property
900 ft concrete slab, 3 ft wide and 6 inches thick, for drop‑loaded trailers
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Waterfront Mixed-Use Hospitality Property
Waterfront Mixed-Use Hospitality Property

418 W Highway 100, Port Isabel, TX 78578

$9,000,000
25,257 sqft 4.47 AC lot

Waterfront asset combining lodging, apartments, marina services, dining, and RV and boat storage.

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Mixed-Use Property with Residential Component
Mixed-Use Property with Residential Component

406 N EXPRESSWAY 77, Harlingen, TX 78550

$418,000
560 sqft 2.00 AC lot

Updated residential improvements are combined with adaptable areas suited for commercial rental use.

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Mixed-Use Plaza with Flexible Layout
Mixed-Use Plaza with Flexible Layout

325 Kings Hwy. Unit 3, Brownsville, TX 78521

$579,900
3,366 sqft

Former daycare facility with multiple interior areas and potential office or retail applications.

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Two-Story Mixed-Use Property
Two-Story Mixed-Use Property

901 S WILLIAMS AVE., San Benito, TX 78586

$740,000
4,375 sqft 0.95 AC lot

Corner-lot commercial property combines office, warehouse, paved yard, and residential space within a fully secured site.

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Mixed-Use Building
Mixed-Use Building

5508 Padre Blvd., South Padre Island, TX 78597

$1,250,000
3,964 sqft 0.20 AC lot

The 2009 building is zoned PBC and identified for multiple uses.

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Three-Lot Commercial Land
Three-Lot Commercial Land

4909 Padre Blvd. lot: 4,5,6, South Padre Island, TX 78597

$699,000
0.57 AC lot

Three connected lots extend across Padre Boulevard and Aries with Comm zoning and cable availability.

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Mixed-Use Restaurant Property
Mixed-Use Restaurant Property

1155 MINNESOTA AVE., Brownsville, TX 78521

$349,900
2,016 sqft

Operating restaurant with an upstairs studio apartment provides both commercial and residential components.

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Multi-Tenant Mixed-Use Commercial Property
Multi-Tenant Mixed-Use Commercial Property

3613 Hwy 83, Harlingen, TX 78552

$2,450,000
4,400 sqft 4.19 AC lot

Multi-use commercial property with leased retail, service, fitness, residential, storage, and parking components.

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Mixed-Use Property with 24 Apartments
Mixed-Use Property with 24 Apartments

2100 Old Port Isabel Rd., Brownsville, TX 78526

$2,700,000
20,000 sqft

Fully leased asset combines multifamily housing with two road-facing commercial buildings.

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Downtown Brownsville Historic Mixed-Use Property
Downtown Brownsville Historic Mixed-Use Property

25 Elizabeth St., Brownsville, TX 78520

$250,000
0.20 AC lot

Historic downtown Brownsville property with investment potential.

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High-Visibility Office Space Available
High-Visibility Office Space Available

185 Ruben M Torres Blvd, Brownsville, TX 78520

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7,554 sqft

Office space in high-traffic retail and business corridor.

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Updated Mixed-Use Property
Updated Mixed-Use Property

406 N Expressway 77, Harlingen, TX 78550

$418,000
560 sqft

Main residence includes additional flexible areas identified for commercial rental use.

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Mixed-Use Property with Retail Center
Mixed-Use Property with Retail Center

1109 N 7th St, Harlingen, TX 78550

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59,777 sqft

38 units with retail, value-add potential in high-traffic area.

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Mixed Use, Office, Retail, Special Purpose
Mixed Use, Office, Retail, Special Purpose

744 E Washington St, Brownsville, TX 78520

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19,690 sqft

Mixed-use properties · 19,690 SF

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Mixed-Use Building with Offices
Mixed-Use Building with Offices

26888 Baker Potts Rd, Harlingen, TX 78552

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7,000 sqft

Flexible commercial layout with office, restroom, kitchenette, and storage areas.

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Remodeled Mixed-Use Property
Remodeled Mixed-Use Property

222 N Main, Santa Rosa, TX 78593

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2,638 sqft 0.12 AC lot

Combines a leased apartment with multi-use office space on a corner lot.

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Mixed-Use Building with Kitchenettes
Mixed-Use Building with Kitchenettes

508 COMMERCE ST., Harlingen, TX 78550

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8,400 sqft

Flexible mixed-use building with commercial and multifamily configuration potential near downtown.

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Fully Occupied Mixed-Use Retail Office
Fully Occupied Mixed-Use Retail Office

2353 Old Port Isabel Road, Brownsville, TX 78521

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Corner mixed-use property with an operating Bar & Grill and a fully leased office building.

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High-Visibility Corner Redevelopment Opportunity
High-Visibility Corner Redevelopment Opportunity

408 W Tyler Ave., Harlingen, TX 78550

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Prime corner location with income, ideal for redevelopment or investment.

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Mixed-Use Building with Apartments
Mixed-Use Building with Apartments

4000 Padre Blvd., South Padre Island, TX 78597

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Single-building property combines commercial space with six separate apartment units under long-term leases.

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Auto Shop with Apartment
Auto Shop with Apartment

264 US HIGHWAY 281, Brownsville, TX 78520

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Automotive service property with a paint and body shop and an upper-level apartment currently in use.

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Mixed-Use Property with Apartment
Mixed-Use Property with Apartment

216 OCEAN BLVD., Los Fresnos, TX 78566

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Office, residential, and apartment components support combined work and living uses.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 24 Active Listings in Cameron County, TX, we suggest to view alternatives - similar 1 Off-Market properties to explore as potential leads.

Cameron County, TX Mixed-Use Properties Market Trends and Statistics

Explore 25 mixed-use properties for sale in Cameron County, TX, showcased through 24 active listings on our real estate platform. These investment opportunities span a total of 175,982 square feet of properties for sale, with an estimated market value of $20,804,800.

Sale prices for multi use buildings in Cameron County, TX start at $250,000, averaging $1,600,369, and reaching up to $9,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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