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    Florence County, SC Office Buildings for Sale

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    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    1706 2Nd Loop Rd, Florence, SC 29501

    Office building with 7,517 square feet of space in Florence.

    • Handicap access: accessible approach with ramp.
    • Features office(s) and reception area.
    • Kitchen facility available.
    • Private restrooms.
    • Central heating and central air.
    Updated: Oct 24, 2025
    View details
    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    215 John St, Lake City, SC 29560

    Stand-alone office building with immediate occupancy in Lake City, SC.

    • Stand‑alone ±1722 SF building offers independence and privacy.
    • Immediate occupancy available.
    • Includes two large open rooms, two private offices, a breakroom, and two ADA restrooms.
    • Fenced parking area provides security and convenience.
    • ±.286 acre lot within Lake City limits.
    View details
    Downtown Florence Business Technology Center
    Contact for pricing
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.

    187 E Evans St, Florence, SC 29506
    View details
    Based on your search, we've compiled 491 Potential Opportunities for your consideration. Besides 3 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 486 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 2Nd Loop Rd, Florence, SC 29501
    View details
    Prime Commercial Development Site
    $980,000
    4.76 Acres

    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Dr, Florence, SC 29501
    View details

    Explore Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2601 Tv Rd

    2601 Tv Rd

    OFFICE BUILDING • 2,800 SF
    Value Estimation by Request
    2601 Tv Rd, Florence, SC 29501-0703
    View details
    255 Warley St

    255 Warley St

    OFFICE BUILDING • 3,590 SF
    Value Estimation by Request
    255 Warley St, Florence, SC 29501-4444
    View details
    531 Evans St

    531 Evans St

    OFFICE BUILDING • 1,948 SF
    Value Estimation by Request
    531 Evans St, Florence, SC 29501-3407
    View details
    1250 Celebration Blvd

    1250 Celebration Blvd

    OFFICE BUILDING • 1,524 SF
    Value Estimation by Request
    1250 Celebration Blvd, Florence, SC 29501-5498
    View details
    110 Trade St

    110 Trade St

    OFFICE BUILDING • 360 SF
    Value Estimation by Request
    110 Trade St, Pamplico, SC 29583
    View details
    140 Beulah Rd

    140 Beulah Rd

    OFFICE BUILDING • 2,011 SF
    Value Estimation by Request
    140 Beulah Rd, Lake City, SC 29560-7915
    View details
    117 12th Sauls St

    117 12th Sauls St

    OFFICE BUILDING • 1,978 SF
    Value Estimation by Request
    117 12th Sauls St, Lake City, SC 29560-2630
    View details
    119 Sauls St

    119 Sauls St

    OFFICE BUILDING • 1,827 SF
    Value Estimation by Request
    119 Sauls St, Lake City, SC 29560-2630
    View details
    831 Georgetown Hwy

    831 Georgetown Hwy

    OFFICE BUILDING • 432 SF
    Value Estimation by Request
    831 Georgetown Hwy, Johnsonville, SC 29555-8041
    View details
    316 Market St

    316 Market St

    OFFICE BUILDING • 336 SF
    Value Estimation by Request
    316 Market St, Timmonsville, SC 29161-1730
    View details
    312 Jones Rd

    312 Jones Rd

    OFFICE BUILDING • 42,745 SF
    Value Estimation
    $5,505,000
    312 Jones Rd, Olanta, SC 29114-9629
    View details
    Us Highway

    Us Highway

    OFFICE BUILDING • 1,652 SF
    Value Estimation by Request
    Us Highway, 52, SC
    View details
    Florence, SC 29505

    Florence, SC 29505

    OFFICE BUILDING • 1,130 SF
    Value Estimation by Request
    Florence, SC 29505
    View details
    Hwy 76th 301

    Hwy 76th 301

    OFFICE BUILDING • 2,128 SF
    Value Estimation by Request
    Hwy 76th 301, Florence, SC 29506
    View details
    Florence, SC 29501

    Florence, SC 29501

    OFFICE BUILDING • 22,400 SF
    Value Estimation
    $2,240,000
    Florence, SC 29501
    View details
    187 Evans St

    187 Evans St

    OFFICE BUILDING • 64,416 SF
    Value Estimation
    $4,345,000
    187 Evans St, Florence, SC 29506-2511
    View details
    780 Woody Jones Blvd

    780 Woody Jones Blvd

    OFFICE BUILDING • 7,860 SF
    Value Estimation
    $1,020,000
    780 Woody Jones Blvd, Florence, SC 29501-7433
    View details
    1835 Fairfield Cir

    1835 Fairfield Cir

    OFFICE BUILDING • 624 SF
    Value Estimation by Request
    1835 Fairfield Cir, Florence, SC 29501-6943
    View details
    2325 Irby St

    2325 Irby St

    OFFICE BUILDING • 2,442 SF
    Value Estimation by Request
    2325 Irby St, Florence, SC 29505-3426
    View details
    605 Irby St

    605 Irby St

    OFFICE BUILDING • 2,520 SF
    Value Estimation by Request
    605 Irby St, Florence, SC 29501-5211
    View details
    821 Lucas St

    821 Lucas St

    OFFICE BUILDING • 3,132 SF
    Value Estimation by Request
    821 Lucas St, Florence, SC 29501-1209
    View details

    Florence County, SC Office Buildings Investment Opportunities Market Analysis

    Explore 489 office buildings for sale in Florence County, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 13,927,352 square feet of properties for sale, with an estimated market value of $121,515,000.

    Sale prices for office properties in Florence County, SC start at $50,000, averaging $570,492, and reaching up to $15,640,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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