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South San Francisco, CA

Mixed-Use

South San Francisco, CA Mixed-use Properties for Sale

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San Bruno, CA Brisbane, CA Corning, CA Pacifica, CA Daly City, CA Colma, CA Millbrae, CA San Francisco, CA

NNN Government Operations Facility

Updated: Apr 23

NNN Government Operations Facility

560 Eccles Avenue, South San Francisco, CA 94080

$45,000,000

21,552 sqft 3.65 AC lot

21,552 SF high‑tech facility on a 3.65‑acre site, built in 2019
Secured 14‑year federal government tenancy under a Triple Net lease
Approximately 9,500 SF office, 4,500 SF laboratory, and 7,000 SF warehouse and inspection space
500kW stand‑alone diesel generator with dedicated UPS backup power
Four interior dock‑high doors accommodate 53‑foot tractor‑trailers

Mixed-Use Property with Restaurant

Updated: Jun 19, 2025

Mixed-Use Property with Restaurant

231 Lux Avenue, South San Francisco, CA 94080

$1,298,000

1,584 sqft

Mixed‑use property featuring a residential unit and a well‑known Mexican restaurant.
Turnkey restaurant business boasting nearly 40 years of success - ready for a new owner.
Beer and wine license included (subject to conditions).
Large lot with dual street access and an improved rear yard perfect for outdoor dining, accommodating 40+ guests.
Benefit from rental income with a 3‑bedroom, 1‑bathroom residential unit.

Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads

Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 2 Active listings in South San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 23 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mixed-Use Property with Showroom

Mixed-Use Property with Showroom

3832 Bayshore BLVD, Brisbane, CA 94005

$3,280,000

2,357 sqft

Two buildings combine residential units with showroom and warehouse space, supported by separate metering and on-site parking.

Mixed-Use Property with Retail Buildings

Mixed-Use Property with Retail Buildings

23 Visitacion AVE, Brisbane, CA 94005

$3,688,000

0.34 AC lot

Five legal lots span two street frontages with existing retail and restaurant improvements.

Mixed-Use Property with Commercial Space

Mixed-Use Property with Commercial Space

5680 Mission Street, San Francisco, CA 94112

$2,100,000

3,306 sqft

Ground-floor commercial space is paired with residential units featuring laundry hookups and a two-car garage.

Duplex With Office Unit

Duplex With Office Unit

5480 Mission ST, San Francisco, CA 94112

$999,000

Two-unit property pairs a two-bedroom residence with flexible space for office or business use.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Development Opportunity in North Beach

Development Opportunity in North Beach

65 Fresno St, San Francisco, CA 94133

$2,250,000

0.08 AC lot

Prime San Francisco location, ideal for residential development.

Oakland Vacant Apartment Land

Oakland Vacant Apartment Land

1041 7Th Ave, Oakland, CA 94607

$275,000

0.17 AC lot

Vacant 7,500 sqft lot zoned for apartments.

Oakland Development Opportunity on San Pablo

Oakland Development Opportunity on San Pablo

2625 San Pablo Avenue, Oakland, CA 94607

$450,000

0.23 AC lot

Two contiguous parcels for multifamily or mixed-use development.

Prime Commercial Lot Downtown Concord

Prime Commercial Lot Downtown Concord

2383 Salvio St, Concord, CA 94520

$750,000

Commercial lot in revitalized urban core near Todos Santos Plaza.

Off-Market Properties in South San Francisco, CA

Consider similar Off-Market properties in South San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

481 Grand Ave

STORE/OFFICE (MIXED USE)

481 Grand Ave, South San Francisco, CA 94080-3635

Estimated value:

$330,000

0.16 AC lot

405 Grand Ave

STORE/OFFICE (MIXED USE)

405 Grand Ave, South San Francisco, CA 94080-3623

Estimated value:

$2,360,000

13,566 sqft 0.16 AC lot

125 Linden Ave

STORE/OFFICE (MIXED USE)

125 Linden Ave, South San Francisco, CA 94080-6410

Estimated value:

$1,730,000

6,616 sqft 0.35 AC lot

201 Baden Ave

STORE/OFFICE (MIXED USE)

201 Baden Ave, South San Francisco, CA 94080-4714

Estimated value:

$930,000

0.30 AC lot

324 Grand Ave

STORE/OFFICE (MIXED USE)

324 Grand Ave, South San Francisco, CA 94080-3605

Estimated value:

