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    Seneca, SC
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    Seneca, SC Restaurants for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    Commercial Building in Seneca, SC
    $239,900
    0.23 Acres

    Commercial Building in Seneca, SC

    615 W N 1st Street, Seneca, SC 29678

    Commercial building with open floor plan suitable for various businesses.

    • Commercial building in Seneca with versatile potential for retail, office, restaurant, etc.
    • Open floor plan suitable for various business types.
    • Includes a storage building for added convenience.
    • Two bathrooms.
    • New HVAC unit installed in April 2026.
    Updated: Apr 17
    View details
    Turn-Key Restaurant Franchise Opportunity
    $1,900,000
    0.78 Acres

    Turn-Key Restaurant Franchise Opportunity

    1053 By Pass 123 Bypass, Seneca, SC 29678

    Turn-key national franchise restaurant with real estate for sale.

    • Turn‑key, cash‑flowing Moe's Southwest Grill franchise with associated real estate.
    • Built in 2020, substantially below replacement cost.
    • Located on the busiest highway in Seneca, SC with approximately 35,000 daily vehicles.
    • Limited fast casual restaurant competition in the direct market.
    • #1 for catering in the Upstate region (Greenville‑Spartanburg‑Anderson).
    Updated: Oct 10, 2025
    View details
    Prime Commercial Acreage For Sale
    $3,500,000
    4.33 Acres

    Prime Commercial Acreage For Sale

    4.3 acres in Seneca, SC, ideal for retail or hospitality.

    1018 E. North 1st Street, Seneca, SC 29678
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    Automotive Shop Near Lake Keowee
    $900,000

    Automotive Shop Near Lake Keowee

    10-bay automotive shop, redevelopment potential for fast food.

    445 By Pass 123, Seneca, SC 29678
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    Established Hibachi Restaurant for Sale
    $219,000

    Established Hibachi Restaurant for Sale

    Turnkey Hibachi restaurant with existing lease and equipment included.

    1510 Blue Ridge Boulevard, Seneca, SC 29672
    View details
    Based on your search, we've compiled 68 Potential Opportunities for your consideration. Besides 5 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 55 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Renovated Commercial Space on Main
    $490,000
    0.06 Acres

    Renovated Commercial Space on Main

    Prime commercial space ideal for retail, office, or restaurant.

    212 E Main Street, Walhalla, SC 29691
    View details
    Retail
    $490,000
    1,855 SF

    Retail

    Retail space · 1,855 SF

    212 E Main St, Walhalla, SC 29691
    View details
    Retail Opportunity with Road Frontage
    $375,000
    686 SF

    Retail Opportunity with Road Frontage

    Flat site suitable for retail, restaurant, or automotive businesses.

    821 W Main St, Central, SC
    View details
    Road Frontage Commercial Land
    $289,000
    686 SF

    Road Frontage Commercial Land

    Commercial land with road frontage, suitable for various businesses.

    821 West Main, Central, SC 29630
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Walhalla Commercial Corner Lot
    $229,900
    1.21 Acres

    Walhalla Commercial Corner Lot

    High-visibility corner lot suitable for various commercial ventures.

    Corner E South Broad and Earle Street, Walhalla, SC 29691
    View details
    Commercial Site in Liberty, SC
    $1,250,000
    5.80 Acres

    Commercial Site in Liberty, SC

    5.8 acre commercial site in a growing area.

    7227 Moorefeld Memorial Highway, Liberty, SC 29657
    View details
    High-Traffic Commercial Land Available
    $585,000
    1.45 Acres

    High-Traffic Commercial Land Available

    1.45 acre commercial land with high visibility and accessibility.

    Destination Boulevard lot: R-1-A, Anderson, SC 29621
    View details
    High-Traffic Commercial Land Available
    $585,000
    4.61 Acres

    High-Traffic Commercial Land Available

    4.61 acres at I-85 and US 76-28 intersection.

