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    South San Francisco, CA Mixed-use Properties for Sale

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    San Bruno, CA Brisbane, CA Colma, CA
    Retail/Warehouse/Development Opportunity in South San Francisco
    $2,595,000
    7,603 SF
    Retail/Warehouse/Development Opportunity in South San Francisco

    305 Airport Boulevard, South San Francisco, CA 94080

    Retail/warehouse property with development potential near Grand Ave.
    • Prime location just off Grand Ave in South San Francisco.
    • Entire block‑long property stretching from Airport Blvd to Cypress.
    • Roll‑up doors on both Airport Blvd and Cypress, plus curb cut on Cypress.
    • Versatile use: retail, warehouse, or development opportunity.
    • Interior split into two large open areas, plus office, storage, and mezzanine/loft.
    Updated: Sep 12, 2025
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    Mixed-Use Property with Restaurant
    $1,298,000
    1,584 SF
    Mixed-Use Property with Restaurant

    231 Lux Avenue, South San Francisco, CA 94080

    Mixed-use property with a long-standing restaurant and residential unit.
    • Mixed‑use property featuring a residential unit and a well‑known Mexican restaurant.
    • Turnkey restaurant business boasting nearly 40 years of success - ready for a new owner.
    • Beer and wine license included (subject to conditions).
    • Large lot with dual street access and an improved rear yard perfect for outdoor dining, accommodating 40+ guests.
    • Benefit from rental income with a 3‑bedroom, 1‑bathroom residential unit.
    Updated: Jun 19, 2025
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    Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 2 Active listings in South San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 23 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Property in Bayview
    $1,390,000
    3,150 SF
    Mixed-Use Property in Bayview

    Versatile mixed-use property with income potential in a vibrant location.

    6246 3rd St, San Francisco, CA 94124

    View details
    Mixed-Use Building Under Construction
    $3,800,000
    4,200 SF
    Mixed-Use Building Under Construction

    Live, work, or rent in this mixed-use building!

    18 Visitacion Ave, Brisbane, CA 94005

    View details
    Mixed-Use Property in Outer Mission
    $1,200,000
    3,164 SF
    Mixed-Use Property in Outer Mission

    Three-unit mixed-use property in San Francisco's Outer Mission District.

    5250-5252 Mission St, San Francisco, CA

    View details
    Mixed-Use Building in Downtown Brisbane
    $799,000
    1,800 SF
    Mixed-Use Building in Downtown Brisbane

    Mixed-use commercial building with high visibility and street parking.

    45 Visitacion Avenue, Brisbane, CA 94005

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    San Francisco Development Opportunity
    $1,200,000
    0.11 Acres
    San Francisco Development Opportunity

    Prime corner lot with potential for condo development.

    5698 Mission Street, San Francisco, CA 94112

    View details
    Prime Corner Lot in Burlingame
    $11,500,000
    11,000 SF
    Prime Corner Lot in Burlingame

    Iconic building site with development potential near downtown.

    2 Park Road, Burlingame, CA 94010

    View details
    Outer Sunset Development Opportunity
    $3,795,000
    8,250 SF
    Outer Sunset Development Opportunity

    Two adjacent parcels in high-demand Outer Sunset neighborhood.

    1385 46th Avenue, San Francisco, CA 94122

    View details
    Outer Sunset Development Opportunity
    $3,795,000
    8,250 SF
    Outer Sunset Development Opportunity

    Two parcels near Ocean Beach with development potential.

    4110 Judah Street, San Francisco, CA 94122

    View details

    Off-Market Properties in South San Francisco, CA

    Consider similar Off-Market properties in South San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    481 Grand Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.16 Acres
    Value Estimation by Request

    481 Grand Ave, South San Francisco, CA 94080-3635

    View details
    405 Grand Ave
    STORE/OFFICE (MIXED USE)
    13,566 SF Lot: 0.16 Acres
    Estimated value
    $2,255,000

    405 Grand Ave, South San Francisco, CA 94080-3623

    View details
    125 Linden Ave
    STORE/OFFICE (MIXED USE)
    6,616 SF Lot: 0.35 Acres
    Estimated value
    $1,670,000

    125 Linden Ave, South San Francisco, CA 94080-6410

    View details
    201 Baden Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.30 Acres
    Estimated value
    $1,015,000

