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    South San Francisco, CA Flex Space for Sale

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    San Bruno, CA Brisbane, CA Colma, CA
    6 listings
    Fully Secured High-Tech Biotech Facility
    $48,000,000
    3.65 Acres
    Fully Secured High-Tech Biotech Facility

    560 Eccles AVE, South San Francisco, CA 94080

    2019-built facility with mission-critical labs, dedicated power backup, and secure dock access for large tractor-trailers.
    • Premier 21,552 SF high‑tech biotech facility built in 2019 on a 3.65‑acre site
    • Interior includes approx. 9,500 SF office, 4,500 SF mission‑critical lab space, and 7,000 SF warehouse/inspection zone
    • Security features include Security Level II: Lenel card reader system, 24‑hour CCTV, and fenced parking with 62 assigned spaces
    • Mission‑critical lab infrastructure includes 100% ducted exhaust (8 air changes/hour) and high‑purity reverse osmosis water systems
    • Power backup: 500 kW stand‑alone diesel generator plus dedicated UPS backup power
    Updated: May 20
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    Versatile Showroom Warehouse in Peninsula
    $1,100,000
    2,720 SF
    Versatile Showroom Warehouse in Peninsula

    1435 Huntington Avenue #C, South San Francisco, CA 94080

    Functional industrial space in South San Francisco's commercial hub.
    • Prime location in South San Francisco with quick access to Highways 101, 280, and 380.
    • Versatile space suitable for showroom, workspace, light industrial use, offices, design studios, or storage.
    • Flexible layout with approximately 1,560 sq. ft. on the ground floor and 1,160 sq. ft. loft area.
    • Functional design with a grade level roll‑up door for convenient loading and deliveries.
    • Suitable for owner‑user or investor.
    Updated: Mar 19
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    Combined Flex Space Units
    $799,000
    2,208 SF
    Combined Flex Space Units

    Combined flex space units with office and warehouse areas.

    451 Victory Avenue #4, South San Francisco, CA 94080

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    South San Francisco Flex Space
    $1,250,000
    2,400 SF
    South San Francisco Flex Space

    2,400 SF flex space with mezzanine and drive-in door.

    121 S Maple Ave, South San Francisco, CA

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    South San Francisco Flex Space
    $1,350,000
    3,930 SF
    South San Francisco Flex Space

    3,930 SF flex space on 5,081 SF parcel.

    Airport Boulevard, South San Francisco, CA 94080

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    Functional Industrial Building For Sale
    $1,350,000
    3,930 SF
    Functional Industrial Building For Sale

    3,930 SF industrial building with flexible space and warehouse.

    1139 Airport Boulevard, South San Francisco, CA 94080

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    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 6 Active listings in South San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Functional Brisbane Warehouse-Office Unit
    $1,099,000
    Functional Brisbane Warehouse-Office Unit

    Versatile flex space near SFO and major transportation routes.

    24-100 N Hill Dr, Brisbane, CA 94005

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    San Francisco Industrial Space Available
    $3,000,000
    8,000 SF
    San Francisco Industrial Space Available

    Industrial space with office, convenient location, and ample power.

    1355 Fitzgerald Ave, San Francisco, CA

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    Flex Space in Brisbane
    $1,600,000
    3,360 SF
    Flex Space in Brisbane

    Flex space with highway access near SFO airport.

    200 Valley Drive, Suite 33 & 34, Brisbane, CA 94005

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    Modern Industrial Building in Bayview
    $3,900,000
    8,805 SF
    Modern Industrial Building in Bayview

    Modern industrial building in San Francisco's Bayview District for sale.

    1385 Donner Avenue, San Francisco, CA 94124

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Fairfield Commercial Land Opportunity
    Contact for pricing
    8.07 Acres
    Fairfield Commercial Land Opportunity

    8.07 acres of commercial land with flexible zoning.

    535 Pittman Rd, Fairfield, CA 94534

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    Prime Commercial Land in Madera
    $675,000
    0.53 Acres
    Prime Commercial Land in Madera

    23,000 SF commercial parcels on high-visibility Olive Ave.

    116 W Olive, Madera, CA 93637

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    Sanger Industrial Development Land
    $1,025,000
    5.78 Acres
    Sanger Industrial Development Land

    5.78 acres of industrial land in Sanger, California.

    1155 Academy Avenue, Sanger, CA 93657

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    Prime Reno Commercial Land Parcel
    $892,500
    1.03 Acres
    Prime Reno Commercial Land Parcel

    1.03-acre ME-zoned land near Reno-Tahoe Airport.

    Reno, NV 89502

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    Off-Market Properties in South San Francisco, CA

    Consider similar Off-Market properties in South San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    434 Canal St
    Life science properties
    30,000 SF
    Value Estimation by Request

    434 Canal St, South San Francisco, CA 94080

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    90 Spruce Ave
    Distribution properties
    36,410 SF
    Value Estimation by Request

    90 Spruce Ave, South San Francisco, CA 94080

    View details

    South San Francisco, CA Flex Space Investment Opportunities Market Analysis

    Explore 8 flex space for sale in South San Francisco, CA, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 15,188 square feet of properties for sale, with an estimated market value of $5,849,000.

    Sale prices for business spaces in South San Francisco, CA start at $799,000, averaging $1,169,800, and reaching up to $1,350,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Warehouses 51
    Flex space 28
    Manufacturing properties 6
    Distribution centers 2

    Demographics Overview

    Population 65K
    Population Growth (5Y) -3.8%
    Median Household Income $135,966
    College Educated 26.3%

    High-Yield Neighborhoods for Investment

    Identify South San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    94080 $1.1M

    Taxes & Financing

    Tax Rate (average for all types) 1.16%
    Property Tax per SF $7.35 per SF
    Tax Rate vs County Average 0.02 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in San Mateo County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in San Mateo County

    Retail

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in South San Francisco fall within the 50,000 to 100,000 square foot range.

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