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    South San Francisco, CA Commercial Real Estate for Lease

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    Cost-Efficient Office Space at CA, South San Francisco - Spaces Oyster Point. Contact us today to book a tour!
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    Warehouse Facility with Loading Docks
    Updated: Jan 24, 2025
    Warehouse Facility with Loading Docks

    253 E Harris Ave, South San Francisco, CA 94080

    $33,000/Mo
    19,800 sqft 0.46 AC lot
    19,800 square feet of warehouse space across two warehouse condominiums
    Two loading docks plus an on‑grade level door
    19‑foot ceiling height and 12 parking spaces
    4,000‑amp main panel at 480/227 volts
    Mixed‑use industrial zoning with fire sprinklers and two ADA‑compliant restrooms
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    Retail Space with Floor Drains
    Updated: Aug 20
    Retail Space with Floor Drains

    324-328 Grand Ave, South San Francisco, CA 94080

    $3,650/Mo
    3,650 sqft
    Two retail units with available configurations from 500 to 3,150 SF
    3,650 SF property with separately metered spaces
    Floor drains installed in the retail units
    Refrigeration may be available
    One covered parking spot may be available
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    South San Francisco Industrial Space
    South San Francisco Industrial Space

    930 Linden Avenue, South San Francisco, CA 94080

    $19,700/Mo
    9,975 sqft

    Industrial space for lease in South San Francisco, California.

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    Biotech Lab and Office Suite
    Biotech Lab and Office Suite

    1 Tower Pl, South San Francisco, CA 94080

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    14,674 sqft

    Flex suite configured as a biology lab and tissue culture space with office areas and multiple conference rooms.

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    Two-Story Flex Space with Elevator
    Two-Story Flex Space with Elevator

    453-467 Forbes Boulevard, South San Francisco, CA 94080

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    3,786 sqft

    Two-story flex space with monitored security, elevator, and prewired CAT-6 throughout.

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    Laboratory Office Building
    Laboratory Office Building

    285 E Grand Ave, South San Francisco, CA 94080

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    65,764 sqft

    Fully integrated biology, tissue culture, chemistry, and vivarium lab space with large suite and floor configurations.

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    Warehouse Space in Two Configurations
    Warehouse Space in Two Configurations

    361 Swift Ave, South San Francisco, CA 94080

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    10,758 sqft

    Industrial warehouse availability offers two separate space options in South San Francisco.

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    Distribution Center with HVAC Office
    Distribution Center with HVAC Office

    275 South Maple Avenue, South San Francisco, CA 94080

    Contact for pricing
    70,000 sqft

    Sprinklered distribution facility with dedicated offices, conference space, and warehouse racking.

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    Office Space Walking Distance to Caltrain
    Office Space Walking Distance to Caltrain

    South San Francisco, CA 94080

    Contact for pricing
    5,283 sqft

    Office space in the South San Francisco life science cluster with convenient Highway 101 access and walkable CalTrain access.

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    Corner Flex Warehouse with Lab Potential
    Corner Flex Warehouse with Lab Potential

    436 N Canal St, Unit 10, South San Francisco, CA 94080

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    3,710 sqft

    Corner flex/warehouse condo with 1,000 sf office, central HVAC, 400-amp power, and 9 reserved spaces.

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    Move-In Ready Office Lab Suite
    Move-In Ready Office Lab Suite

    600 Gateway Blvd, South San Francisco, CA 94080

    Contact for pricing
    4,889 sqft

    Plug-and-play office lab suite with access to autoclave; lab equipment is negotiable.

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    Centrally Located Office Building
    Centrally Located Office Building

    South San Francisco, CA 94080

    Contact for pricing
    9,655 sqft

    Office building in the South San Francisco life science cluster with walking access to CalTrain and nearby Highway 101 access.

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    Corner Office Suite with Meeting Rooms
    Corner Office Suite with Meeting Rooms

    1486 Huntington Ave, South San Francisco, CA 94080

    Contact for pricing
    2,621 sqft

    Third-floor corner office suite featuring three private offices and three meeting rooms, with elevator access and 8 parking spaces.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    601 Gateway Blvd, South San Francisco, CA 94080

    Contact for pricing
    10,451 sqft

    Centrally located office space in the South San Francisco life science cluster near CalTrain and Highway 101 access.

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    Office Space Near CalTrain
    Office Space Near CalTrain

    South San Francisco, CA 94080

    Contact for pricing
    14,168 sqft

    Office space in the South San Francisco Life Science cluster with walking access to CalTrain and convenient Highway 101 access.

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    Warehouse with Repair Yard
    Warehouse with Repair Yard

    935 Linden Avenue, South San Francisco, CA 94080

    Contact for pricing
    3,300 sqft

    Warehouse space with an approved auto and bus repair use, plus a separate outdoor yard component.

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    Two-Story Flex Warehouse with Elevator
    Two-Story Flex Warehouse with Elevator

    453-467 Forbes Boulevard, South San Francisco, CA 94080

    Contact for pricing
    3,244 sqft

    Two-story flex building includes an elevator, renovated office areas, and a high-clear warehouse with monitored security.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    601 Gateway Blvd, South San Francisco, CA 94080

    Contact for pricing
    5,557 sqft

    Centrally located office space in the South San Francisco life science cluster, with CalTrain within walking distance.

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    Two-Story Warehouse with Office Buildout
    Two-Story Warehouse with Office Buildout

    453-467 Forbes Boulevard, South San Francisco, CA 94080

    Contact for pricing
    4,915 sqft

    Two-story warehouse facility features a renovated lobby, elevator service, and high-clear-height warehousing space.

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    Office Units Near Life Science Cluster
    Office Units Near Life Science Cluster

    South San Francisco, CA 94080

    Contact for pricing
    10,208 sqft

    Office units with access to restaurants, retail, fitness centers, hotels, marina amenities, public transportation, and nearby residential communities.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    South San Francisco, CA 94080

    Contact for pricing
    7,107 sqft

    Centrally located office option within the South San Francisco life science cluster, walkable to CalTrain.

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    Insulated Flex Warehouse with Offices
    Insulated Flex Warehouse with Offices

    140 Beacon St, South San Francisco, CA 94080

    Contact for pricing
    24,000 sqft

    Insulated, fully sprinklered warehouse with office space, skylights, and multiple grade-level doors for flexible operations.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    601 Gateway Blvd, South San Francisco, CA 94080

    Contact for pricing
    2,801 sqft

    Office space in the South San Francisco life science cluster with CalTrain access and nearby retail, dining, and hotels.

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    Flex Space with High Clear Height
    Flex Space with High Clear Height

    453-467 Forbes Boulevard, South San Francisco, CA 94080

    Contact for pricing
    4,300 sqft

    Two-story flex building with an elevator, renovated lobby and common areas, and prewired CAT-6 for connectivity.

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    South San Francisco, CA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in South San Francisco, CA with 141 listings featured on our commercial real estate exchange. The current inventory includes 3,630,409 square feet of properties with an estimated lease value of $124.27.

    Estimated lease rates for Commercial real estate in South San Francisco, CA begin at $7.25 SF/Yr, with an average of $24.85 SF/Yr and extend to $43.92 SF/Yr.
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