Cameron County, TX Commercial real estate for Rent & Lease

Updated: Sep 24

Second-Floor Medical Office Space

1204 E Los Ebanos Blvd., Brownsville, TX 78520

$4,500/Mo

3,437 sqft

3,437 square feet of second‑floor medical office space
On‑site parking
First‑floor medical occupancy
Zoned C
Building constructed in 1983

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Updated: Aug 10

Restaurant with Commercial Kitchen

422 N L Street, Harlingen, TX 78550

$3,500/Mo

2,708 sqft 0.50 AC lot

2,708 square feet on a 0.4959‑acre site
Commercial kitchen with griddle, fryer, grill, refrigerator, and freezer
Three‑compartment sink and cold prep table included
POS system, shelves, racks, storage, and televisions remain
Built in 2006 with off‑street parking

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Renovated Flex Space

1683 W Highway 100, Port Isabel, TX 78578

$4,500/Mo

3,984 sqft 0.29 AC lot

Renovated commercial facility suited to retail, office, medical clinic, or restaurant operations.

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Corner Office Building with Conference Rooms

1002 E Taylor St, Brownsville, TX 78520

$2,900/Mo

3,372 sqft

Professional office property with private work areas, meeting rooms, support spaces, and a convenient downtown-adjacent setting.

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Mixed-Use Business Park

2811 W Expressway 83, La Feria, TX 78559

$1,875/Mo

66,000 sqft 24.55 AC lot

Established commercial campus with multiple service-oriented occupants and direct access from the expressway corridor.

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Mixed-Use Business Park

2803 W Expressway 83, La Feria, TX 78559

$3,275/Mo

66,000 sqft 24.55 AC lot

Multi-tenant commercial setting with expressway access, frontage access, and a varied mix of business services.

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Adaptable Specialty Property

5508 Padre Blvd., South Padre Island, TX 78597

$3,500/Mo

1,982 sqft 0.20 AC lot

The owner is open to improvements for a long-term lease, with room configuration that can be adapted for office use.

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Office Unit with Dual Access

1300 E Harrison Ave, Harlingen, TX 78550

$5,000/Mo

4,070 sqft

Former medical-office configuration with professional, medical, and commercial use potential.

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3-Unit Warehouse Space

1501 N 28TH ST., Harlingen, TX 78550

$1.00 SF/Yr

1,375 sqft 1.43 AC lot

Lease-ready warehouse units with overhead doors, dedicated entry doors, and parking for work vehicles.

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Restaurant Space with Outdoor Dining

4001 Padre Blvd., South Padre Island, TX 78597

$6,853/Mo

5,482 sqft 0.57 AC lot

Existing restaurant premises with outdoor dining, commercial zoning, and a location along Padre Boulevard.

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Professional Office Units

A-1911 Lubbock St, Harlingen, TX 78550

$3,500/Mo

2,500 sqft

Office space near Valley Baptist Medical Center with paved off-street parking and flexible professional-use potential.

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Specialty Commercial Property

5508 Padre Blvd., South Padre Island, TX 78597

$3,500/Mo

1,980 sqft 0.20 AC lot

The ground-floor space is available on its own or in combination with the upstairs unit.

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Commercial Land with Storage

FM 511, Brownsville, TX 78526

$3,500/Mo

304,920 sqft 7.00 AC lot

Seven-acre commercial land offering storage space and access from FM 511 near major highways.

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Multi-Use Retail and Distribution Building

110 S Rangerville Rd, Harlingen, TX 78552

$12 SF/Yr

9,270 sqft 1.21 AC lot

A flexible building on acreage with expressway access nearby and options for retail, service, showroom, distribution, or owner-user.

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Flex Space at Business Park

2807 W Expressway 83, La Feria, TX 78559

$1,250/Mo

66,000 sqft 24.55 AC lot

Flexible commercial space in a multi-tenant business park with frontage access and light industrial suitability.

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Office Unit Near Expressway

2312 S Expressway 83, Harlingen, TX 78552

$1,200/Mo

1,190 sqft 1.73 AC lot

Professional office space with an accessible approach and ramp access.

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Downtown Retail Space

1240 A E Elizabeth St., Brownsville, TX 78520

$2,500/Mo

2,500 sqft

Retail leasing opportunity in a downtown Brownsville building with a substantial commercial footprint.

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Corner Office Unit with Consultation Rooms

5636 SOUTHMOST RD., Brownsville, TX 78521

Contact for pricing

3,500 sqft 1.07 AC lot

Configured with reception, lobby, private rooms, records space, and accessible restrooms.

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Medical Office with Exam Rooms

2014 Pease St., Harlingen, TX 78550

$4,500/Mo

3,844 sqft

Configured healthcare space with patient reception, clinical rooms, laboratory area, and dedicated parking.

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Multi-Suite Office Units

4405 Padre Blvd., South Padre Island, TX 78597

$8,000/Mo

3,360 sqft 62.60 AC lot

Flexible office layout with reception, meeting rooms, kitchen, restroom, and customer and employee parking.

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Freestanding Flex Space with Drive-Through

17745 W Expressway 83, Harlingen, TX 78555

$3,000/Mo

3,473 sqft

Mixed office and service layout with a gated yard and oversized overhead doors.

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Palm Boulevard Storefront Space

824 PALM BLVD., Brownsville, TX 78521

Contact for pricing

1,384 sqft 0.28 AC lot

Interior cabinetry and storage complement an accessible entrance and dedicated on-site parking.

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Mixed-Use Building with Apartment

900 E Levee St., Brownsville, TX 78520

$2,500/Mo

4,129 sqft

Retail and warehouse space is paired with an upstairs residential unit and separate street access.

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Corner Office Unit with Bus Access

5636 SOUTHMOST RD., Brownsville, TX 78521

Contact for pricing

1,000 sqft 1.07 AC lot

Flexible office suite suited to medical, dental, and professional office uses.

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Cameron County, TX Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Cameron County, TX with 185 listings featured on our commercial real estate exchange. The current inventory includes 2,464,121 square feet of properties with an estimated lease value of $1,173.

Estimated lease rates for Commercial real estate in Cameron County, TX begin at $2.88 SF/Yr, with an average of $16.53 SF/Yr and extend to $73.49 SF/Yr.