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    Seneca, SC Office Buildings for Sale

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    Newry, SC West Union, SC Walhalla, SC Westminster, SC Clemson, SC Townville, SC Salem, SC Central, SC
    Office Building with Road Frontage
    Updated: Aug 21, 2024
    Office Building with Road Frontage

    11081 N Radio Station Road, Seneca, SC 29678

    $217,000
    0.63 AC lot
    Block construction building with concrete flooring, built in 1973
    Located just outside Seneca city limits on Radio Station Rd with busy road frontage
    Roof features shingle/composition materials
    Utilities: propane
    Original radio station building; towers shown behind the building are not on the property
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    Downtown Mixed-Use Commercial Building
    Updated: Aug 16, 2025
    Downtown Mixed-Use Commercial Building

    110 E North 1st St, Seneca, SC 29678

    $429,943
    5,000 sqft
    Two‑level commercial building with approx 5,000 SF total (2,500 SF per floor).
    Prominent street‑front storefront with high‑visibility frontage.
    Prime downtown Seneca address at 110 E N 1st Street, SC.
    Flexible layout suited for retail, office, dining, or mixed‑use concepts.
    Walkable to dining, shopping, and community events in downtown Seneca.
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    Freestanding Office Building
    Freestanding Office Building

    631 By Pass 123, Seneca, SC 29678

    Contact for pricing

    For sale office building at 631 By Pass 123, offering a straightforward setup for professional tenants.

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    Downtown Office Building
    Downtown Office Building

    950 West North 1st Street, Seneca, SC 29678

    Contact for pricing

    Office building with ample interior and exterior space and street visibility in downtown Seneca.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 4 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 68 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Anderson Office Building For Sale
    Anderson Office Building For Sale

    131 Straight Drive, Anderson, SC 29625

    $649,000
    4,550 sqft

    Well-located office building near Clemson Boulevard and AnMed Medical Center.

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    Three-Story Multi-Tenant Commercial Building
    Three-Story Multi-Tenant Commercial Building

    112 W Main Street, Walhalla, SC 29691

    $829,000
    0.96 AC lot

    Three-story building with multiple leased suites, including a large main-level event/restaurant space and a heated, cooled basement.

    View details
    Two-Building Office Property
    Two-Building Office Property

    4450 HIGHWAY 24, Anderson, SC 29626

    $420,000
    0.80 AC lot

    Two-office building portfolio in Anderson, SC offered with possible owner financing terms.

    View details
    Freestanding Office Building
    Freestanding Office Building

    3691 Blue Ridge Boulevard, Walhalla, SC 29691

    $579,000
    0.77 AC lot

    Free-standing office building on State Hwy 28 with 11 functional rooms, ample front and rear parking, and two points of egress.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lot Near Wells Highway
    Commercial Lot Near Wells Highway

    Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678

    $395,000
    0.99 AC lot

    0.99-acre commercial lot with high visibility and easy access.

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    Prime Commercial Land I-85 Frontage
    Prime Commercial Land I-85 Frontage

    105 Destination Boulevard, Anderson, SC 29621

    $949,000
    1.80 AC lot

    High-traffic commercial land with utilities ready for development near I-85.

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    High-Traffic Commercial Land Available
    High-Traffic Commercial Land Available

    Destination Boulevard lot: R-1-A, Anderson, SC 29621

    $585,000
    1.45 AC lot

    1.45 acre commercial land with high visibility and accessibility.

    View details
    High-Traffic Commercial Land Available
    High-Traffic Commercial Land Available

    Destination Boulevard lot: R-1-B + R-2, Anderson, SC 29621

    $585,000
    4.61 AC lot

    4.61 acres at I-85 and US 76-28 intersection.

