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San Antonio, TX Medical Office Space for Sale

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26 results
San Antonio Freestanding Commercial Building
$275,000
2,898 SF

San Antonio Freestanding Commercial Building

114 West Vestal Place, San Antonio, TX 78221

Versatile commercial building in San Antonio's Southside, ideal for customization.

  • High‑intensity C‑3 NA zoning allows for a wide range of high‑traffic commercial uses.
  • Freestanding ±2,898 SF building offers a versatile footprint.
  • Prime opportunity for a "value‑add" investor or business owner to customize the space.
  • Located in the heart of San Antonio’s Southside.
  • Existing professional office configuration includes reception/waiting area, multiple private offices, and a central hallway.
Updated: Mar 5
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Historic Office Building For Sale
$1,350,000
3,990 SF

Historic Office Building For Sale

118 E Ashby Pl, San Antonio, TX 78212

1915 property ideal for law firm or professional services.

  • Prime central location with convenient access to Downtown and major corridors.
  • Beautifully preserved 1915 property with timeless character.
  • Ideal for law firm, professional services, medical, or owner‑user.
  • Features a welcoming reception area with original fireplace, high ceilings, rich wood trim, and abundant natural light.
  • Includes impressive conference room, full kitchen, and multiple restrooms.
Updated: Feb 23
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Versatile Space in High-Traffic Location
Contact for pricing
2,630 SF

Versatile Space in High-Traffic Location

Adaptable office, retail, or medical space with customization options.

11800-1866 Wurzbach Rd, San Antonio, TX
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Medical Office Space Available
$409,000
1,825 SF

Medical Office Space Available

Prime medical center location with multiple offices and restrooms.

9386 Huebner Rd 108, San Antonio, TX 78240
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Medical/Physical Therapy Building For Sale
$699,000
6,012 SF

Medical/Physical Therapy Building For Sale

6,012 SF medical/physical therapy building with ample parking.

3326-3328 E Southcross Blvd, San Antonio, TX
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Medical Office Space in San Antonio
Contact for pricing
27,494 SF

Medical Office Space in San Antonio

Prime medical/office space in San Antonio's Medical Center area.

5107 Medical Dr, San Antonio, TX
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San Antonio Mixed-Use Property For Sale
$1,800,000
4,428 SF

San Antonio Mixed-Use Property For Sale

Mixed-use property with parking and development potential near stadium.

234 San Pedro, San Antonio, TX 78205
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Turnkey Surgery Center Condo
$895,000
4,200 SF

Turnkey Surgery Center Condo

Surgery center condo near San Antonio's medical corridor.

7272 Wurzbach Rd, San Antonio, TX 78240
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Medical Office Condo Investment
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Medical Office Condo Investment

Medical office condo near South Texas Medical Center.

4903 Golden Quail, San Antonio, TX 78240
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Medical Office Near Baptist Hospital
$880,000
2,340 SF

Medical Office Near Baptist Hospital

Medical office space for sale near Baptist Hospital.

530 Lexington, San Antonio, TX 78215
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Prime Office Space Available
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6,834 SF

Prime Office Space Available

Office space for rent in a premier location.

3602 Paesanos Pkwy, San Antonio, TX
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Medical Office Building in Medical Center
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12,012 SF

Medical Office Building in Medical Center

Two-story, 12,012 SF medical office building in San Antonio.

4775 Hamilton Wolfe Rd, San Antonio, TX
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Medical Office Near Stone Oak
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Medical Office Near Stone Oak

Medical office space for sale near Methodist Stone Oak Hospital.

116 Gallery Cir, San Antonio, TX 78258
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Medical Office Building For Sale
$4,950,000
37,708 SF

Medical Office Building For Sale

37,708 SF multi-tenant medical office building in San Antonio.

1123 N Main Ave, San Antonio, TX 78205
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Move-in Ready Office Space
$205,000
968 SF

Move-in Ready Office Space

968 SF office space with plumbing and ample parking.

7300 Blanco Rd, San Antonio, TX
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San Antonio Commercial Office Building
Contact for pricing
6,245 SF

San Antonio Commercial Office Building

6,245 sqft office building in Central San Antonio.

5415 Lost Ln, San Antonio, TX
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Retail Center Near Medical Center
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7,000 SF

Retail Center Near Medical Center

7,000 SF multi-tenant retail center near San Antonio Medical Center.

6423 Babcock Rd, San Antonio, TX
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Medical Imaging Center & Office
$2,065,313
6,022 SF

Medical Imaging Center & Office

Medical imaging center and office space for sale.

11923 Culebra Rd, San Antonio, TX 78253
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Medical Office Space For Sale
Contact for pricing
7,930 SF

Medical Office Space For Sale

Class A medical office space in a new office park.

5250 Rogers Rd, San Antonio, TX
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New Office Condo in San Antonio
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14,290 SF

New Office Condo in San Antonio

Class A office condo in a prime San Antonio location.

4318 DeZavala Rd, San Antonio, TX
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Medical Office Space For Sale
Contact for pricing

Medical Office Space For Sale

Second floor medical space off Stone Oak at 1604.

115 Gallery Cir 209, San Antonio, TX 78258
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San Pedro Avenue Investment Opportunity
$230,000

San Pedro Avenue Investment Opportunity

Renewed urban location, convenient access, and redevelopment potential.

234 San Pedro Avenue, San Antonio, TX 78205
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Westover Hills Area Medical Office
$4,799,958
9,853 SF

Westover Hills Area Medical Office

Medical office building in the Westover Hills area.

9139 Westover Hills Blvd, San Antonio, TX
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Class A Office-Condo Complex
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20,000 SF

Class A Office-Condo Complex

New Class A office condo complex in premier location.

4306-4318 De Zavala Rd, San Antonio, TX
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San Antonio, TX Medical Office Space Investment Opportunities Market Analysis

Explore 857 medical office space for sale in San Antonio, TX, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 86,596 square feet of properties for sale, with an estimated market value of $20,828,271.

Sale prices for medical spaces in San Antonio, TX start at $205,000, averaging $1,735,689, and reaching up to $4,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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