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South San Francisco, CA Office Spaces for Sale

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San Bruno, CA Brisbane, CA Pacifica, CA Daly City, CA Colma, CA Millbrae, CA San Francisco, CA Burlingame, CA
High-Tech Flex Facility with Labs
Updated: Jul 12
High-Tech Flex Facility with Labs

560 Eccles AVE, South San Francisco, CA 94080

$45,000,000
3.65 AC lot
2019‑built flex facility with approximately 9,500 SF of office, 4,500 SF of labs, and 7,000 SF of warehouse and inspection space
Federal government tenant secured by a 14‑year Triple Net lease
3.65‑acre site in South San Francisco’s biotech and life sciences cluster
500kW stand‑alone diesel generator with dedicated UPS backup power
Four interior dock‑high doors accommodate 53‑foot tractor‑trailers
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Industrial Warehouse with Loading Docks
Updated: Dec 5, 2024
Industrial Warehouse with Loading Docks

253 E Harris Ave, South San Francisco, CA 94080

$6,500,000
19,800 sqft 0.46 AC lot
19,800‑square‑foot industrial warehouse on 0.46 acres
Two warehouse condominiums with two APNs
Two loading docks, one grade‑level door, and 12 parking spaces
19‑foot ceilings with fire sprinklers and two ADA‑compliant restrooms
2,000‑amp main panel at 480/277 volts
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Renovated Flex Space with Loading Dock
Renovated Flex Space with Loading Dock

20-338 N Canal St, South San Francisco, CA 94080

$1,490,000
1,968 sqft

Renovated warehouse-office unit with a kitchenette, two restrooms, storage, and separate customer and loading access.

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 3 Active listings in South San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 69 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Third-Floor Office Condo with Balcony
Third-Floor Office Condo with Balcony

345 Lorton AVE 304, Burlingame, CA 94010

$875,000
720 sqft

Open office suite with a kitchenette, private outdoor space, and assigned underground parking in a maintained commercial building.

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Ground-Floor Office Unit
Ground-Floor Office Unit

5020 Mission Street Unit 1, San Francisco, CA 94112

$399,900
831 sqft 0.02 AC lot

Open-plan commercial condo with NC-3 zoning and transit access on Mission Street.

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Office-Flex Building with Roll-Up Doors
Office-Flex Building with Roll-Up Doors

838 Mitten Road, Burlingame, CA 94010

Contact for pricing
13,552 sqft

Move-in ready office and warehouse space zoned innovative industrial with gated parking and fully sprinklered interior.

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Duplex With Office Unit
Duplex With Office Unit

5480 Mission ST, San Francisco, CA 94112

$999,000

Two-unit property pairs a two-bedroom residence with flexible space for office or business use.

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Off-Market Properties in South San Francisco, CA

Consider similar Off-Market properties in South San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

163 Harris Ave
OFFICE BUILDING (MULTI-STORY)

163 Harris Ave, South San Francisco, CA 94080-6008

Estimated value:
$385,000
0.35 AC lot
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323 Miller Ave, Unit 329
PROFESSIONAL BUILDING

323 Miller Ave, South San Francisco, CA 94080-3725

Unit 329
Estimated value:
$365,000
0.18 AC lot
View details
1405 Huntington Ave
PROFESSIONAL BUILDING

1405 Huntington Ave, South San Francisco, CA 94080-5988

Estimated value:
$815,000
0.04 AC lot
View details
1475 Huntington Ave
PROFESSIONAL BUILDING

1475 Huntington Ave, South San Francisco, CA 94080-5990

Estimated value:
$1,205,000
0.03 AC lot
View details
1475 Huntington Ave Ste, Unit 200
PROFESSIONAL BUILDING

1475 Huntington Ave Ste, South San Francisco, CA 94080-5967

Unit 200
Estimated value:
$575,000
1,530 sqft 0.03 AC lot
View details
1241 Msn Rd
OFFICE BUILDING (MULTI-STORY)

1241 Msn Rd, South San Francisco, CA 94080-1397

Estimated value:
$1,545,000
4,561 sqft 0.32 AC lot
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421 Grand Ave
OFFICE BUILDING (MULTI-STORY)

