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    Greenville County, SC Medical Office Space for Lease

    22 results
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    Medical Office Space For Lease
    $26 SF/Yr
    45,200 SF

    Medical Office Space For Lease

    10 Enterprise Blvd., Greenville, SC 29615

    Medical office space near Prisma Health Patewood & Bon Secours.

    • Prime Location: One block from Prisma Health Patewood Campus & Bon Secours Francis Eastside.
    • Medical/Healthcare Focus: Ideal office space for medical or healthcare practices.
    • Flexible Lease Terms: Adaptable lease options to suit tenant needs.
    • Available Space: 1,634 - 3,297 SF available, offering options for different sized practices.
    • Renovated Common Areas: Updated and well‑maintained shared spaces.
    Updated: Jan 27
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    Medical Office Space For Lease
    $13 SF/Yr
    8,000 SF

    Medical Office Space For Lease

    3535 Pelham Road, Greenville, SC 29615

    Medical office space for lease in Greenville, South Carolina.

    • Prime location on Pelham Road corridor in Greenville County.
    • Convenient access: Less than a mile to I‑85.
    • Medical office space suitable for various practices.
    • Flexible space: Can be divided to suit tenant needs.
    • Features 9 private offices, 2 conference rooms, lobby, and break room.
    Updated: Sep 25, 2025
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    Greenville Medical Office Space
    $30 SF/Yr
    2,600 SF

    Greenville Medical Office Space

    Modern medical office space available for lease in Greenville, SC.

    3807 White Horse Rd, Greenville, SC
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    Medical Office Near Greenville Memorial
    $18 SF/Yr
    22,786 SF

    Medical Office Near Greenville Memorial

    Medical office space for rent near Greenville Memorial Hospital.

    8 Memorial Medical Ct, Greenville, SC
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    Retail Space in Growing Town
    Contact for pricing

    Retail Space in Growing Town

    Retail and QSR spaces available near Prisma Health Hospital.

    Fountain Inn, SC 29644
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    Medical Office Space For Lease
    $18 SF/Yr
    3,000 SF

    Medical Office Space For Lease

    Medical office space available for lease in Greenville, SC.

    274 B Commonwealth Drive, Greenville, SC 29615
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    Two-Story Office Building Available
    Contact for pricing
    5,500 SF

    Two-Story Office Building Available

    Two-story office building with ample parking and multiple access points.

    501 Roper Mountain Rd, Greenville, SC
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    Prime Medical Office Space
    $18 SF/Yr
    15,448 SF

    Prime Medical Office Space

    Eastside Greenville location near Prisma and Bon Secours campuses.

    800 Pelham Rd, Greenville, SC
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    Greenville Office/Medical Space For Rent
    Contact for pricing
    1,005 SF

    Greenville Office/Medical Space For Rent

    Office or medical space available in Greenville, SC.

    20 Creekview Ct, Greenville, SC
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    Medical Office Space For Rent
    Contact for pricing
    1,336 SF

    Medical Office Space For Rent

    Newly renovated medical office space in Greenville's medical corridor.

    62 Bear Dr, Greenville, SC
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    334,000 SF Office Building For Lease
    $19 SF/Yr

    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681
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    334,000 SF Office Building For Lease
    $19 SF/Yr

    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681
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    2,250 SF Office Building
    $12 SF/Yr

    2,250 SF Office Building

    2,250 SF Office Building

    105 Lydia St, Greenville, SC 29605
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    Retail/Medical Space in Travelers Rest
    Contact for pricing
    13,813 SF

    Retail/Medical Space in Travelers Rest

    High-visibility retail/medical space in a thriving Upstate community.

    6414 State Park Rd, Travelers Rest, SC 29690
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    Piedmont Office/Medical Suite For Rent
    $16 SF/Yr
    2,835 SF

    Piedmont Office/Medical Suite For Rent

    Office/medical suite for lease near Highway 85 and SC-153.

    103-107 Clair Dr, Piedmont, SC
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    Turn Key Medical Office Space
    $23 SF/Yr
    5,000 SF

    Turn Key Medical Office Space

    New construction medical office space in close proximity to airport.

    100 Constantine Wy, Greer, SC
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    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF

    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681
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    Greer Retail & Restaurant Space
    Contact for pricing
    2,400 SF

    Greer Retail & Restaurant Space

    Retail, restaurant, and medical office spaces available for lease.

    2000 Hwy 101 S, Greer, SC
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    Prime Greenville Location Retail/Medical
    Contact for pricing

    Prime Greenville Location Retail/Medical

    Retail or medical space in high-traffic Greenville location.

    75 E McBee Ave., Greenville, SC 29601
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    Greenville Office Space For Rent
    $23 SF/Yr
    5,600 SF

    Greenville Office Space For Rent

    Flexible office space near Patewood Medical Campus available for rent.

    127 Halton Village Cir, Greenville, SC
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    Land Available For Development
    Contact for pricing

    Land Available For Development

    Land available for ground lease or build to suit.

    13435 E Wade Hampton Blvd, Greer, SC 29651
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    Medical Office Space Near Hospital
    Contact for pricing
    4,232 SF

    Medical Office Space Near Hospital

    Stand-alone building ideal for medical use near Greenville Memorial.

    1200 W Faris Rd, Greenville, SC 29605
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    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 22 Active listings in Greenville County, SC, we suggest exploring alternatives. Similar 5 Properties for Sales.

    Explore Similar Spaces for Sale in Greenville County, SC

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Medical Office Building For Sale
    $2,395,000
    7,397 SF

    Medical Office Building For Sale

    Two-story, ±7,397 SF medical office building suited for owner-occupant.

    300 Regent Park Ct, Greenville, SC
    View details
    Mauldin Commercial Site For Sale
    $200,000
    1.00 Acre

    Mauldin Commercial Site For Sale

    1+ acre lot approved for medical offices in growing area.

    Corn and Miller Road, Mauldin, SC 29607
    View details

    Greenville County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Greenville County, SC with 22 listings featured on our commercial real estate exchange. The current inventory includes 1,444,841,640 square feet of properties with an estimated lease value of $94 SF/Yr.

    Estimated lease rates for Medical Office Space in Greenville County, SC begin at $18 SF/Yr, with an average of $23 SF/Yr and extend to $30 SF/Yr.
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