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South San Francisco, CA Commercial Real Estate for Lease

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115 results
CA, South San Francisco - Spaces Oyster Point
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Corner Office Space Available
$2 SF/Yr
2,621 SF

Corner Office Space Available

1486 Huntington Avenue, South San Francisco, CA 94080

Prominent corner office space near transportation and shopping.

  • Excellent Location: Just off Hwy 380 and El Camino Real
  • Walking distance (0.5 miles) to San Bruno BART and Tanforan Shopping Center
  • Adjacent to new Safeway development at Discovery Station
  • Prominent corner office on the 3rd floor
  • 3 Private Offices
Updated: Mar 25
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South San Francisco Office/Lab Sublease
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22,365 SF

South San Francisco Office/Lab Sublease

651 Gateway Boulevard, South San Francisco, CA 94080

Full floor office/lab space available for sublease through July 2029.

  • Full floor (± 22,365 RSF) divisible office/lab space available for sublease through July 2029.
  • Prominent location on Highway 101 corridor with easy access.
  • Free shuttle service to San Francisco Airport (10 minutes away).
  • Full‑building lab conversion with new laboratory infrastructure and robust MEP systems.
  • Brand new Class A exteriors, lobby, and lab warm shell core.
Updated: Jan 27
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Office/Warehouse Suite For Rent
$1.75 SF/Yr
5,180 SF

Office/Warehouse Suite For Rent

Office/warehouse suite featuring dock-high loading and ample parking.

South San Francisco, CA
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Prime Retail Space in California
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Prime Retail Space in California

Exceptional retail leasing opportunity in a vibrant South San Francisco location.

200 Airport Boulevard, South San Francisco, CA 94080
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South San Francisco Industrial Building
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29,800 SF

South San Francisco Industrial Building

Freestanding industrial building with office/lab space for rent.

250 Hillside Boulevard, South San Francisco, CA 94080
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Functional Lab/Office Space Available
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8,711 SF

Functional Lab/Office Space Available

Prime location, functional lab/office space near transportation.

600 Gateway Blvd, South San Francisco, CA 94080
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South San Francisco Warehouse Space
$2 SF/Yr
6,000 SF

South San Francisco Warehouse Space

6,000 SF office warehouse with secure yard near Hwy 101.

150 West Harris Avenue, South San Francisco, CA 94080
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Oyster Point Flex/Lab Space
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10,248 SF

Oyster Point Flex/Lab Space

30,140 SF flex/lab space available for lease.

333 Oyster Point Blvd, South San Francisco, CA 94080
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Class A Lab & Office
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34,988 SF

Class A Lab & Office

Sublease opportunity: 34,988 SF of Class A lab & office.

131 Oyster Point Blvd, South San Francisco, CA 94080
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South San Francisco Flex Space
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30,491 SF

South San Francisco Flex Space

Flex space available for rent in South San Francisco.

400 E Jamie Ct, South San Francisco, CA 94080
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Retail Space on Airport Boulevard
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1,977 SF

Retail Space on Airport Boulevard

Retail space available for lease in South San Francisco.

200 Airport Blvd, South San Francisco, CA 94080
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South San Francisco Industrial Space
$19,700/Mo
9,975 SF

South San Francisco Industrial Space

Industrial space for lease in South San Francisco, California.

930 Linden Avenue, South San Francisco, CA 94080
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South San Francisco Industrial Building
$2 SF/Yr
36,881 SF

South San Francisco Industrial Building

36,881 SF industrial building with freight access and prime location.

200 Shaw Road, South San Francisco, CA 94080
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South San Francisco Commercial Space
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South San Francisco Commercial Space

Commercial space available for rent in South San Francisco.

578 Eccles Avenue, South San Francisco, CA 94080
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South San Francisco Warehouse Space
$18 SF/Yr
12,104 SF

South San Francisco Warehouse Space

Industrial warehouse space with office, grade-level doors, and parking.

255-263 Utah Ave, South San Francisco, CA
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South San Francisco Warehouse Space
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124,000 SF

South San Francisco Warehouse Space

Warehouse space with highway visibility near downtown and life science.

720 Dubuque Avenue, South San Francisco, CA 94080
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Life Science Campus for Rent
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300,000 SF

Life Science Campus for Rent

Vibrant campus with amenities near Biotech Bay Area corridor.

180 El Camino Real, South San Francisco, CA 94080
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South San Francisco Office Space
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14,000 SF

South San Francisco Office Space

14,000 sqft office space available for rent.

1487 Huntington Ave, South San Francisco, CA 94080
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South San Francisco Flex Space
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16,421 SF

South San Francisco Flex Space

Flex space with labs, vivarium, and convenient transit access.

225 Gateway Blvd, South San Francisco, CA
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South San Francisco Office Space
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40,606 SF

South San Francisco Office Space

Office building with 40,606 square feet available for rent.

453-467 Forbes Blvd, South San Francisco, CA 94080
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Oyster Point Ferry Station Access
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Oyster Point Ferry Station Access

Convenient access to transportation options and shuttle services.

700 Gateway Blvd, South San Francisco, CA 94080
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South San Francisco Office Space
$2.00 SF/Yr
29,470 SF

South San Francisco Office Space

LEED Gold certified office space with excellent transportation access.

701 Gateway Blvd, South San Francisco, CA
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South San Francisco Warehouse Space
$2 SF/Yr
9,764 SF

South San Francisco Warehouse Space

Warehouse space for rent, convenient location near Highway 101.

138 West Harris Avenue, South San Francisco, CA 94080
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South San Francisco, CA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in South San Francisco, CA with 115 listings featured on our commercial real estate exchange. The current inventory includes 151,310,495,160 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Commercial real estate in South San Francisco, CA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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