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    South San Francisco, CA Commercial Real Estate for Sale

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    26 properties
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    Mixed-Use Facility with Laboratory Space
    Updated: Apr 23
    Mixed-Use Facility with Laboratory Space

    South San Francisco, CA 94080

    $41,000,000
    21,552 sqft 3.65 AC lot
    21,552‑square‑foot facility on 3.648 acres
    2019 construction with approximately 9,500 SF of office, 4,500 SF of laboratory, and 7,000 SF of warehouse and inspection space
    Federal government tenant under a 13‑year triple‑net lease
    Four interior dock‑high doors sized for 53‑foot tractor‑trailers
    62 assigned parking spaces
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    Industrial Warehouse with Loading Docks
    Updated: Dec 5, 2024
    Industrial Warehouse with Loading Docks

    253 E Harris Ave, South San Francisco, CA 94080

    $6,500,000
    19,800 sqft 0.46 AC lot
    19,800‑square‑foot industrial warehouse on 0.46 acres
    Two warehouse condominiums with two APNs
    Two loading docks, one grade‑level door, and 12 parking spaces
    19‑foot ceilings with fire sprinklers and two ADA‑compliant restrooms
    2,000‑amp main panel at 480/277 volts
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    Renovated Flex Space with Loading Dock
    Renovated Flex Space with Loading Dock

    20-338 N Canal St, South San Francisco, CA 94080

    $1,490,000
    1,968 sqft

    Renovated warehouse-office unit with a kitchenette, two restrooms, storage, and separate customer and loading access.

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    Mixed-Use Property in Downtown South
    Mixed-Use Property in Downtown South

    20 South Linden Avenue, South San Francisco, CA 94080

    $1,500,000
    3,455 sqft 7.65 AC lot

    Mixed-use property in a thriving downtown location with high visibility.

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    NNN Government Operations Facility
    NNN Government Operations Facility

    560 Eccles Avenue, South San Francisco, CA 94080

    $41,000,000
    21,552 sqft 3.65 AC lot

    Purpose-built facility combines office, laboratory, warehouse, and inspection space under a Triple Net lease.

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    Retail Storefront Below Condos
    Retail Storefront Below Condos

    889 McLellan Drive, South San Francisco, CA 94080

    Contact for pricing
    1,293 sqft

    Retail units are available in multiple sizes within a storefront level directly beneath newly constructed luxury residences.

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    Auto Shop with Leased Yard
    Auto Shop with Leased Yard

    201 Cypress Ave, South San Francisco, CA 94080

    Contact for pricing
    2,750 sqft 0.23 AC lot

    Automotive property combining an auto body shop structure with a separately leased taxi-use yard.

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    Industrial Condo with Roll-Up Door
    Industrial Condo with Roll-Up Door

    South San Francisco, CA 94080

    Contact for pricing
    7,200 sqft

    Industrial condominium featuring high-ceiling office space, commercial kitchen, cooler/freezer, and a dry storage warehouse.

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    Industrial Building with In-Place Lease
    Industrial Building with In-Place Lease

    323 Canal Street, South San Francisco, CA 94080

    Contact for pricing
    11,000 sqft

    Leased industrial property in South San Francisco with an existing five-year lease term.

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    South San Francisco Flex Space
    South San Francisco Flex Space

    Airport Boulevard, South San Francisco, CA 94080

    $1,350,000
    3,930 sqft 0.11 AC lot

    3,930 SF flex space on 5,081 SF parcel.

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    Industrial Warehouse Building
    Industrial Warehouse Building

    275 South Maple Avenue, South San Francisco, CA 94080

    Contact for pricing
    70,000 sqft

    Large warehouse property positioned near Amazon, Costco, and FedEx facilities.

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    Combined Flex Space Units
    Combined Flex Space Units

    451 Victory AVE 5, South San Francisco, CA 94080

    $499,000
    2,208 sqft

    Combined flex space units with office and warehouse areas.

