Commercial Real Estate Market in South San Francisco, CA
Updated monthly: sale, lease, property records, location trend, and more… · Last update: September 30
145 active listings and 1,573 off-market properties in South San Francisco, CA. Commercial property asks $317/SF to buy and $25.90/SF/Yr to lease.
Market Trends
South San Francisco, CA spans 10.2 square miles in San Mateo County, California. Figures below refresh monthly; last updated 30 September 2026.
Office
Office space in South San Francisco, CA asks $482/SF to buy. Vacancy runs 20.8% across the West region in 2025, up from 11% in 2019.
Average Sale Price $/SF
Listings
Vacancy Rate % in West region
Retail
Retail space in South San Francisco, CA asks $538/SF to buy. Vacancy runs 5.8% across the West region in 2025, down from 7% in 2020.
Average Sale Price $/SF
Listings
Vacancy Rate % in West region
Industrial
Industrial vacancy in South San Francisco, CA runs 7.9% across the West region in 2025, up from 3.7% in 2019. Nearly 3.2x the 2022 low of 2.5%.
Vacancy Rate % in West region
Multifamily
Multifamily space in South San Francisco, CA asks $671/SF to buy. Vacancy runs 8.6% across the West region in 2025, up from 7% in 2022.
Average Sale Price $/SF
Listings
Vacancy Rate % in West region
Market overview
Demographics & Economy
South San Francisco, CA has 66,592 residents in 23,364 households. Density runs 6,543 people per square mile. Median household income here is $135,966 and median gross rent $2,840 a month.
66,592
Population
23,364
Households
2.9
Avg Household Size
40
Median Age
40%
College-Educated
86%
High-School Grad
10.2 sq mi
ZIP Area
6,543
Density / Sq Mi
$135,966
Median Household Income
$61,138
Median Earnings
$2,840
Median Rent
$1,159,500
Median Home Value
Tools
Nearby Markets
| Market | Average Sale Price, $/SF | Average Lease Price, $/SF/Yr |
|---|---|---|
| S San Francisco | — | $25.90 |
| San Bruno | — | — |
| Brisbane | — | — |
Commercial property in South San Francisco, CA asks $317/SF.
Frequently Asked Questions
What is the average price per square foot for commercial property in South San Francisco?
Commercial property in South San Francisco, CA asks an average of $317 per square foot. Multifamily carries the highest asking price at $671/SF.
How much does it cost to lease commercial space in South San Francisco?
Asking lease rates in South San Francisco, CA average $25.90 per square foot per year.
Where does Realmo's South San Francisco market data come from?
Realmo compiles South San Francisco, CA figures from 3 recent recorded sales, 35 active sale listings, 110 active lease listings, 1,573 tracked off-market properties. Sale and lease figures refresh monthly; vacancy annually. Last updated 30 September 2026.
Methodology & data sources
- Asking prices and averages
- Computed from 35 active for-sale and 110 active for-lease listings in South San Francisco, CA. These are ASKING figures from live listings, not closed-transaction prices, and a segment carried by a handful of listings reads as indicative rather than an average.
- Vacancy rates
- Published per-sector market series, taken at the metro level where one exists and otherwise at the Census-region level — a chart reading "in <region> region" is a regional number, not this city's.
- Refresh
- The monthly aggregates close at the end of the previous month, so 30 September 2026 — not today — is the honest last update.
- Known limitations
- office vacancy is reported at West region level, retail vacancy is reported at West region level and industrial vacancy is reported at West region level.
- Coverage
- Metrics below the 10-observation threshold fall back one geographic level. The geography used is named on each figure.
Compiled by the Realmo Data team · reviewed 30 September 2026 · report a data issue
