Sioux City, IA Healthcare Properties for Sale

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South Sioux City, NE Dakota Dunes, SD Dakota City, NE Sergeant Bluff, IA Jefferson, SD Hinton, IA Salix, IA Merrill, IA

Updated: Oct 15, 2025

Medical Office Building with Exam Rooms

1123 Pierce Street, Sioux City, IA 51105

Contact for pricing

0.57 AC lot

3,278 SF commercial space previously used as a dental office
Located in downtown Sioux City with access off busy Pierce Street
Existing layout includes a front lobby with check in/out desk, multiple exam rooms, a lab, storage, and bathrooms
Currently the lower first floor is occupied by the Prairie Pediatrics Medical Clinic
HVAC includes forced air heating and central air

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Updated: Jan 21

Renovated Wellness Studio with Two Rooms

2004 S St Aubin, Sioux City, IA 51106

Contact for pricing

0.19 AC lot

Forced air heating and central air cooling
Year built: 1919
Bright, wide‑open layout with adaptable space plus two private rooms
Two private rooms can be used for pedicure suites, nail rooms, massage therapy, esthetic services, or office space
Landlord pays water; tenant pays gas and electric billed monthly per sq ft

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Historic Hotel Building with Retail

525 6th Street, Sioux City, IA 51101

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1.50 AC lot

Restored 1930s hotel building offers about 12,400 SF of commercial space with subdivision options and ample parking.

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Former School and Church Building

6100 Morningside Ave, Sioux City, IA 51106

$4,000,000

42,000 sqft 5.00 AC lot

Former school and church property with three wings, including classrooms, a high-ceiling assembly space, and a gymnasium.

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Apartment Complex for Senior Living

5300 Stone Ave, Sioux City, IA 51106

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2.83 AC lot

70-unit apartment complex for residents 62 years and older.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 5 Active listings in Sioux City, IA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 67 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Stand-Alone Dome Office Building

109 Gaul Dr, Sergeant Bluff, IA 51054

$300,000

0.43 AC lot

Stand-alone dome building with a flexible open layout, kitchen, and two bathrooms for office or wellness-style uses.

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Versatile Retail/Office Space Available

5310 N 99th St, Omaha, NE

Contact for pricing

4,245 sqft 1.08 AC lot

Adaptable space suitable for retail, medical, or office tenants.

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Well-Maintained Medical Office Building

810 Central Ave, Hawarden, IA 51027

Contact for pricing

3,000 sqft

Built in 2007, the building includes reception, multiple exam rooms, private offices, restrooms, and staff space.

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Medical Office Investment Opportunity

15801 W Dodge Rd, Omaha, NE 68118

Contact for pricing

6,413 sqft

Freestanding medical office building with long-term net lease.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Mankato Multifamily Development Site

Agency Trail, Mankato, MN 56001

$450,000

1.44 AC lot

1.44 acre development site ideal for multifamily housing.

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Prime Vacant Land in Janesville

200 E North Street, Janesville, MN 56048

$425,000

3.00 AC lot

Three-acre vacant parcel ideal for development in Janesville, Minnesota.

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Commercial Development Land with Utilities

N 41st, Bethany, MO 64424

$432,000

16.00 AC lot

16-acre site with row crop, grass, trees, and three-phase electricity along the west side near an I-35 interchange.

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Waterfront Development Land with River Frontage

Lincoln St, Delano, MN 55328

$750,000

10.04 AC lot

River-bluff land with Crow River frontage and commercial zoning guided for residential development.

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Off-Market Properties in Sioux City, IA

Consider similar Off-Market properties in Sioux City, IA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

MEDICAL BUILDING

4224 Sergeant Rd, Sioux City, IA 51106-4600

Value Estimation by Request

4,739 sqft 0.83 AC lot

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MEDICAL BUILDING

4600 Singing Hls Blvd, Sioux City, IA 51106-9702

Value Estimation by Request

4,920 sqft 0.89 AC lot

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HOSPITAL - PRIVATE

801 5th St, Sioux City, IA 51101-1326

$26,480,000

Estimated value

361,136 sqft 2.01 AC lot

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MEDICAL BUILDING

2608 Hamilton Blvd, Sioux City, IA 51104-4048

Value Estimation by Request

1,500 sqft 0.36 AC lot

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HOMES (RETIRED, NURSING)

2121 19th St, Sioux City, IA 51103-2333

Value Estimation by Request

19,104 sqft 4.43 AC lot

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HOMES (RETIRED, NURSING)

