Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers

    560 Eccles AVE, South San Francisco, CA 94080

    View on Map
    Claim this Listing
    New
    For Sale
    $48,000,000

    Commercial Property - SOUTH SAN FRANCISCO, CA

    Property size:
    21,552 SF
    Lot size:
    3.65 Acres
    Price / SF:
    $2,227/SF
    Added:
    May 20, 2026
    Days on Market:
    2
    Last Refresh:
    May 21 at 7:06 am

    Property Features for 560 Eccles AVE

    General Information

    Property type
    Commercial Sale
    Property subtype
    Other
    Zoning
    MH00M2
    Rooms
    Office
    Parking
    62
    Parking features
    Garage, Guest
    Security features
    Security Alarm, Security Gate
    Interior features
    Bathroom Features, Elevator / Lift, Grab Bars, Kitchen Features, Parking, Wheelchair Access, Wide Halls / Doors (3 Ft +), High Ceiling, Other, Closed Circuit Monitoring (24-hour), Controlled / Secured Access, Fire System - Suppression, Security Alarm, Security Building, Security Gate With Guard
    Fencing
    Gate
    Accessibility
    Accessible Approach with Ramp, Accessible Elevator Installed
    Standard status
    Active
    Size
    21,552 SF
    Lot size
    3.65 Acres

    Utilities

    Heating system
    Forced Air
    Cooling system
    Central Air, Other (Cooling)

    Building Details

    Year built
    2019
    Flooring type
    Carpet, Concrete, Other
    Roof type
    Elastomeric, Flat, Metal, Other
    Architectural style
    Other

    We can help!

    Listing Contact
    John Tran

    Listing agent John Tran License #02092278

    Listing office KW Elevate 5201 Great America Pkwy, Suite 138, Santa Clara, CA

    Listing date May 20, 2026

    MLS# ML82044309 Listing URL

    Copyright © 2026 MLS Listings, Inc. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

    HighLights

    • Mission‑critical biotech facility with a federal tenant, providing a secure and stable investment.
    • Purpose‑built in 2019 with specialized laboratory infrastructure including entomology and botany labs with high‑purity reverse osmosis water systems.
    • Advanced security features including Lenel card reader system, 24‑hour CCTV, shatter‑resistant blast‑mitigation windows, and fenced parking.
    • Redundant power systems with a 500kW stand‑alone diesel generator and dedicated UPS backup.
    • Streamlined logistics with 4 interior dock‑high doors and a secure devanning area for 53‑foot tractor‑trailers.
    • Located in the heart of the global biotech cluster with immediate access to major Bay Area transit corridors.
    Property Profile Insight Report Location Intelligence

    Current Use by Public Records

    USDA-APHIS, Veterinary Services, ... Government Office USDA Animal and Plant ... Government Office

    Suggested Use

    Restaurant Real Estate Agency Law Firm Spa & Massage Center Building Supply Dental Office Hair Salon Auto Repair Shop Big Box & Wholesale Store Nail Salon

    Zoning and permitted uses should be independently verified with local authorities.

    Location Insight

    • Map
    • Local Demand
    City
    South San Francisco
    County
    San Mateo
    State
    California
    Longitude
    -122.39091
    Latitude
    37.659347

    Nearby Similar for Sale

    • $1,100,000
      2,720 SF

      Versatile Showroom Warehouse in Peninsula

      Functional industrial space in South San Francisco's commercial hub.
      1435 Huntington Avenue #C, South San Francisco, CA 94080
      View Details
    • $799,000
      2,208 SF

      Combined Flex Space Units

      Combined flex space units with office and warehouse areas.
      451 Victory Avenue #4, SOUTH SAN FRANCISCO, CA 94080
      View Details
    • $2,395,000
      7,017 SF

      South San Francisco Apartment Building

      7-unit apartment building in South San Francisco's downtown area.
      515 Baden Avenue, South San Francisco, CA 94080
      View Details
    • $2,595,000
      7,603 SF

      Retail/Warehouse/Development Opportunity in South San Francisco

      Retail/warehouse property with development potential near Grand Ave.
      305 Airport Boulevard, South San Francisco, CA 94080
      View Details
    • $1,980,000
      7,017 SF

