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    San Antonio, TX Medical Office Space for Lease

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    Houston, TX Dallas, TX Austin, TX
    82 results
    Serene Office Park Setting
    $16 SF/Yr
    3,275 SF

    Serene Office Park Setting

    14855 Blanco Road, San Antonio, TX 78216

    Office space in a well-located, highly visible office park.

    • Premier business environment in a serene office park setting.
    • Highly visible location at the Blanco and Bitters intersection.
    • Effortless access to 1604, 281, and Wurzbach Parkway.
    • Ample parking available.
    • Anchored by the well‑known Melting Pot Restaurant.
    Updated: Mar 25
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    Renovated Office Space in Oak Hills
    $25 SF/Yr
    4,540 SF

    Renovated Office Space in Oak Hills

    1735 Babcock Rd, San Antonio, TX

    Medical/Office space for lease, convenient location, undergoing renovation.

    • Convenient access to Loop 410 and IH 10, close proximity to San Antonio International Airport and Medical Center.
    • Option to lease entire second floor or subdivide to 1,780 SF.
    • Building currently undergoing renovation with new HVAC and elevator.
    • Fantastic opportunity for medical/office lease in Oak Hills neighborhood.
    • NNN Lease Term.
    Updated: Nov 25, 2025
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    Medical Office on Broadway Street
    $28 SF/Yr
    2,515 SF

    Medical Office on Broadway Street

    Second-generation medical office space available for lease.

    8005 Broadway St, San Antonio, TX
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    Medical/Office Space Near Methodist Hospital
    $18 SF/Yr

    Medical/Office Space Near Methodist Hospital

    Medical/office space available near Methodist Stone Oak Hospital.

    116 Gallery Cir, San Antonio, TX 78258
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    Medical Office Complex For Rent
    Contact for pricing

    Medical Office Complex For Rent

    Seven-building medical office complex with flexible floor plans.

    5360 Fredericksburg Rd, San Antonio, TX 78229
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    Medical office complex with flexible floor plans and ample parking.

    5364 Fredericksburg Rd, San Antonio, TX 78229
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    Stone Oak Medical Office Space
    Contact for pricing
    1,701 SF

    Stone Oak Medical Office Space

    Second-generation medical office space in the Stone Oak market.

    155 E Sonterra Blvd, San Antonio, TX 78258
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    Medical Office Space Available
    $18 SF/Yr
    12,014 SF

    Medical Office Space Available

    Office space for rent near Methodist Stone Oak Hospital.

    116 Gallery Cir, San Antonio, TX 78258
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    Medical Office Space Available
    Contact for pricing
    3,741 SF

    Medical Office Space Available

    Class A medical office building near restaurants and retailers.

    4103 N Loop 1604 W, San Antonio, TX 78249
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    Medical Office Space Available
    Contact for pricing
    1,958 SF

    Medical Office Space Available

    Class A medical office building near restaurants and retailers.

    7719 Interstate 35 S, San Antonio, TX 78224
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    Medical Office Space Available
    Contact for pricing
    610 SF

    Medical Office Space Available

    Class A medical office building near hospital and university.

    8230 N Loop 1604 W, San Antonio, TX 78249
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    Turnkey Medical/Retail Space Available
    Contact for pricing
    17,047 SF

    Turnkey Medical/Retail Space Available

    Turnkey medical and second-generation retail space for lease.

    6801 SAN PEDRO AVENUE, San Antonio, TX 78216
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    Medical Office Space For Lease
    Contact for pricing

    Medical Office Space For Lease

    First-floor medical office space with Loop 1604 visibility.

    4515 N Loop 1604 W, San Antonio, TX 78249
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    Medical/Office Space Available
    Contact for pricing
    554 SF

    Medical/Office Space Available

    554 SF medical/office space for rent.

    7940 Floyd Curl Dr, San Antonio, TX 78229
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    San Antonio Medical/Office Space
    Contact for pricing
    1,823 SF

    San Antonio Medical/Office Space

    1823 SF medical/office space available for lease.

    225 E Sonterra Blvd, San Antonio, TX 78258
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    Medical Office Space Available
    $16 SF/Yr
    12,342 SF

    Medical Office Space Available

    Move-in ready medical office space in San Antonio.

    6623 S Zarzamora St, San Antonio, TX
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    Turnkey Medical Space Available
    $24 SF/Yr
    1,720 SF

    Turnkey Medical Space Available

    Second-generation medical space in a vibrant trade area.

    2327 Sw Military Dr, San Antonio, TX
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    Stone Oak Medical Office Space
    Contact for pricing
    6,267 SF

    Stone Oak Medical Office Space

    9,790 SF medical office in Stone Oak area.

    19223 Stonehue, San Antonio, TX 78258
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    Medical Office Sublease Opportunity
    $21 SF/Yr
    7,646 SF

    Medical Office Sublease Opportunity

    Sublease opportunity: 7,646 SF fully built-out medical space.

    700 E Sonterra Blvd, San Antonio, TX
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    Modernized Medical Office Building
    Contact for pricing
    25,000 SF

    Modernized Medical Office Building

    Extensively renovated medical office building with ambulatory surgical center.

    1804 NE Loop 410, San Antonio, TX
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    Dominion Drive Office Space Available
    $30 SF/Yr
    1,489 SF

    Dominion Drive Office Space Available

    Professionally designed office space near The Dominion Country Club.

    4 Dominion Drive, San Antonio, TX
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    Alamo Heights Medical Office Space
    Contact for pricing
    2,627 SF

    Alamo Heights Medical Office Space

    Class A medical office space for lease in San Antonio.

    3338 Oakwell Ct, San Antonio, TX
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    Medical/Office Space Near I-10
    $30 SF/Yr
    27,675 SF

    Medical/Office Space Near I-10

    27,675 SF medical/office space undergoing renovation, completion mid-2025.

    9100 McDermott Fwy, San Antonio, TX
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    Medical Office Space Available
    Contact for pricing
    115,918 SF

    Medical Office Space Available

    Medical office space for rent on hospital campus.

    1139 E Sonterra Blvd, San Antonio, TX
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    San Antonio, TX Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in San Antonio, TX with 82 listings featured on our commercial real estate exchange. The current inventory includes 2,747,764,800 square feet of properties with an estimated lease value of $175 SF/Yr.

    Estimated lease rates for Medical Office Space in San Antonio, TX begin at $16 SF/Yr, with an average of $21 SF/Yr and extend to $28 SF/Yr.
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    Browse Medical Office Space for Lease Near San Antonio, TX

    Popular Searches in San Antonio, TX

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    Most Searched ZIP Codes in San Antonio, TX

    • 78258
    • 78229
    • 78231
    • 78240
    • 78251
    • 78253
    • 78215
    • 78216
    • 78217
    • 78221
    • 78232

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