Seneca, SC Commercial land for sale

Updated: Jul 10

Unrestricted Subdividable Land Parcel

12051 N Radio Station Road, Seneca, SC 29678

$799,900

22.18 AC lot

Unrestricted general use 22 +/- acres
Public water available
Currently taxed at agricultural rate
Subdividable
Located between Sandifer Blvd and Wells highway, about 5 minutes to downtown and Ram Cat Alley

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Updated: Jun 30

Two-Lot Live-Work Development Land

Tract 18/19 S Walnut Street, Seneca, SC 29678

$240,000

2.20 AC lot

Unique 2‑lot package on S. Walnut St: 1.49‑acre residential lot plus a .71‑acre tract next door.
Tract 18 is zoned residential; tract 19 is zoned commercial (buyer to confirm rezoning availability if desired).
Tract 18 utilities include power setup, water, and two septic systems (public remarks also reference “Tract 18 with 149 acres”—verify).
Owner will not separate the tracts—purchase includes both lots.
Location is less than 5 minutes from downtown Seneca’s retail/dining district and a short hop to Clemson University.

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Commercial Land with Existing Building

11081 N Radio Station Road, Seneca, SC 29678

$217,000

0.63 AC lot

Road-front commercial parcel with a 1973 structure, block construction, concrete flooring, and propane utility service.

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Commercial Land with House

215 Semper Fi Drive, Seneca, SC 29678

$900,000

12 sqft

The parcel includes a detached garage and a dwelling with an unfinished basement.

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Commercial Land with Highway Frontage

1.8 Acres Rochester Highway, Seneca, SC 29672

$699,000

1.80 AC lot

Unrestricted commercial land near Publix, Ingles, and DG, positioned by established highway routes.

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Commercial Land on Clemson Boulevard

10149 And 10161 Clemson Boulevard, Seneca, SC 29678

$1,200,000

3.94 AC lot

3.94 acres of commercial land with road frontage.

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Mixed-Use Property with Detached Workshop

10695 Clemson Boulevard, Seneca, SC 29678

$789,000

Unrestricted acreage combines residential space, storage improvements, utility access, and flexibility for business operations.

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Commercial Land with Existing Structure

298 By Pass 123, Seneca, SC 29678

$590,000

An existing commercial building and a surveyed tract front the Bypass 123 corridor in Seneca.

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Corner Commercial Land with Building

10732 Clemson Boulevard, Seneca, SC 29672

$550,000

Corner commercial land includes an existing brick building with open-shell interiors and access from Clemson Boulevard.

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Commercial Land Near Hospital Campus

1 Sheep Farm Rd, Seneca, SC 29672

$389,900

Commercial land with hospital adjacency, road access, and Control Free District zoning.

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The Clemson Commercial Lot

189 Seneca Creek Road, Seneca, SC 29678

$175,000

84,942 sqft 1.95 AC lot

1.95 Acres Land, The Clemson Commercial Lot

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Downtown Redevelopment Land Opportunity

725 E MAIN ST, Seneca, SC 29678

Contact for pricing

6.24 AC lot

Redevelopment land along E Main Street with historic textile mill character and flexible concept options.

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Level Commercial Land

523 E. North 1st Street, Seneca, SC 29678

$85,000

Level commercial land with shade trees and road frontage near downtown Seneca.

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Corner Lot in Seneca

911 E. North 1st Street Street, Seneca, SC 29678

$325,000

1.29 AC lot

1.29 acre corner lot zoned for commercial use.

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Land Near Clemson University

Union Station Dr, Seneca, SC 29678

Contact for pricing

6.54 AC lot

Land available near Clemson University, close to lakes.

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15 active listings match your search: Commercial Land for sale in Seneca, SC. Based on your search, we've also compiled 61 Potential Opportunities for your consideration: 4 properties in nearby cities and 57 off-market properties to explore as potential leads.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Cleared Commercial Development Site

00 Blue Ridge Boulevard, West Union, SC 29696

$160,696

Cleared and graded land with a stormwater retention pond and frontage on Development Drive.

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West Union Commercial Land Available

1210 W Main St, West Union, SC 29696

$65,000

1.29 AC lot

1.29 acres of commercial land with endless opportunities.

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Clemson Land for Development

76 Highway, Clemson, SC 29631

$1,299,774

7.66 AC lot

7+ acres of land near Clemson University.

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Commercial Land Development Parcel

W HWY 76, Clemson, SC 29631

$1,299,774

7.66 AC lot

Zoned Rm-1 and Rm-2, this Clemson property supports consideration of hotel or multifamily development.

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Off-Market Properties in Seneca, SC

Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.