421 Grand Ave, South San Francisco, CA 94080-3635

Estimated value:
$60,000
6,629 sqft 0.16 AC lot
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1435 Huntington Ave
PROFESSIONAL BUILDING

1435 Huntington Ave, South San Francisco, CA 94080-5989

Estimated value:
$400,000
3,224 sqft 3.47 AC lot
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435 Grand Ave
OFFICE BUILDING (MULTI-STORY)

435 Grand Ave, South San Francisco, CA 94080-3635

Estimated value:
$265,000
0.08 AC lot
View details
1587 San Mateo Ave
OFFICE BUILDING (MULTI-STORY)

1587 San Mateo Ave, South San Francisco, CA 94080-6500

Estimated value:
$570,000
2.44 AC lot
View details
1435 Huntington Ave Ste, Unit 337
PROFESSIONAL BUILDING

1435 Huntington Ave Ste, South San Francisco, CA 94080-5989

Unit 337
Estimated value:
$1,180,000
1,220 sqft 0.03 AC lot
View details
1165 El Camino Real
OFFICE BUILDING (MULTI-STORY)

1165 El Camino Real, South San Francisco, CA 94080-3207

Estimated value:
$275,000
0.25 AC lot
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359 El Camino Real
OFFICE BUILDING (MULTI-STORY)

359 El Camino Real, South San Francisco, CA 94080-5923

Estimated value:
$1,345,000
16,550 sqft 0.95 AC lot
View details
1265 Msn Rd
OFFICE BUILDING (MULTI-STORY)

1265 Msn Rd, South San Francisco, CA 94080-1397

Estimated value:
$375,000
0.26 AC lot
View details
1475 Huntington Ave Ste, Unit 306
PROFESSIONAL BUILDING

1475 Huntington Ave Ste, South San Francisco, CA 94080-5967

Unit 306
Estimated value:
$410,000
1,125 sqft 0.03 AC lot
View details
800 Dubuque Ave, Unit 890
OFFICE BUILDING (MULTI-STORY)

800 Dubuque Ave, South San Francisco, CA 94080-1804

Unit 890
Estimated value:
$2,240,000
112,912 sqft 5.96 AC lot
View details
160 Country Clb Dr
PROFESSIONAL BUILDING

160 Country Clb Dr, South San Francisco, CA 94080-4347

Estimated value:
$12,235,000
10,814 sqft 0.47 AC lot
View details
2 Tower Pl
OFFICE BUILDING (MULTI-STORY)

2 Tower Pl, South San Francisco, CA 94080-1826

Estimated value: by Request
350,036 sqft 2.91 AC lot
View details
Airport Blvd
OFFICE BUILDING (MULTI-STORY)

Airport Blvd, South San Francisco, CA 94080

Estimated value: by Request
2.69 AC lot
View details
100 Arroyo Dr
PROFESSIONAL BUILDING

100 Arroyo Dr, South San Francisco, CA 94080-3194

Estimated value:
$1,000,000
0.14 AC lot
View details
681 Gtwy Blvd, Unit 685
OFFICE BUILDING (MULTI-STORY)

681 Gtwy Blvd, South San Francisco, CA 94080-7015

Unit 685
Estimated value: by Request
126,971 sqft 3.04 AC lot
View details

South San Francisco, CA Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in South San Francisco, CA, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 21,768 square feet of properties for sale, with an estimated market value of $52,990,000.

Sale prices for office spaces in South San Francisco, CA start at $1,490,000, averaging $17,663,333, and reaching up to $45,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 40
Office buildings 13
Medical Office Space 2
Coworking space 1

Demographics Overview

Population 65K
Population Growth (5Y) -3.8%
Median Household Income $135,966
College Educated 26.3%

High-Yield Neighborhoods for Investment

Identify South San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
94080 $17.7M

Taxes & Financing

Tax Rate (average for all types) 1.16%
Property Tax per SF $7.35 per SF
Tax Rate vs County Average 0.02 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Mateo County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in South San Francisco fall within the 100,000+ square foot range.

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