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    Sioux City, IA Commercial Real Estate for Lease

    36 results
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    Class A Office Space Available
    $15 SF/Yr
    83,200 SF

    Class A Office Space Available

    5500 Sergeant Rd, Sioux City, IA 51106

    New construction office building in Morningside area of Sioux City.

    • Class A, new construction office space in Morningside.
    • Located at the busy corner of Sunnybrook Drive and Sergeant Road, with high visibility.
    • Only one suite remaining: Suite #203 (approximately 2,216 USF sf).
    • Strategic location provides access to the greater Sioux City area and neighboring states.
    • Readily accessible via Hwy 75 Bypass and Hwy 20 via I‑29.
    Updated: Nov 12, 2025
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    Prime Corner Retail Space Available
    $8 SF/Yr
    98,446 SF

    Prime Corner Retail Space Available

    1910 Geneva St, Sioux City, IA 51103

    High-traffic corner location on Hamilton Boulevard in Sioux City.

    • A+ corner location on Hamilton Boulevard with high traffic (31,000+ vehicles per day).
    • Located across the street from a new Walgreens.
    • Multiple spaces available.
    • Completely open space, ready for finish out.
    • Established center with neighboring businesses.
    Updated: Sep 5, 2025
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    Downtown Sioux City Office Space
    $11 SF/Yr
    22,651 SF

    Downtown Sioux City Office Space

    Class A office space in a prime downtown location.

    103 S Virginia St, Sioux City, IA 51101
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    Downtown Sioux City Retail Gem
    $8 SF/Yr
    18,900 SF

    Downtown Sioux City Retail Gem

    18,900 SF Free-Standing Building, High Visibility

    124 Pierce St, Sioux City, IA 51101
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    Historic Downtown Sioux City Office
    $12 SF/Yr
    2,019 SF

    Historic Downtown Sioux City Office

    Prime Executive Office Space, Downtown Sioux City

    617 Pierce St, Sioux City, IA 51101
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    Downtown Sioux City Office Condo
    $13 SF/Yr
    5,228 SF

    Downtown Sioux City Office Condo

    Class A Office Space, Flexible Layout

    700 4Th St, Sioux City, IA 51101
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    Northside Central Creative Office Space
    $7 SF/Yr
    6,016 SF

    Northside Central Creative Office Space

    Modern Office Suite, 2,853 SF Available

    2020 Indian Hills Dr, Sioux City, IA 51104
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    Downtown Sioux City Office Space
    $12 SF/Yr
    3,500 SF

    Downtown Sioux City Office Space

    3,500 sq ft Office Suite Available

    201 Pierce St, Sioux City, IA 51101
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    Sunnybrook Drive Medical Office
    $28 SF/Yr
    6,336 SF

    Sunnybrook Drive Medical Office

    Class A Medical Office Building, Sioux City, IA

    5865 Sunnybrook Dr, Sioux City, IA 51106
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    Prime Downtown Sioux City Retail Space
    $25 SF/Yr
    4,144 SF

    Prime Downtown Sioux City Retail Space

    Brand new, 1870 sq ft retail space. Excellent location & TI allowance.

    101 Virginia St, Sioux City, IA 51101
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    Lakeport Commons Retail Space
    $19 SF/Yr
    4,800 SF

    Lakeport Commons Retail Space

    Prime Sioux City retail space available.

    5001 Sergeant Rd, Sioux City, IA 51106
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    Suite 1006: Premier Sioux City Office
    $14 SF/Yr
    181,462 SF

    Suite 1006: Premier Sioux City Office

    2,308 sq ft Executive Office Space

    600 4Th St, Sioux City, IA 51101
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    Midtown Sioux City Warehouse Space
    $3 SF/Yr
    22,135 SF

    Midtown Sioux City Warehouse Space

    Prime industrial warehouse, 4,194 SF available.

    712 Market St, Sioux City, IA 51103
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    Sioux City Industrial Space For Lease
    $9 SF/Yr
    71,240 SF

    Sioux City Industrial Space For Lease

    Modern Manufacturing/Warehouse, 13,329 SF Available

    2101 Murray St, Sioux City, IA 51111
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    Lakeport Commons Retail Space
    $16 SF/Yr
    39,098 SF

    Lakeport Commons Retail Space

    High-traffic retail center; spaces available.

    5001 Sergeant Rd, Sioux City, IA 51106
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    Historic Sioux City Office Space
    $12 SF/Yr
    12,371 SF

    Historic Sioux City Office Space

    1930s Building, 10,032 SF Available

    525 6Th St, Sioux City, IA 51101
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    Prime Medical Office Building
    $15 SF/Yr
    11,996 SF

    Prime Medical Office Building

    11,996 SF, 3,438 SF Available

    2421 Pierce St, Sioux City, IA 51104
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    Eastgate Plaza Warehouse For Sale
    $5 SF/Yr
    46,750 SF

    Eastgate Plaza Warehouse For Sale

    Spacious Sioux City warehouse, ideal for distribution.

    6023 Gordon Dr, Sioux City, IA 51106
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    Prime Sioux City Office Building
    $86 SF/Yr
    11,640 SF

    Prime Sioux City Office Building

    11,640 SF Executive Office, Hwy 20 Access

    2800 Gordon Dr, Sioux City, IA 51106
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    Medical Office Space for Lease
    $144 SF/Yr
    9,257 SF

    Medical Office Space for Lease

    Sioux City, IA medical office suite available

    1125 Pierce St, Sioux City, IA 51105
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    Downtown Sioux City Office Space
    $7 SF/Yr
    55,012 SF

    Downtown Sioux City Office Space

    Prime office suites, various sizes, attached parking.

    700 4Th St, Sioux City, IA 51101
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    Urbane 1220 Retail Space
    $11 SF/Yr
    51,986 SF

    Urbane 1220 Retail Space

    Downtown Sioux City retail space, 2,285 sq ft.

    1220 4Th St, Sioux City, IA 51103
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    Hamilton Center Retail Space
    $8 SF/Yr
    3,120 SF

    Hamilton Center Retail Space

    High-traffic retail space available.

    1901-1933 Hamilton Blvd, Sioux City, IA 51104
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    Prime Retail/Office Space Available
    $20 SF/Yr
    8,155 SF

    Prime Retail/Office Space Available

    High-end retail or office space with excellent visibility.

    1380 Hamilton Blvd, Sioux City, IA 51103
    View details

    Sioux City, IA Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Sioux City, IA with 153 listings featured on our commercial real estate exchange. The current inventory includes 44,404,166,766 square feet of properties with an estimated lease value of $658 /Mo.

    Estimated lease rates for Commercial Real Estate in Sioux City, IA begin at $2 SF/Yr, with an average of $18 SF/Yr and extend to $144 SF/Yr.

    In Sioux City, IA, current lease rates show:

    • Office Properties & Spaces positioned at $23
    • Retail properties measuring $14
    • Individual retail properties assessed at $13
    • Other office properties calculated at $19
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    Browse Commercial real estate for Lease Near Sioux City, IA

    Popular Searches in Sioux City, IA

    Most Searched ZIP Codes in Sioux City, IA

    • 51101
    • 51106
    • 51103
    • 51105
    • 51104
    • 51108
    • 51111
    • 51109

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