    Destination Boulevard lot: R-1-B + R-2, Anderson, SC 29621
    View details

    Off-Market Properties in Seneca, SC

    Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    122 Ram Cat Aly

    122 Ram Cat Aly

    RESTAURANT • 2,790 SF
    Value Estimation by Request
    122 Ram Cat Aly, Seneca, SC 29678-3244
    View details
    13020 Clemson Blvd

    13020 Clemson Blvd

    DRIVE-THRU RESTAURANT, FAST FOOD • 2,309 SF
    Value Estimation
    $2,345,000
    13020 Clemson Blvd, Seneca, SC 29678
    View details
    696 By Pass 123

    696 By Pass 123

    RESTAURANT • 4,933 SF
    Value Estimation by Request
    696 By Pass 123, Seneca, SC 29678-4750
    View details
    106 Nelson Ln

    106 Nelson Ln

    DRIVE-THRU RESTAURANT, FAST FOOD • 2,216 SF
    Value Estimation
    $670,000
    106 Nelson Ln, Seneca, SC 29678-1032
    View details
    515 By Pass 123

    515 By Pass 123

    RESTAURANT • 4,624 SF
    Value Estimation by Request
    515 By Pass 123, Seneca, SC 29678-0845
    View details
    407 Sheep Farm Rd

    407 Sheep Farm Rd

    RESTAURANT • 3,860 SF
    Value Estimation by Request
    407 Sheep Farm Rd, Seneca, SC 29672-9407
    View details
    1290 Doug Holw Rd

    1290 Doug Holw Rd

    RESTAURANT • 12,576 SF
    Value Estimation
    $2,945,000
    1290 Doug Holw Rd, Seneca, SC 29672-0703
    View details
    1528 Blue Rdg Blvd

    1528 Blue Rdg Blvd

    RESTAURANT • 2,977 SF
    Value Estimation by Request
    1528 Blue Rdg Blvd, Seneca, SC 29672-6601
    View details
    1003 By Pass 123

    1003 By Pass 123

    DRIVE-THRU RESTAURANT, FAST FOOD • 3,848 SF
    Value Estimation by Request
    1003 By Pass 123, Seneca, SC 29678-4762
    View details
    1610 Sandifer Blvd

    1610 Sandifer Blvd

    DRIVE-THRU RESTAURANT, FAST FOOD • 1,850 SF
    Value Estimation by Request
    1610 Sandifer Blvd, Seneca, SC 29678-0905
    View details
    305 By Pass 123

    305 By Pass 123

    RESTAURANT • 7,200 SF
    Value Estimation
    $1,170,000
    305 By Pass 123, Seneca, SC 29678-0819
    View details
    13500 Clemson Blvd

    13500 Clemson Blvd

    RESTAURANT • 1,669 SF
    Value Estimation
    $1,560,000
    13500 Clemson Blvd, Seneca, SC 29678-1457
    View details
    10906 Clemson Blvd

    10906 Clemson Blvd

    DRIVE-THRU RESTAURANT, FAST FOOD • 2,813 SF
    Value Estimation
    $3,005,000
    10906 Clemson Blvd, Seneca, SC 29678-1306
    View details
    1011 By Pass 123

    1011 By Pass 123

    DRIVE-THRU RESTAURANT, FAST FOOD • 3,725 SF
    Value Estimation
    $2,875,000
    1011 By Pass 123, Seneca, SC 29678-4762
    View details
    1053 By Pass 123

    1053 By Pass 123

    DRIVE-THRU RESTAURANT, FAST FOOD • 2,589 SF
    Value Estimation
    $555,000
    1053 By Pass 123, Seneca, SC 29678-4762
    View details
    119 Ram Cat Aly

    119 Ram Cat Aly

    RESTAURANT • 1,035 SF
    Value Estimation by Request
    119 Ram Cat Aly, Seneca, SC 29678-3243
    View details
    121 Ram Cat Aly

    121 Ram Cat Aly

    RESTAURANT • 2,070 SF
    Value Estimation by Request
    121 Ram Cat Aly, Seneca, SC 29678-3243
    View details
    109 Thrift Ave

    109 Thrift Ave

    DRIVE-THRU RESTAURANT, FAST FOOD • 1,750 SF
    Value Estimation
    $1,245,000
    109 Thrift Ave, Seneca, SC 29678-0915
    View details
    105 Woody Terry Rd

    105 Woody Terry Rd

    RESTAURANT • 1,224 SF
    Value Estimation by Request
    105 Woody Terry Rd, Seneca, SC 29678-5333
    View details

    Seneca, SC Restaurants Investment Opportunities Market Analysis

    Explore 60 restaurants for sale in Seneca, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $6,768,900.

    Sale prices for restaurant properties in Seneca, SC start at $219,000, averaging $1,353,780, and reaching up to $3,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Seneca, SC

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