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Madison County, IL Healthcare Properties for Sale

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Charming Cottage for Commercial Use
$150,000
714 SF

Charming Cottage for Commercial Use

509 Pearl Street, Godfrey, IL 62035

Updated cottage suitable for retail or office with parking.

  • Large paved and fenced parking area with space for approximately 8‑10 vehicles.
  • Flexible opportunity for various business types with a special use permit.
  • Updated for commercial use while retaining the charm of a cozy cottage.
  • Capped plumbing in place from previous hair salon, a bonus for related businesses.
  • Most recently operated as a pet spa.
Updated: Mar 4
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Maryville Healthcare Facility For Sale
$1,200,000
26,408 SF

Maryville Healthcare Facility For Sale

152 Wilma Drive, Maryville, IL 62062

26,408 SF healthcare property on 2.94 acres in Maryville.

  • Prior usage as a Nursing Home facility.
  • Excellent location.
  • Ideal for future usage as an Assisted Living / Memory Care / Adult Day Care facility.
  • Great visibility.
  • Includes a wide range of appliances such as Cooktop, Dishwasher, Dryer, Freezer, Refrigerator, and Washer.
Updated: Nov 21, 2025
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East Alton Commercial Building Sale
$60,000
2,100 SF

East Alton Commercial Building Sale

Commercial building suitable for various businesses in centralized location.

25 S 9th Street, East Alton, IL 62024
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Alton Medical Campus Opportunity
Contact for pricing
221,754 SF

Alton Medical Campus Opportunity

Vacant medical campus in historic Alton, Illinois.

915 E 5th St, Alton, IL
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Based on your search, we've compiled 73 Potential Opportunities for your consideration. Besides 4 Active listings in Madison County, IL, we suggest exploring several alternatives: similar 65 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Development Land with I-255 Visibility
$475,675
12.00 Acres

Development Land with I-255 Visibility

12 acres of development ground with frontage and visibility.

Sumner Ln, Wood River, IL
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Vaughn Road Land Opportunity
$1,500,729
5.22 Acres

Vaughn Road Land Opportunity

5.22 acres of land fronting Vaughn Road/111.

0 S Bellwood Dr, Wood River, IL
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Commercial Land in Wood River
$44,900

Commercial Land in Wood River

Potential building site with high traffic and corner location.

1300 E Edwardsville Road, Wood River, IL 62095
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Roxana Land Parcel For Sale
$1,432,000
35.80 Acres

Roxana Land Parcel For Sale

35.8 acres in Roxana with utilities on site.

Hedge Rd, East Alton, IL
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Explore Off-Market Properties in Madison County, IL

Consider similar Off-Market properties in Madison County, IL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

395 Edwardsville Rd

395 Edwardsville Rd

HOMES (RETIRED, NURSING) • 80,033 SF
Value Estimation
$2,215,000
395 Edwardsville Rd, Wood River, IL 62095-1600
View details
220 Fld Xing Dr

220 Fld Xing Dr

HOMES (RETIRED, NURSING) • 51,190 SF
Value Estimation
$1,010,000
220 Fld Xing Dr, Highland, IL 62249-3882
View details
308 4th St

308 4th St

HOMES (RETIRED, NURSING) • 1,995 SF
Value Estimation by Request
308 4th St, Alton, IL 62002-6107
View details
4400 Industrial Dr

4400 Industrial Dr

HOMES (RETIRED, NURSING) • 2.54 Acres
Value Estimation by Request
4400 Industrial Dr, Alton, IL 62002-5938
View details
2101 State St

2101 State St

HOMES (RETIRED, NURSING) • 0.23 Acres
Value Estimation by Request
2101 State St, Granite City, IL 62040-4726
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3941 Humbert Rd

3941 Humbert Rd

HOMES (RETIRED, NURSING) • 0.42 Acres
Value Estimation by Request
3941 Humbert Rd, Alton, IL 62002-7112
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6415 Humbert Rd

6415 Humbert Rd

HOMES (RETIRED, NURSING) • 5.19 Acres
Value Estimation by Request
6415 Humbert Rd, Godfrey, IL 62035-2224
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400 Main St

400 Main St

HOMES (RETIRED, NURSING) • 16,952 SF
Value Estimation by Request
400 Main St, Wood River, IL 62095-1426
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1425 6th St

1425 6th St

HOMES (RETIRED, NURSING) • 8,012 SF
Value Estimation by Request
1425 6th St, Madison, IL 62060-1417
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6960 State Rte 162

6960 State Rte 162

HOMES (RETIRED, NURSING) • 63,147 SF
Value Estimation
$1,015,000
6960 State Rte 162, Maryville, IL 62062-8522
View details
515 Niagara St

515 Niagara St

HOMES (RETIRED, NURSING) • 7,888 SF
Value Estimation by Request
515 Niagara St, East Alton, IL 62024-1087
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2302 State St

2302 State St

HOMES (RETIRED, NURSING) • 2,819 SF
Value Estimation by Request
2302 State St, Alton, IL 62002-4379
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1902 Brown St

1902 Brown St

HOMES (RETIRED, NURSING) • 10,110 SF
Value Estimation by Request
1902 Brown St, Alton, IL 62002-3972
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1900 Brown St

1900 Brown St

HOMES (RETIRED, NURSING) • 3,928 SF
Value Estimation by Request
1900 Brown St, Alton, IL 62002-3978
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Pershing Ave

Pershing Ave

HOMES (RETIRED, NURSING) • 1,718 SF
Value Estimation by Request
Pershing Ave, Wood River, IL 62095
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808 Swsw Pl

808 Swsw Pl

HOMES (RETIRED, NURSING) • 4,740 SF
Value Estimation by Request
808 Swsw Pl, Edwardsville, IL 62025-3661
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4029 Aberdeen Ave

4029 Aberdeen Ave

HOMES (RETIRED, NURSING) • 1,788 SF
Value Estimation by Request
4029 Aberdeen Ave, Alton, IL 62002-3127
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213 Pr St

213 Pr St

HOMES (RETIRED, NURSING) • 4,756 SF
Value Estimation by Request
213 Pr St, Bethalto, IL 62010-1306
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1608 Eastport Plaza Dr

1608 Eastport Plaza Dr

Office Units • 20,000 SF
Value Estimation by Request
1608 Eastport Plaza Dr, Collinsville, IL 62234
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1336 Mercantile Dr

1336 Mercantile Dr

Medical Office Space • 25,000 SF
Value Estimation by Request
1336 Mercantile Dr, Highland, IL 62249
View details

Madison County, IL Healthcare Properties Investment Opportunities Market Analysis

Explore 69 healthcare properties for sale in Madison County, IL, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 5,879,382 square feet of properties for sale, with an estimated market value of $20,210,000.

Sale prices for medical real estate in Madison County, IL start at $85,000, averaging $412,448, and reaching up to $1,895,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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