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Edwardsville, IL Office Spaces for Lease

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Glen Carbon, IL Maryville, IL South Roxana, IL Troy, IL Collinsville, IL Wood River, IL Granite City, IL Bethalto, IL
17 properties
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Class A Office Suite
Updated: Jun 23
Class A Office Suite

3 Club Centre Suite C, Edwardsville, IL 62025

$2,400/Mo
Class A office suite on the main floor
Reception area, conference room, private offices, and open‑plan workspace
In‑suite kitchenette
Shared handicapped accessible restrooms
Gross lease structure
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Professional Workspace Solutions at Il, Edwardsville - Vandalia St.. Contact us today to book a tour!
Updated: Jun 16
Professional Workspace Solutions at Il, Edwardsville - Vandalia St.. Contact us today to book a tour!

101 Vandalia St, Edwardsville, IL 62025

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2,037 sqft
Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
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Glass-Front Flex Space
Glass-Front Flex Space

2341 Plum St, Edwardsville, IL 62025

$1.00 SF/Yr
10,499 sqft

Flexible M-1 space combines offices, showroom, climate-controlled warehouse, and manufacturing areas for diverse commercial operations.

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Office Unit with Server Room
Office Unit with Server Room

3 Sunset Hills Executive Dr, Edwardsville, IL 62025

$1,800/Mo

Configured office space includes supplemental cooling, a large conference room, and a private bathroom.

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Professional Office Units with Private Offices
Professional Office Units with Private Offices

411 Edwardsville Rd, Edwardsville, IL 62294

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3,680 sqft

Efficient professional workspace includes private offices, meeting space, support rooms, and four restrooms.

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Office Units with Natural Light
Office Units with Natural Light

B-7251 Saint James Dr, Edwardsville, IL 62025

$800/Mo

Leasable offices include shared reception, parking, illuminated signage, and utilities included.

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Professional Office Building with Parking
Professional Office Building with Parking

224 S Main St, Edwardsville, IL 62025

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1,736 sqft

Professional office building with a functional layout, dedicated off-street parking, and convenient access in Edwardsville.

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Office Building With Signage
Office Building With Signage

1120 S State Rte 157, Edwardsville, IL 62025

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2,272 sqft

Office space offers monument and building signage with access to IL-157 and nearby I-270.

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Brick Office Building with Parking
Brick Office Building with Parking

10 Edwardsville Prof, Edwardsville, IL 62025

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840 sqft

Well-maintained brick office building in Edwardsville Professional Park with flexible floor plans and ample parking.

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Office Units with Signage Opportunity
Office Units with Signage Opportunity

2229 S State Route 157, Edwardsville, IL 62025

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New construction offers flexible buildout potential within Edwardsville’s office and medical corridor.

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Downtown Edwardsville Retail/Office Space
Downtown Edwardsville Retail/Office Space

501 N Main, Edwardsville, IL

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1,029 sqft 0.25 AC lot

Freestanding 1,029 SF retail/office space in downtown Edwardsville.

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Downtown Edwardsville Office/Retail Space
Downtown Edwardsville Office/Retail Space

220 N Main St, Edwardsville, IL

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1,800 sqft 0.06 AC lot

1,800 SF space with frontage and visibility on Main Street.

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Edwardsville Office Suites for Lease
Edwardsville Office Suites for Lease

103 W Vandalia St, Edwardsville, IL 62025

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7,266 sqft 2.08 AC lot

Office suites available in campus-like Mark Twain Plaza.

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Office Space Near Mannie Jackson Center
Office Space Near Mannie Jackson Center

1310 N Main St, Edwardsville, IL 62025

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3,300 sqft

Office space for lease near downtown Edwardsville retail corridor.

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Professional Office Space Available
Professional Office Space Available

1012 Plummer Dr, Edwardsville, IL 62025

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5,874 sqft

5,874 SF office space for lease, professionally managed.

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Downtown Edwardsville Office/Retail Space
Downtown Edwardsville Office/Retail Space

100 N Main St, Edwardsville, IL 62025

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2,550 sqft

Premier location with high visibility and traffic in downtown Edwardsville.

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Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 17 Active listings in Edwardsville, IL, we suggest exploring alternatives. Similar 8 Properties for Sales.

Similar Spaces for Sale in Edwardsville, IL

Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

Restaurant and Office Building
Restaurant and Office Building

140 N Main Street, Edwardsville, IL 62025

$1,025,000
5,720 sqft

Downtown Edwardsville building offers a bar and patio with office space on the second and third floors.

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Mixed-Use Building with Patio
Mixed-Use Building with Patio

140 N MAIN Street, Edwardsville, IL 62025

$1,025,000
0.10 AC lot

Brick commercial property with office space, a bar area, outdoor patio, and separate upper-level lounge space.

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Professional Office Building
Professional Office Building

224 South Main Street, Edwardsville, IL 62025

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1,736 sqft

Functional office layout with dedicated off-street parking at 224 S. Main Street.

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Two-Story Office Building
Two-Story Office Building

1 Horticultural, Edwardsville, IL 62025

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67,000 sqft

Includes a large cafe, grab-and-go market, executive suite, terrace seating, and abundant parking.

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Brick Office Building
Brick Office Building

100 N Research Drive, Edwardsville, IL 62025

$680,000

Currently in use with private offices, a conference room, kitchen area, and separate restrooms.

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Three-Story Office Building
Three-Story Office Building

240 S BUCHANAN ST, Edwardsville, IL 62025

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3,068 sqft

Three-story office building with ground-level kitchenette and a partially finished basement suited for office use.

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Commercial Land at Lighted Intersection
Commercial Land at Lighted Intersection

NE New Poag Road - Lot 6, Edwardsville, IL 62025

$554,083
1.59 AC lot

Flexible commercial land with public water and sewer, natural gas availability, and retail or upscale office use identified.

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Edwardsville, IL Office Spaces Lease Rates & Market Statistics

Explore 17 Office Spaces for lease in Edwardsville, IL on Realmo, a commercial real estate exchange covering the Edwardsville area. The current inventory totals 44,920 square feet of properties — an average of ~2,650 SF per listing.

Office Spaces lease rates in Edwardsville range from $7.39 SF/Yr at the entry level to $21 SF/Yr at the top of the market, averaging $14.19 SF/Yr. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $14.19 SF/Yr is 34% below the Illinois state average of $21.61 SF/Yr.

Edwardsville accounts for 24% of the 71 office spaces currently available across Madison County, where nearby markets include Alton and Granite City. By space type, the market includes 11 office units and 3 office buildings.

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