    View details

    Off-Market Properties in Seneca, SC

    Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    8 Accountants Cir
    OFFICE BUILDING

    8 Accountants Cir, Seneca, SC 29678-2670

    Value Estimation by Request
    1,137 sqft 0.15 AC lot
    View details
    104 Wn 1st St
    OFFICE BUILDING

    104 Wn 1st St, Seneca, SC 29678-3248

    Value Estimation by Request
    5,400 sqft 0.27 AC lot
    View details
    108 Keowee School Rd
    OFFICE BUILDING

    108 Keowee School Rd, Seneca, SC 29672-6741

    Value Estimation by Request
    1,402 sqft 0.78 AC lot
    View details
    Seneca, SC 29678
    OFFICE BUILDING

    Seneca, SC 29678

    Value Estimation by Request
    1,962 sqft 0.60 AC lot
    View details
    735 Townville St
    OFFICE BUILDING

    735 Townville St, Seneca, SC 29678-2644

    Value Estimation by Request
    2,968 sqft 0.55 AC lot
    View details
    528 By Pass 123rd G Ste G
    OFFICE BUILDING

    528 By Pass 123rd G Ste G, Seneca, SC 29678-0866

    Value Estimation by Request
    1,616 sqft 0.05 AC lot
    View details
    528 By Pass 123rd D Ste D
    OFFICE BUILDING

    528 By Pass 123rd D Ste D, Seneca, SC 29678-0866

    Value Estimation by Request
    2,282 sqft 0.05 AC lot
    View details
    14 Professionals Cir
    OFFICE BUILDING

    14 Professionals Cir, Seneca, SC 29678-2669

    Value Estimation by Request
    2,830 sqft 0.22 AC lot
    View details
    406 En 1st St
    OFFICE BUILDING

    406 En 1st St, Seneca, SC 29678-2742

    Value Estimation by Request
    1,300 sqft 0.13 AC lot
    View details
    879 By Pass 123
    OFFICE BUILDING

    879 By Pass 123, Seneca, SC 29678-4755

    Value Estimation by Request
    1,440 sqft 1.44 AC lot
    View details
    841 Wn 1st St
    OFFICE BUILDING

    841 Wn 1st St, Seneca, SC 29678-2528

    Value Estimation by Request
    1,100 sqft 0.12 AC lot
    View details
    149 Thrift Ave
    OFFICE BUILDING

    149 Thrift Ave, Seneca, SC 29678-0915

    Value Estimation by Request
    1,700 sqft 2.60 AC lot
    View details
    1500 Oak St
    OFFICE BUILDING

    1500 Oak St, Seneca, SC 29678-1730

    Value Estimation by Request
    2,252 sqft 9.29 AC lot
    View details
    528 By Pass 123rd F Ste F
    OFFICE BUILDING

    528 By Pass 123rd F Ste F, Seneca, SC 29678-0866

    Value Estimation by Request
    1,514 sqft 0.04 AC lot
    View details
    Seneca, SC 29678
    OFFICE BUILDING

    Seneca, SC 29678

    Value Estimation by Request
    2,194 sqft 0.35 AC lot
    View details
    107 Wn 1st St Ste A
    OFFICE BUILDING

    107 Wn 1st St Ste A, Seneca, SC 29678-3268

    Value Estimation by Request
    1,584 sqft 0.12 AC lot
    View details
    1923 Blue Rdg Blvd
    OFFICE BUILDING

    1923 Blue Rdg Blvd, Seneca, SC 29672-6615

    Value Estimation by Request
    1,625 sqft 43.15 AC lot
    View details
    112 Oak St, Unit A-D
    OFFICE BUILDING

    112 Oak St, Seneca, SC 29678-3267

    Unit A-D
    $560,000
    Estimated value
    8,348 sqft 0.11 AC lot
    View details
    323 Main St
    OFFICE BUILDING

    323 Main St, Seneca, SC 29678-2743

    Value Estimation by Request
    3,900 sqft 0.11 AC lot
    View details
    211 Main St
    OFFICE BUILDING

    211 Main St, Seneca, SC 29678-3245

    Value Estimation by Request
    1,894 sqft 0.05 AC lot
    View details

    Seneca, SC Office Buildings Market Trends and Statistics

    Explore 72 office buildings for sale in Seneca, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 5,000 square feet of properties for sale, with an estimated market value of $646,943.

    Sale prices for office properties in Seneca, SC start at $217,000, averaging $323,471, and reaching up to $429,943 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office buildings 4
    Office Units 4
    Medical Office Space 2

    Demographics Overview

    Population 36K
    Population Growth (5Y) +2.7%
    Median Household Income $62,735
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Seneca submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29678 $217K

    Listings Trend

    New vs delisted commercial listings in Oconee County

    New Delisted

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