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South San Francisco, CA Flex Space for Lease

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Cost-Efficient Office Space at CA, South San Francisco - Spaces Oyster Point. Contact us today to book a tour!
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Warehouse Space with Loading Docks
Updated: Jan 24, 2025
Warehouse Space with Loading Docks

253 E Harris Ave, South San Francisco, CA 94080

$33,000/Mo
19,800 sqft 0.46 AC lot
19,800 square feet of warehouse space
Two warehouse condos with two APNs
Two loading docks plus one on‑grade level door
19‑foot clear ceiling height and 12 parking spaces
4,000‑amp main panel at 480/227 volts
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Biotech Lab and Office Suite
Updated: Jun 5
Biotech Lab and Office Suite

1 Tower Pl, South San Francisco, CA 94080

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14,674 sqft
Flex suite configured for biology lab and tissue culture use
Includes a tissue culture suite and associated lab space
Features (1) 6FT fume hood and house gases
Lab support includes Vac & CDA
Break room plus (2) conference rooms and (3) private offices
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Freestanding Industrial Warehouse
Freestanding Industrial Warehouse

100 Utah Avenue, South San Francisco, CA 94080

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120,345 sqft

Large warehouse and office facility with dock access, secured truck staging, yard space, and installed electric vehicle charging infrastructure.

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Corner Flex Warehouse with Lab Potential
Corner Flex Warehouse with Lab Potential

436 N Canal St, Unit 10, South San Francisco, CA 94080

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3,710 sqft

Corner flex/warehouse condo with 1,000 sf office, central HVAC, 400-amp power, and 9 reserved spaces.

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Insulated Flex Warehouse with Offices
Insulated Flex Warehouse with Offices

140 Beacon St, South San Francisco, CA 94080

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24,000 sqft

Insulated, fully sprinklered warehouse with office space, skylights, and multiple grade-level doors for flexible operations.

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Partially Built-Out Office and Flex Space
Partially Built-Out Office and Flex Space

1 Tower Place, South San Francisco, CA 94080

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18,748 sqft

For lease with approximately half of the office area already built out, supporting a range of business layouts.

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Flex R&D Building
Flex R&D Building

441 Victory Ave, South San Francisco, CA 94080

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1,960 sqft

R&D-oriented space is available in multiple configurations for commercial users.

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Flex Space with Biology Lab
Flex Space with Biology Lab

2 Tower Pl, South San Francisco, CA 94080

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19,608 sqft

Flex space built for lab use with a 6FT fume hood, house gases, and multiple private offices and conference rooms.

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Biology Lab Flex Suite
Biology Lab Flex Suite

2 Tower Pl, South San Francisco, CA 94080

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19,861 sqft

Flex suite built for lab use with fume hoods, dedicated support rooms, and multiple private offices.

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South San Francisco Flex Space
South San Francisco Flex Space

475 Eccles Ave, South San Francisco, CA 94080

$7.25 SF/Yr
32,400 sqft

32,400 SF flex space available for lease.

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Class A Flex Sublease
Class A Flex Sublease

333 Oyster Point Blvd, South San Francisco, CA

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30,140 sqft 8.93 AC lot

Flexible sublease with modern amenities and highway access.

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South San Francisco Flex Space
South San Francisco Flex Space

300-332 Littlefield Ave, South San Francisco, CA 94080

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10,500 sqft

11,760 SF flex space with office and warehouse areas.

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Lab/Office Flex Space
Lab/Office Flex Space

South San Francisco, CA 94080

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28,000 sqft

Life science warm shell lab and office space with flexible floor plates and surface parking available.

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South San Francisco Flex/Industrial Space
South San Francisco Flex/Industrial Space

343 Oyster Point Blvd, South San Francisco, CA

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11,573 sqft 13.95 AC lot

Flex/industrial space available for lease in South San Francisco.

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South San Francisco Lab Space
South San Francisco Lab Space

201 Haskins Way, South San Francisco, CA

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10,709 sqft 6.44 AC lot

Lab and office flex space available for lease.

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South San Francisco Flex Space
South San Francisco Flex Space

900 Gateway Blvd, South San Francisco, CA 94080

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27,777 sqft

Flex space available for rent in South San Francisco.

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South San Francisco Flex Space
South San Francisco Flex Space

619 Airport Blvd, South San Francisco, CA

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6,425 sqft 0.33 AC lot

Flex space near downtown and Caltrain with highway visibility.

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Flex Space with Lab and Tissue Culture Suites
Flex Space with Lab and Tissue Culture Suites

2 Tower Pl, South San Francisco, CA 94080

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19,986 sqft

Flex space with existing lab/office areas, mostly open biology space, and tissue culture suites.

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AV-Equipped Flex Office Suite
AV-Equipped Flex Office Suite

South San Francisco, CA 94080

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30,140 sqft

Flexible sublease in a Class A building with private offices and AV-equipped conference rooms.

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South San Francisco Industrial Space
South San Francisco Industrial Space

345-367 Swift Ave, South San Francisco, CA

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5,920 sqft 2.73 AC lot

Industrial space near Highway 101 with office and warehouse.

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South San Francisco R&D Lab
South San Francisco R&D Lab

180 Kimball Way, South San Francisco, CA

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49,838 sqft 2.71 AC lot

R&D lab with freezer rooms, offices, and conference rooms.

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Flex Industrial Space
Flex Industrial Space

363 Oyster Point Blvd, South San Francisco, CA 94080

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43,500 sqft

Flex/industrial space offering approximately 43,500 square feet available for lease.

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South San Francisco Flex Space
South San Francisco Flex Space

365 Oyster Point Blvd, South San Francisco, CA

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41,197 sqft 33.74 AC lot

Flex/Industrial space available for lease in South San Francisco.

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South San Francisco Flex Space
South San Francisco Flex Space

363 Oyster Point Blvd, South San Francisco, CA

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41,197 sqft 33.74 AC lot

Flex space available for rent in South San Francisco.

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South San Francisco, CA Flex space Lease Rates & Market Statistics

Browse 25 Flex space listings for lease in South San Francisco, CA on Realmo, a commercial real estate marketplace serving the South San Francisco area. The current inventory totals 633,721 square feet of properties — an average of ~25,350 SF per listing.

Flex space lease rates in South San Francisco range from $7.25 SF/Yr at the entry level to $20 SF/Yr at the top of the market, averaging $13.63 SF/Yr. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $13.63 SF/Yr is 34% below the California state average of $20.50 SF/Yr.

South San Francisco accounts for 15% of the 172 flex space listings currently available across San Mateo County, where nearby markets include San Francisco and Redwood City. Flex space listings make up 49% of the 51 Industrial properties currently for lease in South San Francisco, with asking rates averaging $13.63 SF/Yr — 33% below the citywide Industrial properties average of $20.24 SF/Yr. Also worth a look for tenants weighing alternatives: Other industrial properties (20 listings) and Distribution centers (3 listings) elsewhere in the South San Francisco market.

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