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    Cameron County, TX Medical Office Space for Lease

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    Renovated Flex Facility
    Updated: Sep 2
    Renovated Flex Facility

    1683 W Highway 100, Port Isabel, TX 78578

    $4,500/Mo
    3,984 sqft 0.29 AC lot
    3,984‑square‑foot flex facility
    Recently renovated commercial space
    Fully paved 0.293‑acre lot
    Located along Highway 100 in Port Isabel
    Built in 2003
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    Multi-Suite Office Units
    Updated: Jul 29, 2025
    Multi-Suite Office Units

    4405 Padre Blvd., South Padre Island, TX 78597

    $8,000/Mo
    3,360 sqft 62.60 AC lot
    3,360 SF office property built in 1980
    Multiple offices with varied sizes
    Reception area, conference rooms, kitchen, and public restroom
    Commercial zoning identified as Comm
    Customer parking in front, plus additional parking behind and in another lot
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    Gallery Walk Retail Space
    Gallery Walk Retail Space

    FM 802, Brownsville, TX 78526

    $2,107/Mo
    980 sqft 0.24 AC lot

    Retail space supporting office, medical, restaurant, spa, and clothing-related uses within a commercial setting.

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    Freestanding Flex Space with Drive-Through
    Freestanding Flex Space with Drive-Through

    17745 W Expressway 83, Harlingen, TX 78555

    $3,000/Mo
    3,473 sqft

    Mixed office and service layout with a gated yard and oversized overhead doors.

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    New Retail Space at Gallery Walk
    New Retail Space at Gallery Walk

    FM 802, Brownsville, TX 78526

    $2,107/Mo
    980 sqft 0.24 AC lot

    2024-built commercial space with C zoning and multiple stated retail and service use possibilities.

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    Flexible-Use Retail Space
    Flexible-Use Retail Space

    FM 802, Brownsville, TX 78526

    $1,957/Mo
    910 sqft 0.24 AC lot

    Built in 2024 and zoned C, the property supports office, medical, restaurant, spa, and clothing retail uses.

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    Retail Space in New Construction
    Retail Space in New Construction

    FM 802, Brownsville, TX 78526

    $1,957/Mo
    910 sqft 0.24 AC lot

    C-zoned commercial space supports office, medical, restaurant, spa, and retail uses.

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    Medical Office Condo with Pylon Sign
    Medical Office Condo with Pylon Sign

    632 N Ed Carey Dr., Harlingen, TX 78550

    $10,866/Mo
    2,833 sqft

    Multi-room layout includes sinks in most offices and can be adapted for medical or general office use.

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    Flexible Office Building
    Flexible Office Building

    2805 & 2809 S EXPRESSWAY 83, Harlingen, TX 78550

    Contact for pricing
    1.41 AC lot

    Multiple private offices, reception areas, and conference rooms support varied professional operations.

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    Office Suites Near Medical Centers
    Office Suites Near Medical Centers

    1514 S 77 SUNSHINE STRIP, Harlingen, TX 78550

    $1.00 SF/Yr
    1,000 sqft 10.98 AC lot

    Flexible configurations support medical, retail, sales, and office users.

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    Gallery Walk Retail Space
    Gallery Walk Retail Space

    000 Fm 802 D, Brownsville, TX 78526

    $1,956/Mo
    910 sqft

    Available space is suited to office, medical, restaurant, and retail applications.

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    Retail Space Near Medical Centers
    Retail Space Near Medical Centers

    1514 S 77 SUNSHINE STRIP, Harlingen, TX 78550

    $1.00 SF/Yr
    1,400 sqft 10.98 AC lot

    Multiple suite configurations are available for retail, office, medical, and sales operations.

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    Office Unit with Private Offices
    Office Unit with Private Offices

    1911 Lubbock St. Suite A, Harlingen, TX 78550

    Contact for pricing
    2,500 sqft

    Functional office layout near Valley Baptist Medical Center with dedicated storage, restrooms, and break room.

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    Professional Office Unit with Lobby
    Professional Office Unit with Lobby

    2489 W Business 77 Unit 2489, San Benito, TX 78586

    $2,400/Mo

    Configured with private offices, support rooms, and on-site parking.

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    Office and Medical Space
    Office and Medical Space

    1121 E Austin Ave, Harlingen, TX 78550

    Contact for pricing
    5,910 sqft 0.97 AC lot

    Ready-to-lease office/medical building offers 5,910 SF of adaptable space on an irregular 0.97-acre lot.

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    Office, Special Purpose
    Office, Special Purpose

    1911 Lubbock Street, Harlingen, TX 78550

    Contact for pricing
    2,500 sqft

    Medical Office Space · 2,500 SF

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    Medical Office Condo with Exam Rooms
    Medical Office Condo with Exam Rooms

    1713 Treasure Hills Blvd, Unit 2B, Harlingen, TX 78550

    Contact for pricing
    2,265 sqft

    Configured with six exam rooms, a doctor's office, reception area, and lab.

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    Four-Office Professional Suite
    Four-Office Professional Suite

    1610 E Harrison Ave. B, Harlingen, TX 78550

    $2,310/Mo
    1,459 sqft

    Flexible office layout with reception, employee lounge, and a private restroom.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    2014 Pease Street, Harlingen, TX 78550

    Contact for pricing

    Configured healthcare space with patient reception, clinical rooms, laboratory area, and dedicated parking.

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    Medical Office Space with Drive-Through
    Medical Office Space with Drive-Through

    707 W Sesame, Harlingen, TX 78550

    Contact for pricing

    Open-plan suite includes private office, conference area, and rear workroom within a former pharmacy setting.

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    Medical Office Suites with Exam Rooms
    Medical Office Suites with Exam Rooms

    200 W. First Street, La Feria, TX 78559

    Contact for pricing

    Configured for patient flow with reception, exam, clinical support, and staff areas.

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    Flexible Office Suite with Expressway Access
    Flexible Office Suite with Expressway Access

    2489 W Business 77, San Benito, TX 78586

    Contact for pricing

    Office space with flexible layout, excellent visibility, and convenient expressway access near Harlingen and San Benito.

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    Medical Office Space For Rent
    Medical Office Space For Rent

    18 Paseo Plaza, Brownsville, TX 78521

    Contact for pricing

    Healthcare office space in prime Brownsville trade area.

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    Class A Professional Office Building
    Class A Professional Office Building

    5700 N Expressway 77/83, Brownsville, TX 78526

    Contact for pricing

    Recently renovated office building near Expressway 77/83, Brownsville, TX.

    View details
    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 24 Active listings in Cameron County, TX, we suggest exploring alternatives.

    Cameron County, TX Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Cameron County, TX with 24 listings featured on our commercial real estate exchange. The current inventory includes 35,374 square feet of properties with an estimated lease value of $296.20.

    Estimated lease rates for Medical Office Space in Cameron County, TX begin at $10.37 SF/Yr, with an average of $24.68 SF/Yr and extend to $73.49 SF/Yr.
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    Featured Cameron County Real Estate Agencies

    Realmo connects you with licensed Cameron County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Keller Williams Lower Rio Grande Valley
    1713 E Tyler Ste A Harlingen, TX 78550
    Phone: 19564238877
    Harlingen Homes
    1201 E Harrison Ave Harlingen, TX 78550
    Phone: 19564235300
    www.harlingenhomes.com

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