      South San Francisco Apartment Building

      7-unit apartment building in booming downtown South San Francisco.
      515 Baden Avenue, SOUTH SAN FRANCISCO, CA 94080
      View Details
    • $848,000
      1,216 SF

      Retail Space Below Luxury Condos

      Retail spaces available below newly constructed luxury residential condos.
      889 McLellan Dr, South San Francisco, CA
      View Details
    • Contact for pricing
      33,000 SF

      South San Francisco Warehouse Opportunity

      Value-add warehouse facility with upside potential in South San Francisco.
      1373 Lowrie Ave, South San Francisco, CA 94080
      View Details
    • $1,699,000
      3,010 SF

      Freestanding Office Building For Sale

      Freestanding office building in South San Francisco, delivered vacant.
      161 El Camino Real, South San Francisco, CA
      View Details
    • $3,899,999
      6,774 SF

      South San Francisco SRO Hotel

      29-room hotel near downtown South San Francisco.
      MILLER AVE, South San Francisco, CA 94080
      View Details
    • $3,250,000
      7,924 SF

      South San Francisco Multifamily Investment

      Seven-unit apartment building in downtown South San Francisco.
      514 Baden Avenue, SOUTH SAN FRANCISCO, CA 94080
      View Details
    • $5,000,000
      8,000 SF

      South San Francisco Warehouse Opportunity

      8,000 sqft warehouse/industrial property in South San Francisco for sale.
      435 Grand Avenue, SOUTH SAN FRANCISCO, CA 94080
      View Details
    • $1,250,000
      2,400 SF

      South San Francisco Flex Space

      2,400 SF flex space with mezzanine and drive-in door.
      121 S Maple Ave, South San Francisco, CA
      View Details

    FAQs

    Where is this manufacturing property located?
    The property is located at 560 Eccles AVE South San Francisco, CA.
    What is the asking price?
    The asking price for this property is $48,000,000.
    What are key features of this property?
    This property features: Mission‑critical biotech facility with a federal tenant, providing a secure and stable investment.; Purpose‑built in 2019 with specialized laboratory infrastructure including entomology and botany labs with high‑purity reverse osmosis water systems.; Advanced security features including Lenel card reader system, 24‑hour CCTV, shatter‑resistant blast‑mitigation windows, and fenced parking.
    (408) 931-0897
    We can help!
    Listing Contact
    John Tran
    Real Estate License ID: 02092278
    Learn More
    Request Owner's contact information
    Message sent successfully
    Error
    If you are the owner or broker of this property and would like to edit or remove this listing please send a message to web site administrator.
    Message sent successfully
    Error
    Email to Your Friends
    Link copied to clipboard
    Separate multiple addresses with a comma
    Message sent successfully
    Error

    Realmo Value Estimations

    Realmo estimates a property’s market value using a proprietary methodology that incorporates public data and user-submitted information. This cumulative value is generated by integrating a variety of conventional and innovative methods. 

    Disclaimer

    These figures are not official appraisals and should not be used as a substitute for a valuation performed by a licensed appraiser.
    Actual market value may differ due to factors not captured in the data. Estimates are offered for informational purposes only, and users should conduct independent research before making financial or investment decisions.
    By using this feature, you acknowledge that Realmo is not responsible for actions taken based on these estimates.

    AI approach

    Realmo AI Method estimates property value using machine learning models trained on millions of comparable listings, transactions, and market signals. It analyzes property features, location intelligence data, and current market dynamics to predict the most probable market value in real time.

    Realmo CapRate Calculation

    Realmo calculates the Capitalization Rate (Cap Rate) to help estimate a property's potential return on investment. The Cap Rate is a fundamental metric in commercial real estate that measures the relationship between a property's net operating income and its market value.