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    Mixed-Use Property with Restaurant
    Mixed-Use Property with Restaurant

    231 Lux Avenue, South San Francisco, CA 94080

    $1,298,000
    1,584 sqft

    Mixed-use property with a long-standing restaurant and residential unit.

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    T5L-Zoned Industrial Property
    T5L-Zoned Industrial Property

    141 S Maple Ave, South San Francisco, CA 94080

    Contact for pricing
    73,616 sqft

    Industrial property in South San Francisco with access to U.S. Highway 101, I-280, and San Francisco International Airport.

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    Functional Industrial Building For Sale
    Functional Industrial Building For Sale

    1139 Airport Boulevard, South San Francisco, CA 94080

    $1,350,000
    3,930 sqft

    3,930 SF industrial building with flexible space and warehouse.

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    Warehouse Office with Loading Dock
    Warehouse Office with Loading Dock

    338 N Canal Street # 20, South San Francisco, CA 94080

    $1,490,000

    Renovated unit includes a front office, kitchenette, storage, and separate loading access.

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    Downtown South San Francisco Investment
    Downtown South San Francisco Investment

    20-24 Linden Avenue #20, South San Francisco, CA 94080

    $1,799,000
    2,760 sqft 0.18 AC lot

    Customizable space in a thriving downtown location.

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    Leased Warehouse with Dock-High Doors
    Leased Warehouse with Dock-High Doors

    South San Francisco, CA 94080

    Contact for pricing
    211,259 sqft

    Single-tenant warehouse leased to FedEx with 45 dock-high doors and 18 to 26 clear heights.

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    Industrial Space Available For Lease
    Industrial Space Available For Lease

    171 Beacon Street, South San Francisco, CA 94080

    Contact for pricing
    8,500 sqft

    Industrial property featuring 8,500 square feet available for lease.

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    Vacant Apartment Assemblage
    Vacant Apartment Assemblage

    100 Hickey Blvd, South San Francisco, CA 94080

    Contact for pricing
    0.93 AC lot

    Two parcels are offered vacant with T3C zoning and access to BART within half a mile.

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    Retail Space Below Condos
    Retail Space Below Condos

    889 McLellan Dr, South San Francisco, CA 94080

    Contact for pricing
    1,139 sqft

    Retail suites are available in multiple sizes, located directly below newly constructed luxury residential condos.

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    T5C-Zoned Commercial Parcel
    T5C-Zoned Commercial Parcel

    1015-1057 El Camino Real, South San Francisco, CA 94080

    Contact for pricing
    197,762 sqft

    Located at 1015-1057 El Camino Real in South San Francisco.

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    Flex Warehouse Office Suite
    Flex Warehouse Office Suite

    5-451 Victory Ave, South San Francisco, CA 94080

    $499,000

    Combined units 4 and 5 offer warehouse space with ADA restrooms, office buildout, and second-floor access to a storage mezzanine.

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    Two-Bedroom Triplex
    Two-Bedroom Triplex

    South San Francisco, CA 94080

    $1,355,000

    Residential property with public utilities, wall-furnace heating, and tar/gravel roofing.

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    South San Francisco, CA Commercial Real Estate Market Trends and Statistics

    Explore 72 commercial real estate for sale in South San Francisco, CA, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 667,258 square feet of properties for sale, with an estimated market value of $101,130,000.

    Sale prices for business properties in South San Francisco, CA start at $499,000, averaging $7,779,230, and reaching up to $41,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    South San Francisco, CA CRE market trends — vacancy, lease rates and price per SF, updated monthly
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    Demographics Overview

    Population 65K
    Population Growth (5Y) -3.8%
    Median Household Income $135,966
    College Educated 26.3%

    High-Yield Neighborhoods for Investment

    Identify South San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    94080 $9M

    Taxes & Financing

    Tax Rate (average for all types) 1.16%
    Property Tax per SF $7.35 per SF
    Tax Rate vs County Average 0.02 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in San Mateo County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in San Mateo County

    Retail

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in South San Francisco fall within the 50,000 to 100,000 square foot range.

    How Realmo verifies these figures

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