Industrial

South San Francisco, CA Industrial Properties for Lease

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Cost-Efficient Office Space at CA, South San Francisco - Spaces Oyster Point. Contact us today to book a tour!
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Warehouse Space with Loading Docks
Updated: Jan 24, 2025
Warehouse Space with Loading Docks

253 E Harris Ave, South San Francisco, CA 94080

$33,000/Mo
19,800 sqft 0.46 AC lot
19,800 square feet of warehouse space
Two warehouse condos with two APNs
Two loading docks plus one on‑grade level door
19‑foot clear ceiling height and 12 parking spaces
4,000‑amp main panel at 480/227 volts
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South San Francisco Industrial Space
Updated: Nov 22, 2025
South San Francisco Industrial Space

930 Linden Avenue, South San Francisco, CA 94080

$19,700/Mo
9,975 sqft
Downtown Mixed‑use Zoning
Less than 1 mile to US‑101 (South/North)
1 mile to Caltrain station
0.2 mile to SamTrans
West of Hwy 101
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Biotech Lab and Office Suite
Biotech Lab and Office Suite

1 Tower Pl, South San Francisco, CA 94080

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14,674 sqft

Flex suite configured as a biology lab and tissue culture space with office areas and multiple conference rooms.

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Freestanding Industrial Warehouse
Freestanding Industrial Warehouse

100 Utah Avenue, South San Francisco, CA 94080

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120,345 sqft

Large warehouse and office facility with dock access, secured truck staging, yard space, and installed electric vehicle charging infrastructure.

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Distribution Center with HVAC Office
Distribution Center with HVAC Office

275 South Maple Avenue, South San Francisco, CA 94080

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70,000 sqft

Sprinklered distribution facility with dedicated offices, conference space, and warehouse racking.

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Corner Flex Warehouse with Lab Potential
Corner Flex Warehouse with Lab Potential

436 N Canal St, Unit 10, South San Francisco, CA 94080

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3,710 sqft

Corner flex/warehouse condo with 1,000 sf office, central HVAC, 400-amp power, and 9 reserved spaces.

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Insulated Flex Warehouse with Offices
Insulated Flex Warehouse with Offices

140 Beacon St, South San Francisco, CA 94080

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24,000 sqft

Insulated, fully sprinklered warehouse with office space, skylights, and multiple grade-level doors for flexible operations.

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Partially Built-Out Office and Flex Space
Partially Built-Out Office and Flex Space

1 Tower Place, South San Francisco, CA 94080

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18,748 sqft

For lease with approximately half of the office area already built out, supporting a range of business layouts.

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Flex R&D Building
Flex R&D Building

441 Victory Ave, South San Francisco, CA 94080

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1,960 sqft

R&D-oriented space is available in multiple configurations for commercial users.

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South San Francisco Warehouse Space
South San Francisco Warehouse Space

390 Swift Avenue, South San Francisco, CA 94080

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7,200 sqft

7,200 SF warehouse with office space for lease.

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Flex Space with Biology Lab
Flex Space with Biology Lab

2 Tower Pl, South San Francisco, CA 94080

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19,608 sqft

Flex space built for lab use with a 6FT fume hood, house gases, and multiple private offices and conference rooms.

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Biology Lab Flex Suite
Biology Lab Flex Suite

2 Tower Pl, South San Francisco, CA 94080

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19,861 sqft

Flex suite built for lab use with fume hoods, dedicated support rooms, and multiple private offices.

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South San Francisco Flex Space
South San Francisco Flex Space

475 Eccles Ave, South San Francisco, CA 94080

$7.25 SF/Yr
32,400 sqft

32,400 SF flex space available for lease.

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Freestanding Warehouse Building
Freestanding Warehouse Building

274 Wattis Way, South San Francisco, CA 94080

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50,000 sqft

Standalone warehouse facility available for lease in South San Francisco.

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South San Francisco Campus For Lease
South San Francisco Campus For Lease

385 Oyster Point Blvd, South San Francisco, CA 94080

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5,400 sqft

Three-building campus with office, industrial, and life science space.

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Industrial Space Available for Lease
Industrial Space Available for Lease

365 Swift Ave, South San Francisco, CA 95080

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5,920 sqft

5,920 sqft warehouse/industrial space for lease.

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Oyster Point Campus For Lease
Oyster Point Campus For Lease

389 Oyster Point Blvd, South San Francisco, CA 94080

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3,329 sqft

Three-building campus with office, industrial, and life science space.

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Class A Flex Sublease
Class A Flex Sublease

333 Oyster Point Blvd, South San Francisco, CA

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30,140 sqft 8.93 AC lot

Flexible sublease with modern amenities and highway access.

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South San Francisco Warehouse Space
South San Francisco Warehouse Space

255-263 Utah Ave, South San Francisco, CA 94080

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12,104 sqft

Industrial warehouse space with office, grade-level doors, and parking.

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South San Francisco Flex Space
South San Francisco Flex Space

300-332 Littlefield Ave, South San Francisco, CA 94080

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10,500 sqft

11,760 SF flex space with office and warehouse areas.

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South San Francisco Industrial Building
South San Francisco Industrial Building

200 Shaw Road, South San Francisco, CA 94080

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21,040 sqft

36,881 SF industrial building with freight access and prime location.

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Lab/Office Flex Space
Lab/Office Flex Space

South San Francisco, CA 94080

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28,000 sqft

Life science warm shell lab and office space with flexible floor plates and surface parking available.

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South San Francisco Industrial Campus
South San Francisco Industrial Campus

384 Oyster Point Blvd, South San Francisco, CA 94080

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2,872 sqft

Three-building campus with office, industrial, and life science space.

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Industrial Space Near Caltrain, SFO
Industrial Space Near Caltrain, SFO

1098 San Mateo Ave, South San Francisco, CA 94080

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6,644 sqft

Industrial space near Caltrain and SFO with one roll-up door.

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South San Francisco, CA Industrial properties Lease Rates & Market Statistics

Browse 51 Industrial properties for lease in South San Francisco, CA on Realmo, a commercial real estate marketplace serving the South San Francisco area. The current inventory totals 1,380,159 square feet of properties — an average of ~27,050 SF per listing.

Industrial properties lease rates in South San Francisco range from $7.25 SF/Yr at the entry level to $30 SF/Yr at the top of the market, averaging $20.24 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $20.24 SF/Yr is 9% above the California state average of $18.61 SF/Yr.

South San Francisco accounts for 20% of the 255 industrial properties currently available across San Mateo County, where nearby markets include San Francisco and Redwood City. By space type, the market includes 25 flex space listings, 20 other industrial properties and 3 distribution centers — flex space options typically offer the lowest entry point, while other industrial properties command the highest rates.

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