    How We Calculate Cap Rate

    Cap Rate Formula:
    Cap Rate (%) = (Net Operating Income / Property Value) × 100

    Net Operating Income (NOI) Formula:
    NOI = Area × Lease Rate × (1 - Vacancy Rate) × (1 - Operating Expense Ratio)

    Components

    Net Operating Income (NOI) represents the annual income a property generates after operating expenses:

    • Area: Building square footage from property records
    • Lease Rate: Annual $/sqft based on market data for the property type and geographic location
    • Vacancy Rate: Percentage of unoccupied space based on market data for the property type and location
    • Operating Expense Ratio: Operating costs as a percentage of income, varies by property type

    Property Value is derived from:

    • Recent sale price (if available)
    • Statistical models using comparable sales
    • AI-powered valuation estimates

    Example Calculation

    For a 100,000 sqft Office Building:

    • Lease Rate: $25.00/sqft/year (market data for Office in this area)
    • Vacancy Rate: 8% (market data for Office in this area)
    • Operating Expense Ratio: 35% (typical for Office properties)
    • Property Value: $15,000,000

    Step 1: Calculate NOI

    NOI = 100,000 × $25.00 × (1 - 0.08) × (1 - 0.35)
    NOI = 100,000 × $25.00 × 0.92 × 0.65
    NOI = $1,495,000/year

    Step 2: Calculate Cap Rate

    Cap Rate = ($1,495,000 / $15,000,000) × 100
    Cap Rate = 9.97%

    Property Type Considerations

    Net Operating Income calculations vary by property type due to different operating expense ratios:

    • Office: Higher expenses (30-40%) for HVAC, utilities, maintenance
    • Retail: Moderate expenses (25-35%) for common area maintenance
    • Industrial/Warehouse: Lower expenses (15-25%) for minimal tenant services
    • Multifamily: Moderate expenses (35-45%) including property management
    • Self-Storage: Lower expenses (25-35%) due to minimal maintenance

    Market lease rates and vacancy rates are specific to each property type and geographic location, reflecting local market conditions.

    Disclaimer

    These calculations are estimates for informational purposes only and should not be used as a substitute for professional financial analysis or appraisal.

    • Cap Rate calculations depend on market data that may change over time
    • Actual operating expenses, lease rates, and vacancy rates may differ from market averages
    • Individual property conditions, lease terms, and tenant quality significantly impact actual NOI
    • Property value estimates are approximations and not official appraisals
    • Cap rates vary widely by market, property condition, and investment risk profile

    Professional Guidance Recommended: Before making any investment or financial decisions, consult with licensed appraisers, commercial real estate brokers, and financial advisors who can evaluate your specific property and circumstances.
    By using this feature, you acknowledge that Realmo is not responsible for investment decisions or actions taken based on these estimates.

    Cap approach

    Capitalization Method calculates value based on estimated net operating income (NOI) and applying a market-based capitalization rate (cap rate), we estimate what a typical investor might be willing to pay for it.

    Comparable approach

    Comparable estimate is based on recent sales of similar nearby properties, adjusted for factors like size, condition, and location.

    Relative

    Relative property class coefficient uses factors that account for typical price differences between various asset types (e.g., retail vs. industrial) to provide a more accurate market-aligned estimate.

    Geo

    Comparable Sales Method, enhanced by Geo coefficients — location-based adjustment factors that reflect differences in price levels across neighborhoods, cities, or regions ensuring a more accurate, market-sensitive valuation.

    Stat Estimate

    This method estimates value based on actual market adjusted recent (~5 years) sales of comparable properties around by location and property type.

    • Ranges - area data calculated by industry standard IQR Outlier Removal Method
    • Range-from: 75% of all similar sales ($/sqft) are above this value
    • Range-to: 75% of all similar sales ($/sqft) are below this value
    AI Estimate

    This method estimates value based on AI market estimation of comparable properties around by location and property type.

    • Ranges - area data calculated by industry standard IQR Outlier Removal Method
    • Range-from: 75% of all estimations ($/sqft) are above this value
    • Range-to: 75% of all estimations ($/sqft) are below this value
    Alternative use

    Estimate considers the property’s potential value if used for a different purpose-based on zoning, demand, and market feasibility.

    More about this property
    Thanks! Your message was sent.
    Error! Your message wasn't sent.
    Please enter your name
    Please enter email
    Please enter the email in the correct format
    Please enter phone
    Please enter the number in the correct format
    Please enter message
    Thank You

    You are Unsubscribed From Notifications

    Thank You for Inquiry
    560 Eccles AVE, SOUTH SAN FRANCISCO, CA 94080
    letter with green check mark
    Check your email
    We sent you the
    agent's contact details. yellow underline
    Can't find it?
    Please check your junk/spam folder.
    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!