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    Seneca, SC Office Spaces for Sale

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    Newry, SC West Union, SC Walhalla, SC
    Versatile Retail and Office Building
    Updated: Apr 17
    Versatile Retail and Office Building

    615 W N 1st Street, Seneca, SC 29678

    $214,900
    0.23 AC lot
    Commercial building in the City of Seneca with an open floor plan
    Includes 2 bathrooms and a side storage building
    Central air and electric heating with a new HVAC unit installed in April 2026
    Roof has shingle/composition materials
    Tenant occupied on a month‑to‑month basis
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    Commercial Building with Open Plan
    Updated: Apr 17
    Commercial Building with Open Plan

    615 W North 1st St, Seneca, SC 29678

    $214,900
    Tenant‑occupied commercial building in the City of Seneca with an open floor plan
    Includes two bathrooms and an additional storage building on the side
    New HVAC unit installed in April 2026
    Month‑to‑month tenant occupancy
    View details
    Office Building with Road Frontage
    Office Building with Road Frontage

    11081 N Radio Station Road, Seneca, SC 29678

    $217,000
    0.63 AC lot

    Single-building office asset just outside Seneca city limits with substantial road frontage on Radio Station Road.

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    Freestanding Office Building
    Freestanding Office Building

    631 By Pass 123, Seneca, SC 29678

    Contact for pricing

    For sale office building at 631 By Pass 123, offering a straightforward setup for professional tenants.

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    Land Near Clemson University
    Land Near Clemson University

    Union Station Dr, Seneca, SC 29678

    $350,000
    6.54 AC lot

    Land available near Clemson University, close to lakes.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 5 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 67 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Flex Space with Office and Warehouse
    Flex Space with Office and Warehouse

    450 N Hwy 11, West Union, SC 29696

    $1,100,000
    5.07 AC lot

    Move-in-ready flex facility with heated warehouse, private offices, and a drive-in door on high-visibility Hwy 11 frontage.

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    Flex Warehouse with Office Buildout
    Flex Warehouse with Office Buildout

    450 N Hwy 11, West Union, SC 29696

    $1,100,000
    5.07 AC lot

    Move-in-ready flex warehouse offers heated and cooled warehouse space plus office areas and drive-in access on Hwy 11.

    View details
    Free-Standing Office Building
    Free-Standing Office Building

    3691 Blue Ridge Boulevard, Walhalla, SC 29691

    $579,000
    0.77 AC lot

    Well-maintained office building with multiple rooms, two egress points, and ample front and rear parking for daily operations.

    View details
    Move-in Ready Office Space
    Move-in Ready Office Space

    111 N Earle St, Walhalla, SC 29691

    $349,900
    1,200 sqft · 0.35 AC lot

    Well-maintained office space suitable for various professional uses.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lot Near Wells Highway
    Commercial Lot Near Wells Highway

    Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678

    $395,000
    0.99 AC lot

    0.99-acre commercial lot with high visibility and easy access.

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    Highway Frontage Land Opportunity
    Highway Frontage Land Opportunity

    994 Us 123 Highway Unit 1.45 acr, Seneca, SC 29678

    $985,000
    1.45 AC lot

    1.45 acres with highway frontage, ideal for development.

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    Prime Commercial Land I-85 Frontage
    Prime Commercial Land I-85 Frontage

    105 Destination Boulevard, Anderson, SC 29621

    $949,000
    1.80 AC lot

    High-traffic commercial land with utilities ready for development near I-85.

    View details
    High-Traffic Commercial Land Available
    High-Traffic Commercial Land Available

    Destination Boulevard lot: R-1-A, Anderson, SC 29621

    $585,000
    1.45 AC lot

    1.45 acre commercial land with high visibility and accessibility.