$1,685,000

7,170 sqft 0.13 AC lot

146 Maple Ave

MIXED USE (COMMERCIAL/INDUSTRIAL)

146 Maple Ave, South San Francisco, CA 94080-6302

Estimated value:

$280,000

1.00 AC lot

195 Access Rd

MIXED USE (COMMERCIAL/INDUSTRIAL)

195 Access Rd, South San Francisco, CA 94080-6905

Estimated value:

$9,200,000

447,048 sqft 4.67 AC lot

360 Canal St

MIXED USE (COMMERCIAL/INDUSTRIAL)

360 Canal St, South San Francisco, CA 94080-4604

Estimated value:

$370,000

0.93 AC lot

437 Grand Ave

STORE/OFFICE (MIXED USE)

437 Grand Ave, South San Francisco, CA 94080-3635

Estimated value:

$655,000

2,135 sqft 0.08 AC lot

204 Magnolia Ave

MIXED USE (COMMERCIAL/INDUSTRIAL)

204 Magnolia Ave, South San Francisco, CA 94080-3503

Estimated value:

$305,000

6,700 sqft 0.16 AC lot

211 Baden Ave

STORE/OFFICE (MIXED USE)

211 Baden Ave, South San Francisco, CA 94080-4714

Estimated value:

$10,060,000

44,500 sqft 0.92 AC lot

439 Grand Ave

STORE/OFFICE (MIXED USE)

439 Grand Ave, South San Francisco, CA 94080-3635

Estimated value:

$300,000

0.08 AC lot

310 Miller Ave

STORES & APARTMENTS

310 Miller Ave, South San Francisco, CA 94080-3723

Estimated value:

$380,000

1,427 sqft 0.08 AC lot

419 Grand Ave

STORE/OFFICE (MIXED USE)

419 Grand Ave, South San Francisco, CA 94080-3635

Estimated value:

$245,000

0.08 AC lot

308 Linden Ave

STORE/OFFICE (MIXED USE)

308 Linden Ave, South San Francisco, CA 94080-3713

Estimated value:

$255,000

0.03 AC lot

305 Linden Ave

STORE/OFFICE (MIXED USE)

305 Linden Ave, South San Francisco, CA 94080-3714

Estimated value:

$235,000

0.07 AC lot

111 Pine Ave, South San Francisco, CA 94080

Industrial live-work properties

111 Pine Ave, South San Francisco, CA 94080, South San Francisco, CA 94080

Estimated value: by Request

113 Linden Ave

MIXED USE (COMMERCIAL/INDUSTRIAL)

113 Linden Ave, South San Francisco, CA 94080-6410

Estimated value:

$370,000

1.21 AC lot

590 Dubuque Ave

MIXED USE (COMMERCIAL/INDUSTRIAL)

590 Dubuque Ave, South San Francisco, CA 94080-1824

Estimated value:

$355,000

0.47 AC lot

33 Arroyo Dr

MIXED USE (COMMERCIAL/INDUSTRIAL)

33 Arroyo Dr, South San Francisco, CA 94080-3153

Estimated value: by Request

1.92 AC lot

252 Armour Ave

MIXED USE (COMMERCIAL/INDUSTRIAL)

252 Armour Ave, South San Francisco, CA 94080-2802

Estimated value:

$305,000

0.36 AC lot

517 Airport Blvd

MIXED USE (COMMERCIAL/INDUSTRIAL)

517 Airport Blvd, South San Francisco, CA 94080-6920

Estimated value:

$10,310,000

499,968 sqft 1.86 AC lot

South San Francisco, CA Mixed-Use Properties Market Trends and Statistics

Explore 25 mixed-use properties for sale in South San Francisco, CA on our real estate platform. These investment opportunities span a total of 23,136 square feet of properties for sale, with an estimated market value of $46,298,000.

Sale prices for multi use buildings in South San Francisco, CA start at $1,298,000, averaging $23,149,000, and reaching up to $45,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 65K

Population Growth (5Y) -3.8%

Median Household Income $135,966

College Educated 26.3%

High-Yield Neighborhoods for Investment

Identify South San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
94080	$23.1M

Taxes & Financing

Tax Rate (average for all types) 1.16%

Property Tax per SF $7.35 per SF

Tax Rate vs County Average 0.02 pp below county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Mateo County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in South San Francisco fall within the 50,000 to 100,000 square foot range.

How Realmo verifies these figures

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