Medical Space

Alton, IL Medical Office Space for Lease

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Found 9 medical office space listings for lease in Alton, IL, averaging $14/SF/YR. Use lease type data to compare options faster.
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Third-Floor Office Unit
Updated: Jul 11
Third-Floor Office Unit

307 Henry St., Alton, IL 62002

$700/Mo
Approximately 560 SF of third‑floor office space
Previously configured for medical office use
Accessible elevator serves all four floors
Parking lot and on‑street parking available
Central air conditioning and forced‑air natural gas heat
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Elevator-Served Office Suite
Updated: Oct 20
Elevator-Served Office Suite

307 Henry St., Alton, IL 62002

$15 SF/Yr
Approximately 1,200 square feet on the building’s third floor
Elevator access serves all four floors
Full‑service lease includes taxes, utilities, insurance, CAM, and light janitorial services
North parking lot provides access to the suite
Building is in a HUBZone
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Elevator-Served Office Suite
Elevator-Served Office Suite

307 Henry St., Alton, IL 62002

Full service
$15 SF/Yr
1 space  800 sqft  4-story  Floor 3

Third-floor workspace in a full-service office building with elevator access and parking.

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Third-Floor Office Suite
Third-Floor Office Suite

317-307 Henry St, Alton, IL 62002

Full service
$15 SF/Yr
3–5 people  800 sqft  4-story  Floor 3

Full-service leasing includes utilities, building services, and elevator access.

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Medical Office Suite
Medical Office Suite

215 E Center Drive, Alton, IL 62002

Triple net (NNN)
$13 SF/Yr
2,799 sqft  Built 1998  0.54 acres
Highway access

Configured with reception, lab, private office, storage, kitchenette, and an accessible bathroom for immediate occupancy.

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Mixed-Use Office Suite
Mixed-Use Office Suite

215 E Center Drive #E & F, Alton, IL 62002

Triple net (NNN)
$13 SF/Yr
Multi-tenant  8,872 sqft  Built 1998
Highway access

The layout includes a reception area, private offices, lab space, a kitchenette, storage, and an accessible bathroom.

Reception area  Handicap bathroom  Office space  Lab Space
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Medical Office Building with Parking
Medical Office Building with Parking

1 Professional Dr, Alton, IL 62002

Contact for pricing
Multi-tenant  64,800 sqft  Built 1994  3-story
Highway access  C2

Two-story medical office building with a lower level, lobby, conference room, and ample off-street parking.

270 parking spaces
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Third-Floor Office Suite
Third-Floor Office Suite

307 Henry St. #302, Alton, IL 62002

Full service
$700/Mo
123–206 people  30,980 sqft  Built 1950  4-story

The building provides elevator service, north-lot access, and shared parking for office occupants.

Restaurant
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Third-Floor Office Suite
Third-Floor Office Suite

302-307 Henry St, Alton, IL 62002

Full service
$700/Mo
390–580 sqft  4-story

Professional office space with elevator access, north parking lot entry, and building services included.

Decaro's restaurant  Light janitorial services
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9 active listings match your search: Medical Office for lease in Alton, IL. Based on your search, we've also compiled 11 Potential Opportunities for your consideration: 4 spaces in nearby cities and 7 properties for sale.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Building
Medical Office Building

6944 N Hanley Road, Hazelwood, MO 63042

$5,000/Mo
3,303 sqft  Built 1975

A 3,303-square-foot building has a floor plan adapted for medical office use.

View details
Versatile Downtown Retail Office Space
Versatile Downtown Retail Office Space

15 S Florissant Rd, Saint Louis, MO 63135

$2,850/Mo

A ready-to-occupy suite with chandelier-lit main rooms and three offices plus storage for retail or professional uses.

View details
Medical Office Building
Medical Office Building

6944 N Hanley Road, Hazelwood, MO 63042

$5,000/Mo
3,303 sqft  Built 1975  2.28 acres

Former bank building adapted for medical office use with flexible interior spaces.

View details
Medical Office Building
Medical Office Building

9845 W Florissant Ave, Saint Louis, MO 63136

Triple net (NNN)
Contact for pricing
18–31 people  1 space  4,658 sqft
Road access

Office building offering prominent frontage, pylon signage, and ample surface parking with convenient ingress and egress.

View details

Similar Spaces for Sale in Alton, IL

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Medical Office Building
Medical Office Building

1 Professional Drive, Alton, IL 62002

$4,000,000
259–432 people  64,800 sqft  Built 1994  1 building  3-story  4.33 acres  brick & glass  Multi-tenant
Highway access  C2

Two-story commercial property with medical occupancy, shared amenities, elevators, and C2 General Commercial District zoning.

Elevator  270 spaces  Lobby  Bathrooms  Conference room
View details
Two-Space Office Building
Two-Space Office Building

3505 College Avenue, Alton, IL 62002

$649,500
2 units  3,600 sqft  Built 2000  1-story  0.57 acres  Multi-tenant
100% occupied  Highway access + Road access

Single-story professional property with occupied commercial spaces, substantial parking, and access from College Avenue.

Newer HVAC system
View details
Office Building with Detached Garage
Office Building with Detached Garage

2216 State Street, Alton, IL 62002

$225,000
0.39 acres

Brick office property with multiple workspaces and a detached garage.

View details
Office Building with Detached Garage
Office Building with Detached Garage

2216 State Street, Alton, IL 62002

$225,000

A split-entry layout offers two reception windows and multiple office areas for one business or several occupants.

View details
Medical Office Building with Parking
Medical Office Building with Parking

1 Professional Drive, Alton, IL 62002

$4,000,000
Built 1994

Three-level medical office property with shared building amenities, elevator service, and available first-floor space.

View details
Third-Floor Office Unit with Elevator
Third-Floor Office Unit with Elevator

307 Henry St., 317, Alton, IL 62002

Contact for pricing
3–5 people  800 sqft  1 building  4-story  Floor 3

The suite occupies the building’s third floor, with elevator service across all four levels.

Elevator
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Medical Office Suite
Medical Office Suite

307 Henry St., 311, Alton, IL 62002

Contact for pricing
1,200 sqft  1 building  4-story

A third-floor professional suite in an elevator-served building, with access from the north parking area.

View details

Alton, IL Medical Office Space Lease Rates & Market Statistics

Explore 9 Medical Office Space listings for lease in Alton, IL on Realmo, a commercial real estate exchange covering the Alton area. The current inventory totals 105,452 square feet of properties.

Medical Office Space lease rates in Alton range from $13 SF/Yr at the entry level to $15 SF/Yr at the top of the market, averaging $14.20 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $14.20 SF/Yr is 34% below the Illinois state average of $21.63 SF/Yr.

Alton accounts for 64% of the 14 medical office space listings currently available across Madison County, where nearby markets include Collinsville and Edwardsville. Medical Office Space listings make up 33% of the 27 Office Spaces currently for lease in Alton, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Office Units (23 listings) elsewhere in the Alton market.

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