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    Edwardsville, IL
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    Edwardsville, IL Office Spaces for Lease

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    Madison, IL Glen Carbon, IL Maryville, IL
    30 results
    Office Suite For Lease
    $500/Mo
    Office Suite For Lease

    340 S Fillmore Street, Edwardsville, IL 62025

    Single office suite for rent near downtown Edwardsville, Illinois.
    • All utilities included in monthly rent ($500/month).
    • Convenient location near downtown Edwardsville.
    • Access to MCT Bike Trail.
    • Ample parking available.
    • Shared kitchen and bath.
    Updated: Feb 25
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    Class A Office Space
    $2,300/Mo
    Class A Office Space

    3 Club Centre Suite A, Edwardsville, IL 62025

    Prime office space in Edwardsville, IL for lease.
    • Prime Class A office space in Club Centre location.
    • Located off State Route 157 with corner location.
    • Includes reception area, conference room, private offices, and open space.
    • Building equipped with elevator.
    • Shared kitchenette and handicapped accessible restrooms.
    Updated: Dec 10, 2025
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    Downtown Edwardsville Office Space
    $24 SF/Yr
    4,624 SF
    Downtown Edwardsville Office Space

    Prime office space adjacent to Madison County courthouse.

    241 N Main, Edwardsville, IL

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    Downtown Edwardsville Office/Retail Space
    $25 SF/Yr
    1,800 SF
    Downtown Edwardsville Office/Retail Space

    1,800 SF space with frontage and visibility on Main Street.

    220 N Main St, Edwardsville, IL

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    Downtown Edwardsville Retail/Office Space
    $25 SF/Yr
    1,029 SF
    Downtown Edwardsville Retail/Office Space

    Freestanding 1,029 SF retail/office space in downtown Edwardsville.

    501 N Main, Edwardsville, IL

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    Professional Office Space Available
    $1,350/Mo
    950 SF
    Professional Office Space Available

    950 SF professional office space for lease.

    9 Junction Dr, Edwardsville, IL

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    Downtown Edwardsville Office/Retail Space
    $22 SF/Yr
    1,000 SF
    Downtown Edwardsville Office/Retail Space

    Premier office/retail space in downtown Edwardsville at lighted intersection.

    100 N Main St, Edwardsville, IL 62025

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    Edwardsville Office Suites for Lease
    $25 SF/Yr
    7,266 SF
    Edwardsville Office Suites for Lease

    Office suites available in campus-like Mark Twain Plaza.

    103 W Vandalia St, Edwardsville, IL 62025

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    Edwardsville Office Building For Lease
    $3,500/Mo
    3,300 SF
    Edwardsville Office Building For Lease

    3,300 SF office building in downtown Edwardsville for lease.

    1310 N Main St, Edwardsville, IL 62025

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    Flexible Workspace Solutions Available Now
    Contact for pricing
    Flexible Workspace Solutions Available Now

    Global network of workspaces with tailored options for any business.

    101 W Vandalia St, Suite 125, Edwardsville, IL 62025

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    Edwardsville Mixed-Use Retail/Office Space
    $30 SF/Yr
    1,932 SF
    Edwardsville Mixed-Use Retail/Office Space

    New construction mixed-use building with retail, office, and restaurant spaces.

    400 N Main St, Edwardsville, IL 62025

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    Historic Office Space in Edwardsville
    $18 SF/Yr
    8,000 SF
    Historic Office Space in Edwardsville

    Unique creative office space in historic downtown Edwardsville, Illinois.

    201 Hillsboro Ave, Edwardsville, IL 62025

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    Downtown Edwardsville Office Space
    $25 SF/Yr
    2,520 SF
    Downtown Edwardsville Office Space

    2,520 SF office space for lease in downtown Edwardsville.

    228 N Main St, Edwardsville, IL 62025

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    Edwardsville Office Suites For Rent
    $25 SF/Yr
    4,462 SF
    Edwardsville Office Suites For Rent

    Office suites available in campus-like Mark Twain Plaza, Edwardsville, IL.

    101 W Vandalia St, Edwardsville, IL 62025

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    Downtown Edwardsville Office/Retail Space
    Contact for pricing
    Downtown Edwardsville Office/Retail Space

    Premier location with high visibility and traffic in downtown Edwardsville.

    100 N Main St, Edwardsville, IL 62025

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    Edwardsville Office Suites For Rent
    $25 SF/Yr
    1,531 SF
    Edwardsville Office Suites For Rent

    Office suites available in campus-like Mark Twain Plaza, Edwardsville.

    105 W Vandalia St, Edwardsville, IL 62025

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    Edwardsville Office Space For Rent
    $16 SF/Yr
    4,000 SF
    Edwardsville Office Space For Rent

    Office suite available in Sunset Hills Professional Center.

    1 Sunset Hills Professional Ctr, Edwardsville, IL 62025

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    Main Level Office Space Available
    $20 SF/Yr
    5,874 SF
    Main Level Office Space Available

    Professionally managed office space for lease, convenient location.

    1012 Plummer Dr, Edwardsville, IL 62025

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    Edwardsville Retail or Office Space
    Contact for pricing
    3,160 SF
    Edwardsville Retail or Office Space

    3,160 SF available in busy downtown Edwardsville corridor.

    120 N Main St, Edwardsville, IL 62025

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    Mark Twain Plaza Office Suites
    Contact for pricing
    7,266 SF
    Mark Twain Plaza Office Suites

    Office suites available for lease in Mark Twain Plaza.

    101 W Vandalia St, Edwardsville, IL 62025

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    Office Space Near Mannie Jackson Center
    Contact for pricing
    Office Space Near Mannie Jackson Center

    Office space for lease near downtown Edwardsville retail corridor.

    1310 N Main St, Edwardsville, IL 62025

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    New Mixed-Use Development in Edwardsville
    Contact for pricing
    New Mixed-Use Development in Edwardsville

    Class A building with retail, office, and restaurant spaces.

    400 N Main St, Edwardsville, IL 62025

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    Edwardsville Office/Retail Suites Available
    $25 SF/Yr
    2,720 SF
    Edwardsville Office/Retail Suites Available

    Class A office/retail suites available in mixed-use development.

    1001-1010 Enclave Blvd, Edwardsville, IL

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    Edwardsville, IL Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Edwardsville, IL with 30 listings featured on our commercial real estate exchange. The current inventory includes 51,008 square feet of properties with an estimated lease value of $336 /Mo.

    Estimated lease rates for Office Spaces in Edwardsville, IL begin at $12 SF/Yr, with an average of $22 SF/Yr and extend to $30 SF/Yr.
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