    View details

    Off-Market Properties in Seneca, SC

    Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    8 Accountants Cir
    OFFICE BUILDING

    8 Accountants Cir, Seneca, SC 29678-2670

    Value Estimation by Request
    1,137 sqft · 0.15 AC lot
    View details
    203 Central Park Ln
    MEDICAL BUILDING

    203 Central Park Ln, Seneca, SC 29678-1156

    $520,000
    Estimated value
    4,578 sqft · 0.11 AC lot
    View details
    104 Wn 1st St
    OFFICE BUILDING

    104 Wn 1st St, Seneca, SC 29678-3248

    Value Estimation by Request
    5,400 sqft · 0.27 AC lot
    View details
    Seneca, SC 29678
    MEDICAL BUILDING

    Seneca, SC 29678

    Value Estimation by Request
    2,929 sqft · 0.27 AC lot
    View details
    693 Oak St
    MEDICAL BUILDING

    693 Oak St, Seneca, SC 29678-3827

    $535,000
    Estimated value
    4,900 sqft · 1.00 AC lot
    View details
    959 By Pass 123rd A Ste A
    MEDICAL BUILDING

    959 By Pass 123rd A Ste A, Seneca, SC 29678-4706

    $1,170,000
    Estimated value
    13,440 sqft · 1.52 AC lot
    View details
    108 Keowee School Rd
    OFFICE BUILDING

    108 Keowee School Rd, Seneca, SC 29672-6741

    Value Estimation by Request
    1,402 sqft · 0.78 AC lot
    View details
    Seneca, SC 29678
    OFFICE BUILDING

    Seneca, SC 29678

    Value Estimation by Request
    1,962 sqft · 0.60 AC lot
    View details
    735 Townville St
    OFFICE BUILDING

    735 Townville St, Seneca, SC 29678-2644

    Value Estimation by Request
    2,968 sqft · 0.55 AC lot
    View details
    528 By Pass 123rd G Ste G
    OFFICE BUILDING

    528 By Pass 123rd G Ste G, Seneca, SC 29678-0866

    Value Estimation by Request
    1,616 sqft · 0.05 AC lot
    View details
    2 Leas Courtyard Dr
    MEDICAL BUILDING

    2 Leas Courtyard Dr, Seneca, SC 29672-6660

    Value Estimation by Request
    3,320 sqft · 0.14 AC lot
    View details
    11 Professionals Cir
    DENTAL BUILDING

    11 Professionals Cir, Seneca, SC 29678-2669

    Value Estimation by Request
    2,848 sqft · 0.16 AC lot
    View details
    528 By Pass 123rd D Ste D
    OFFICE BUILDING

    528 By Pass 123rd D Ste D, Seneca, SC 29678-0866

    Value Estimation by Request
    2,282 sqft · 0.05 AC lot
    View details
    10626 Clemson Blvd
    MEDICAL BUILDING

    10626 Clemson Blvd, Seneca, SC 29678-4526

    $2,150,000
    Estimated value
    13,342 sqft · 0.25 AC lot
    View details
    15575 Wls Hwy
    MEDICAL BUILDING

    15575 Wls Hwy, Seneca, SC 29678-1664

    $905,000
    Estimated value
    9,944 sqft · 1.89 AC lot
    View details
    14 Professionals Cir
    OFFICE BUILDING

    14 Professionals Cir, Seneca, SC 29678-2669

    Value Estimation by Request
    2,830 sqft · 0.22 AC lot
    View details
    406 En 1st St
    OFFICE BUILDING

    406 En 1st St, Seneca, SC 29678-2742

    Value Estimation by Request
    1,300 sqft · 0.13 AC lot
    View details
    879 By Pass 123
    OFFICE BUILDING

    879 By Pass 123, Seneca, SC 29678-4755

    Value Estimation by Request
    1,440 sqft · 1.44 AC lot
    View details
    841 Wn 1st St
    OFFICE BUILDING

    841 Wn 1st St, Seneca, SC 29678-2528

    Value Estimation by Request
    1,100 sqft · 0.12 AC lot
    View details

    Seneca, SC Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Seneca, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $996,800.

    Sale prices for office spaces in Seneca, SC start at $0.00, averaging $199,360, and reaching up to $350,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 6
    Office buildings 2
    Medical Office Space 1

    Demographics Overview

    Population 36K
    Population Growth (5Y) +2.7%
    Median Household Income $62,735
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Seneca submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29678 $222.3K

    Listings Trend

    New vs delisted commercial listings in Oconee County

    New Delisted

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