    201 Baden Ave, South San Francisco, CA 94080-4714

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    324 Grand Ave
    STORE/OFFICE (MIXED USE)
    7,170 SF Lot: 0.13 Acres
    Estimated value
    $1,685,000

    324 Grand Ave, South San Francisco, CA 94080-3605

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    146 Maple Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Lot: 1.00 Acres
    Value Estimation by Request

    146 Maple Ave, South San Francisco, CA 94080-6302

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    195 Access Rd
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    447,048 SF Lot: 4.67 Acres
    Estimated value
    $9,200,000

    195 Access Rd, South San Francisco, CA 94080-6905

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    360 Canal St
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Lot: 0.93 Acres
    Value Estimation by Request

    360 Canal St, South San Francisco, CA 94080-4604

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    437 Grand Ave
    STORE/OFFICE (MIXED USE)
    2,135 SF Lot: 0.08 Acres
    Estimated value
    $655,000

    437 Grand Ave, South San Francisco, CA 94080-3635

    View details
    204 Magnolia Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    6,700 SF Lot: 0.16 Acres
    Estimated value
    $1,560,000

    204 Magnolia Ave, South San Francisco, CA 94080-3503

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    211 Baden Ave
    STORE/OFFICE (MIXED USE)
    44,500 SF Lot: 0.92 Acres
    Estimated value
    $10,060,000

    211 Baden Ave, South San Francisco, CA 94080-4714

    View details
    439 Grand Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.08 Acres
    Value Estimation by Request

    439 Grand Ave, South San Francisco, CA 94080-3635

    View details
    310 Miller Ave
    STORES & APARTMENTS
    1,427 SF Lot: 0.08 Acres
    Value Estimation by Request

    310 Miller Ave, South San Francisco, CA 94080-3723

    View details
    419 Grand Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.08 Acres

    419 Grand Ave, South San Francisco, CA 94080-3635

    View details
    308 Linden Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.03 Acres
    Value Estimation by Request

    308 Linden Ave, South San Francisco, CA 94080-3713

    View details
    305 Linden Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.07 Acres
    Value Estimation by Request

    305 Linden Ave, South San Francisco, CA 94080-3714

    View details
    111 Pine Ave
    14,087 - 28,174 SF of Space Available in South San Francisco, CA 94080
    Value Estimation by Request

    111 Pine Ave, South San Francisco, CA 94080, South San Francisco, CA 94080

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    113 Linden Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Lot: 1.21 Acres
    Value Estimation by Request

    113 Linden Ave, South San Francisco, CA 94080-6410

    View details
    590 Dubuque Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Lot: 0.47 Acres
    Value Estimation by Request

    590 Dubuque Ave, South San Francisco, CA 94080-1824

    View details
    33 Arroyo Dr
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Lot: 1.92 Acres
    Value Estimation by Request

    33 Arroyo Dr, South San Francisco, CA 94080-3153

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    252 Armour Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Lot: 0.36 Acres
    Value Estimation by Request

    252 Armour Ave, South San Francisco, CA 94080-2802

    View details
    517 Airport Blvd
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    499,968 SF Lot: 1.86 Acres
    Estimated value
    $10,310,000

    517 Airport Blvd, South San Francisco, CA 94080-6920

    View details

    South San Francisco, CA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 25 mixed-use properties for sale in South San Francisco, CA on our real estate platform. These investment opportunities span a total of 9,187 square feet of properties for sale, with an estimated market value of $3,893,000.

    Sale prices for multi use buildings in South San Francisco, CA start at $1,298,000, averaging $1,946,500, and reaching up to $2,595,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Property Size Breakdown

    The majority of commercial real estate listings in South San Francisco fall within the 50,000 to 100,000 square foot range.

    Demographics Overview

    Population 65K
    Population Growth (5Y) -3.8%
    Median Household Income $135,966
    College Educated 26.3%

    High-Yield Neighborhoods for Investment

    Identify South San Francisco submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    94080 $1.9M

    Taxes & Financing

    Tax Rate (average for all types) 1.16%
    Property Tax per SF $7.35 per sq ft
    Tax Rate vs County Average 0.02 pp below county avg
    Average Loan-to-Value 65.0%

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