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    San Antonio, TX Medical Office Space for Lease

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    Balcones Heights, TX Castle Hills, TX Alamo Heights, TX
    80 results
    Serene Office Park Setting
    $16 SF/Yr
    3,275 SF

    Serene Office Park Setting

    14855 Blanco Road, San Antonio, TX 78216

    Office space in a well-located, highly visible office park.

    • Premier business environment in a serene office park setting.
    • Highly visible location at the Blanco and Bitters intersection.
    • Effortless access to 1604, 281, and Wurzbach Parkway.
    • Ample parking available.
    • Anchored by the well‑known Melting Pot Restaurant.
    Updated: Mar 25
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    Medical Office in Medical Center
    $33 SF/Yr
    10,449 SF

    Medical Office in Medical Center

    21 Spurs Lane, San Antonio, TX 78240

    Four-story medical office building in San Antonio's Medical Center.

    • Located in the South Texas Medical Center, providing close access to Med Center hospitals
    • In‑house surgery center and STRIC (South Texas Radiology Imaging Center)
    • Garage parking available
    • Diverse tenant mix offering referral opportunities
    • On‑site convenience store
    Updated: Nov 22, 2025
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    Renovated Office Space in Oak Hills
    $25 SF/Yr
    4,540 SF

    Renovated Office Space in Oak Hills

    Medical/Office space for lease, convenient location, undergoing renovation.

    1735 Babcock Rd, San Antonio, TX
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    Medical Office on Broadway Street
    $28 SF/Yr
    2,515 SF

    Medical Office on Broadway Street

    Second-generation medical office space available for lease.

    8005 Broadway St, San Antonio, TX
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    Medical office complex with flexible floor plans and ample parking.

    5364 Fredericksburg Rd, San Antonio, TX 78229
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    Medical Office Space Available
    Contact for pricing
    1,958 SF

    Medical Office Space Available

    Class A medical office building near restaurants and retailers.

    7719 Interstate 35 S, San Antonio, TX 78224
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    Stone Oak Medical Office Space
    Contact for pricing
    1,701 SF

    Stone Oak Medical Office Space

    Second-generation medical office space in the Stone Oak market.

    155 E Sonterra Blvd, San Antonio, TX 78258
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    Medical Office Space Available
    Contact for pricing
    3,741 SF

    Medical Office Space Available

    Class A medical office building near restaurants and retailers.

    4103 N Loop 1604 W, San Antonio, TX 78249
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    Medical Office Space Available
    Contact for pricing
    610 SF

    Medical Office Space Available

    Class A medical office building near hospital and university.

    8230 N Loop 1604 W, San Antonio, TX 78249
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    Turnkey Medical/Retail Space Available
    Contact for pricing
    17,047 SF

    Turnkey Medical/Retail Space Available

    Turnkey medical and second-generation retail space for lease.

    6801 SAN PEDRO AVENUE, San Antonio, TX 78216
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    Turnkey Medical Space Available
    $24 SF/Yr
    1,720 SF

    Turnkey Medical Space Available

    Second-generation medical space in a vibrant trade area.

    2327 Sw Military Dr, San Antonio, TX
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    Accessible Medical/Office Space Near Downtown
    Contact for pricing
    2,065 SF

    Accessible Medical/Office Space Near Downtown

    Ground-level access, gated courtyard, near Downtown and the Pearl.

    2632 Broadway, San Antonio, TX 78215
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    Medical Office Space For Rent
    Contact for pricing
    64,644 SF

    Medical Office Space For Rent

    Medical office space available in redeveloped Sunset Road corridor.

    San Antonio, TX 78209
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    Medical/Office Space Available
    Contact for pricing
    554 SF

    Medical/Office Space Available

    554 SF medical/office space for rent.

    7940 Floyd Curl Dr, San Antonio, TX 78229
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    San Antonio Medical/Office Space
    Contact for pricing
    1,823 SF

    San Antonio Medical/Office Space

    1823 SF medical/office space available for lease.

    225 E Sonterra Blvd, San Antonio, TX 78258
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    Medical Office Sublease Opportunity
    Contact for pricing
    4,000 SF

    Medical Office Sublease Opportunity

    Medical office space available for sublease near Somerset Rd.

    San Antonio, TX 78211
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    Medical/Office Space Near Methodist Hospital
    $18 SF/Yr

    Medical/Office Space Near Methodist Hospital

    Medical/office space available near Methodist Stone Oak Hospital.

    116 Gallery Cir, San Antonio, TX 78258
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    Medical Office Complex For Rent
    Contact for pricing

    Medical Office Complex For Rent

    Seven-building medical office complex with flexible floor plans.

    5360 Fredericksburg Rd, San Antonio, TX 78229
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    Dominion Drive Office Space Available
    $30 SF/Yr
    1,489 SF

    Dominion Drive Office Space Available

    Professionally designed office space near The Dominion Country Club.

    4 Dominion Drive, San Antonio, TX
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    Medical Office Space For Lease
    Contact for pricing

    Medical Office Space For Lease

    First-floor medical office space with Loop 1604 visibility.

    4515 N Loop 1604 W, San Antonio, TX 78249
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    Medical Office Building with Balconies
    Contact for pricing
    13,963 SF

    Medical Office Building with Balconies

    Four-story medical office building in San Antonio's Medical Center.

    5441 Babcock Road, San Antonio, TX 78240
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    Medical Office Sublease Opportunity
    $21 SF/Yr
    7,646 SF

    Medical Office Sublease Opportunity

    Sublease opportunity: 7,646 SF fully built-out medical space.

    700 E Sonterra Blvd, San Antonio, TX
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    Medical Office in Stone Oak
    $31 SF/Yr
    2,325 SF

    Medical Office in Stone Oak

    Medical office space available in a growing San Antonio area.

    19114 US-281, San Antonio, TX 78221
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    Medical Office Building with Parking
    $2,271/Mo
    1,262 SF

    Medical Office Building with Parking

    Renovated medical office space with 24-hour access, controlled entry, and ample on-site parking for patients and staff.

    401-2040 Babcock Rd, San Antonio, TX 78201
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    San Antonio, TX Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in San Antonio, TX with 80 listings featured on our commercial real estate exchange. The current inventory includes 117,513 square feet of properties with an estimated lease value of $457 /Mo.

    Estimated lease rates for Medical Office Space in San Antonio, TX begin at $16 SF/Yr, with an average of $22 SF/Yr and extend to $36 SF/Yr.
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    Browse Medical Office Space for Lease Near San Antonio, TX

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    Most Searched ZIP Codes in San Antonio, TX

    • 78258
    • 78240
    • 78229
    • 78249
    • 78215
    • 78216
    • 78231
    • 78209
    • 78211
    • 78221
    • 78224

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