Southbridge, MA Commercial Real Estate for Lease

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Southbridge Industrial Warehouse Space
Updated: Nov 24, 2025
Southbridge Industrial Warehouse Space

15 Wells St, Southbridge, MA

$6 SF/Yr
17,600 sqft
17,600 square feet of industrial warehouse space available for lease.
Located in the Southbridge Innovation Center, surrounded by over 1 million square feet of facilities.
Benefit from 17‑foot clear ceiling heights.
Four loading docks for efficient operations.
Multi‑tenanted building with established international manufacturing and engineering companies.
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Office Space Available For Rent
Updated: Apr 15
Office Space Available For Rent

235 Main St, Southbridge, MA 01550

Contact for pricing
989 sqft
Contact 1‑866‑830‑4284 for property information.
Property ID: 247259‑G01
Neither USPS nor JLL shall pay cooperating brokerage commissions.
Tenant / Buyer Brokers shall seek commission compensation from the Tenant / Buyer only.
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Southbridge Office/R&D/Life Science Space
Southbridge Office/R&D/Life Science Space

80 Optical Drive, Southbridge, MA 01550

Contact for pricing
23,000 sqft

23,000 SF flexible space available for lease in Southbridge, MA.

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Southbridge Retail Spaces For Rent
Southbridge Retail Spaces For Rent

100 Central St, Southbridge, MA 01550

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Five retail spaces available in Southbridge's central business district.

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Southbridge Warehouse Space Available
Southbridge Warehouse Space Available

10 Cabot St, Southbridge, MA

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3,845 sqft

3,845 SF warehouse space for lease in Southbridge, MA.

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Southbridge Office Space Available
Southbridge Office Space Available

14 Mechanic St, Southbridge, MA

$22 SF/Yr
35,491 sqft

First-class office space with amenities in downtown Southbridge.

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Southbridge Innovation Center Flex Space
Southbridge Innovation Center Flex Space

80 Optical Drive, Southbridge, MA 01550

Contact for pricing
35,000 sqft

Flexible industrial and office space available in Southbridge Innovation Center.

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Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 7 Active listings in Southbridge, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 14 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Sturbridge Office Unit For Lease
Sturbridge Office Unit For Lease

5-113 Main St, Sturbridge, MA 01566

$1,350/Mo
750 sqft

750 SF office unit for lease in Sturbridge, MA.

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Second-Floor Office Suite
Second-Floor Office Suite

113 Main Street, #5, Sturbridge, MA 01566

$1,350/Mo
750 sqft

Well-maintained 750 SF office unit for lease with tenant-paid electricity and heat; other expenses included in rent.

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Charlton Mixed-Use Property Available
Charlton Mixed-Use Property Available

45 Sturbridge Road |, Charlton, MA 01507

Contact for pricing
3,000 sqft

3,000 SF mixed-use space for rent on Route 20.

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17.6 Acres at Signalized Corner
17.6 Acres at Signalized Corner

8 N Main St, Charlton, MA 01507

Contact for pricing

Prime commercial development opportunity in a growing residential area.

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Similar Spaces for Sale in Southbridge, MA

Consider Similar Space for Sale. We found 14 Spaces matching your search parameters.

Southbridge Retail Investment Opportunity
Southbridge Retail Investment Opportunity

121 North St, Southbridge, MA 01550

$1,916,000
12,240 sqft 1.00 AC lot

Dollar Tree property with 7.5% CAP rate in Southbridge.

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Historic Office Building For Sale
Historic Office Building For Sale

25 Elm St, Southbridge, MA 01550

$475,000
9,536 sqft

9,536 SF office building in Southbridge, Massachusetts.

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Mixed-Use Income Property with Warehouse
Mixed-Use Income Property with Warehouse

166 Mechanic St, Southbridge, MA 01550

$780,000
14,500 sqft

Mixed-use building with updated residential units, a commercial storefront, and a large paved parking area.

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Mixed-Use Property with Large Parking
Mixed-Use Property with Large Parking

166 Mechanic St, Southbridge, MA 01550

$780,000
5,733 sqft 0.28 AC lot

Updated residential units, a commercial storefront, and a warehouse/workshop with a climate-controlled two-room suite, plus large paved parking.

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Three-Story Office Building For Sale
Three-Story Office Building For Sale

326-328 Main St, Southbridge, MA

$750,000
17,432 sqft 0.17 AC lot

Turnkey office building with elevator and handicap access.

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Former Church Conversion Opportunity
Former Church Conversion Opportunity

437 Main Street, Southbridge, MA 01550

$799,000
8,476 sqft

Former church building with approximately 8,476 sq. ft., featuring prominent Main Street frontage for residential or mixed-use reuse.

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Downtown Southbridge Vintage Office Building
Downtown Southbridge Vintage Office Building

330-334 Main St, Southbridge, MA

$495,000
8,937 sqft 0.16 AC lot

Vintage office building in downtown Southbridge, suitable for office use.

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Downtown Southbridge Office Building
Downtown Southbridge Office Building

326 Main St, Southbridge, MA 01550

$750,000

Three-story office building with a private club/bar in Southbridge.

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Downtown Southbridge Office Building
Downtown Southbridge Office Building

330 Main St |, Southbridge, MA 01550

$495,000

Classic office building in downtown Southbridge, suitable for various uses.

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Downtown Southbridge Mixed-Use Building
Downtown Southbridge Mixed-Use Building

318 Main St, Southbridge, MA 01550

$549,988
20,000 sqft

Investment opportunity: 15-unit building with storefronts in revitalizing downtown.

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Machine Shop Industrial Building
Machine Shop Industrial Building

248 Elm Street, Southbridge, MA 01550

$349,000

Two-story industrial building with reinforced shop floors, loading dock, and dedicated office area for light industrial operations.

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Southbridge Industrial Building for Cultivation
Southbridge Industrial Building for Cultivation

35 Optical Drive, Southbridge, MA 01550

$4,000,000
198,300 sqft

198,300 SF industrial building suited for marijuana cultivation and manufacturing.

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Mixed-Use Property with Commercial Unit
Mixed-Use Property with Commercial Unit

33 Crystal St, Southbridge, MA 01550

$699,900

Three residential units plus a commercial unit for sale.

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Mixed-Use Multifamily Building
Mixed-Use Multifamily Building

140 Hamilton St, Southbridge, MA 01550

$1,450,000

Mixed residential and commercial building with 9 units, a street-level barbershop, office space, laundry, and off-street parking.

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Southbridge, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Southbridge, MA with 7 listings featured on our commercial real estate exchange. The current inventory includes 53,091 square feet of properties with an estimated lease value of $28 SF/Yr.

Estimated lease rates for Commercial real estate in Southbridge, MA begin at $6 SF/Yr, with an average of $14 SF/Yr and extend to $22 SF/Yr.
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