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Seneca, SC

Commercial

Seneca, SC Commercial Land for Sale

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Newry, SC West Union, SC Walhalla, SC Westminster, SC Clemson, SC Townville, SC Salem, SC Central, SC

17 properties

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Two-Lot Live-Work Development Land

Updated: Jun 30

Two-Lot Live-Work Development Land

Tract 18/19 S Walnut Street, Seneca, SC 29678

$265,000

2.20 AC lot

Unique 2‑lot package on S. Walnut St: 1.49‑acre residential lot plus a .71‑acre tract next door.
Tract 18 is zoned residential; tract 19 is zoned commercial (buyer to confirm rezoning availability if desired).
Tract 18 utilities include power setup, water, and two septic systems (public remarks also reference “Tract 18 with 149 acres”—verify).
Owner will not separate the tracts—purchase includes both lots.
Location is less than 5 minutes from downtown Seneca’s retail/dining district and a short hop to Clemson University.

Graded Commercial Land

Updated: Oct 7, 2025

Graded Commercial Land

Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678

$395,000

0.99 AC lot

0.99‑acre commercial land parcel
Flat, graded terrain
Corner of Wells Hwy. & Return Church Rd. Highway
Less than two miles from Prisma Hospital
Ground lease and build‑to‑suit options available

Commercial Land Near Highway 123

Commercial Land Near Highway 123

1.8 Acres Rochester Highway, Seneca, SC 29672

$699,000

1.80 AC lot

Unrestricted 1.8-acre commercial land near major retailers and highways.

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Unrestricted Development Retail Site

Unrestricted Development Retail Site

8095 Keowee School Rd, Seneca, SC 29672

Contact for pricing

2,500 sqft 6.48 AC lot

Unrestricted commercial property with a 2,500 sq ft building, commercial kitchen, outbuildings, two ponds, and water/power access.

The Clemson Commercial Lot

The Clemson Commercial Lot

189 Seneca Creek Road, Seneca, SC 29678

$175,000

84,942 sqft 1.95 AC lot

1.95 Acres Land, The Clemson Commercial Lot

Commercial Development Land with Phase I

Commercial Development Land with Phase I

921 E North 1st St, Seneca, SC 29678

Contact for pricing

8.30 AC lot

Assemblage-completed commercial site with Phase 1 environmental completed and three rental properties currently under lease.

Prime Commercial Acreage For Sale

Prime Commercial Acreage For Sale

1018 E. North 1st Street, Seneca, SC 29678

$3,500,000

4.33 AC lot

4.3 acres in Seneca, SC, ideal for retail or hospitality.

Commercial

Commercial

Tract 18/19 S Walnut Street, Seneca, SC 29678

$265,000

Live-work space

Neighborhood Commercial Land Parcel

Neighborhood Commercial Land Parcel

701 E North 1st St, Seneca, SC 29678

Contact for pricing

1.40 AC lot

Level lot with two road frontages and Neighborhood Commercial zoning for retail, service, or professional uses.

Downtown Redevelopment Land Opportunity

Downtown Redevelopment Land Opportunity

725 E MAIN ST, Seneca, SC 29678

Contact for pricing

6.24 AC lot

Redevelopment land along E Main Street with historic textile mill character and flexible concept options.

Cleared Commercial Land Tract

Cleared Commercial Land Tract

1700 Blue Ridge Boulevard, Seneca, SC 29672

Contact for pricing

10.00 AC lot

Mostly cleared land with approximately 10 acres to be surveyed, located next to Parkway Products.

Unrestricted Commercial Land Near Highway

Unrestricted Commercial Land Near Highway

1.8 Acres Rochester Highway, Seneca, SC 29672

$699,000

1.80 AC lot

1.8 acres of unrestricted commercial land with high traffic count.

Commercial Land on Clemson Boulevard

Commercial Land on Clemson Boulevard

10149 & 10161 Clemson Blvd, Seneca, SC 29678

Contact for pricing

3.94 AC lot

3.94 acres of commercial land with road frontage.

Corner Lot in Seneca

Corner Lot in Seneca

911 E. North 1st Street Street, Seneca, SC 29678

$325,000

1.29 AC lot

1.29 acre corner lot zoned for commercial use.

Corner Development Land Acreage

Corner Development Land Acreage

183 / Keowee School Road, Seneca, SC 29672

$1,500,000

Unrestricted acreage with prominent corner frontage on Hwy 183 and Keowee School Road, plus city water available.

Land Near Clemson University

Land Near Clemson University

Union Station Dr, Seneca, SC 29678

Contact for pricing

6.54 AC lot

Land available near Clemson University, close to lakes.

Lake Keowee Acreage in Seneca

Lake Keowee Acreage in Seneca

45+/- Acres Knollwood Drive Unit Keowee I, Seneca, SC 29678

$2,250,000

45.00 AC lot

45+/- acres within Seneca city limits with utilities.

Based on your search, we've compiled Potential Opportunities for your consideration. Besides 17 Active Listings in Seneca, SC, we suggest to view alternatives - similar 55 Off-Market properties to explore as potential leads.

Off-Market Properties in Seneca, SC

Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

629 Business Park Dr

VACANT COMMERCIAL LAND

629 Business Park Dr, Seneca, SC 29678-1174

Value Estimation by Request

0.53 AC lot

501 En 1st St

VACANT COMMERCIAL LAND

501 En 1st St, Seneca, SC 29678-2869

Value Estimation by Request

1,247 sqft 0.22 AC lot

Seneca, SC 29678

VACANT COMMERCIAL LAND

Seneca, SC 29678

Value Estimation by Request

2.23 AC lot

Seneca, SC 29678

VACANT COMMERCIAL LAND

Seneca, SC 29678

Value Estimation by Request

17.55 AC lot

13040 Clemson Blvd

VACANT COMMERCIAL LAND

13040 Clemson Blvd, Seneca, SC 29678-1447

$3,590,000

Estimated value

1.88 AC lot

13014 Clemson Blvd

VACANT COMMERCIAL LAND

13014 Clemson Blvd, Seneca, SC 29678-1447

$2,790,000

Estimated value

0.89 AC lot

Seneca, SC 29672

VACANT COMMERCIAL LAND

Seneca, SC 29672

Value Estimation by Request

0.91 AC lot

Seneca, SC Commercial Land Market Trends and Statistics

Explore 72 commercial land for sale in Seneca, SC, showcased through 17 active listings on our real estate platform. These investment opportunities span a total of 4,454,446 square feet of properties for sale, with an estimated market value of $10,073,000.

Sale prices for commercial lots in Seneca, SC start at $175,000, averaging $1,007,300, and reaching up to $3,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 36K

Population Growth (5Y) +2.7%

Median Household Income $62,735

College Educated 31.9%

High-Yield Neighborhoods for Investment

Identify Seneca submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
29672	$699K
29678	$928.1K

Listings Trend

New vs delisted commercial listings in Oconee County

New Delisted

Total CRE Inventory on Market (SF)

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