2562 Pierce St, Sioux City, IA 51104-3706

$1,600,000

Estimated value

9,996 sqft 2.18 AC lot

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MEDICAL BUILDING

2916 Hamilton Blvd, Sioux City, IA 51104-2429

Value Estimation by Request

7,222 sqft 1.25 AC lot

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MEDICAL BUILDING

1017 7th St, Sioux City, IA 51103-5338

Value Estimation by Request

1,690 sqft 0.30 AC lot

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MEDICAL BUILDING

1855 Indian Hls Dr, Sioux City, IA 51104-1517

Value Estimation by Request

2,054 sqft 0.54 AC lot

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MEDICAL BUILDING

2300 Hamilton Blvd, Sioux City, IA 51104-4042

Value Estimation by Request

1,232 sqft 0.18 AC lot

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MEDICAL BUILDING

1206 Morningside Ave, Sioux City, IA 51106-1707

Value Estimation by Request

1,500 sqft 0.08 AC lot

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MEDICAL BUILDING

3900 Floyd Blvd, Sioux City, IA 51108-1552

Value Estimation by Request

3,335 sqft 0.70 AC lot

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HOMES (RETIRED, NURSING)

3800 Indian Hls Dr, Sioux City, IA 51104-1620

Value Estimation by Request

17,552 sqft 4.40 AC lot

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MEDICAL BUILDING

4100 Morningside Ave, Sioux City, IA 51106-2974

Value Estimation by Request

4,453 sqft 0.31 AC lot

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MEDICAL BUILDING

4000 Indian Hls Dr, Sioux City, IA 51108-1418

Value Estimation by Request

7,497 sqft 1.03 AC lot

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MEDICAL BUILDING

4801 Southern Hls Dr, Sioux City, IA 51106-4747

Value Estimation by Request

3,041 sqft 0.74 AC lot

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HOMES (RETIRED, NURSING)

4022 Indian Hls Dr, Sioux City, IA 51108-1418

Value Estimation by Request

21,905 sqft 2.92 AC lot

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HOMES (RETIRED, NURSING)

4020 Indian Hls Dr, Sioux City, IA 51108-1418

Value Estimation by Request

21,781 sqft 1.92 AC lot

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MEDICAL BUILDING

2928 Hamilton Blvd, Sioux City, IA 51104-2424

Value Estimation by Request

9,944 sqft 1.77 AC lot

View details

Sioux City, IA Healthcare Properties Market Trends and Statistics

Explore 72 healthcare properties for sale in Sioux City, IA, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 42,000 square feet of properties for sale, with an estimated market value of $4,000,000.

Sale prices for medical real estate in Sioux City, IA average $4,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 90K

Population Growth (5Y) -0.5%

Median Household Income $67,398

College Educated 18.2%

High-Yield Neighborhoods for Investment

Identify Sioux City submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
51106	$4.7M

Taxes & Financing

Tax Rate (average for all types) 2.93%

Property Tax per SF $37.17 per SF

Tax Rate vs County Average 0.09 pp above county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Woodbury County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Woodbury County

Residential Income

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Sioux City, IA Healthcare Properties for Sale

1123 Pierce Street, Sioux City, IA 51105

2004 S St Aubin, Sioux City, IA 51106

525 6th Street, Sioux City, IA 51101

6100 Morningside Ave, Sioux City, IA 51106

5300 Stone Ave, Sioux City, IA 51106

Opportunities in Nearby Cities

109 Gaul Dr, Sergeant Bluff, IA 51054

5310 N 99th St, Omaha, NE

810 Central Ave, Hawarden, IA 51027

15801 W Dodge Rd, Omaha, NE 68118

Potential Development Sites for Consideration

Agency Trail, Mankato, MN 56001

200 E North Street, Janesville, MN 56048

N 41st, Bethany, MO 64424

Lincoln St, Delano, MN 55328

Off-Market Properties in Sioux City, IA

4224 Sergeant Rd, Sioux City, IA 51106-4600

4600 Singing Hls Blvd, Sioux City, IA 51106-9702

801 5th St, Sioux City, IA 51101-1326

2608 Hamilton Blvd, Sioux City, IA 51104-4048

2121 19th St, Sioux City, IA 51103-2333

2562 Pierce St, Sioux City, IA 51104-3706

2916 Hamilton Blvd, Sioux City, IA 51104-2429

1017 7th St, Sioux City, IA 51103-5338

1855 Indian Hls Dr, Sioux City, IA 51104-1517

2300 Hamilton Blvd, Sioux City, IA 51104-4042

1206 Morningside Ave, Sioux City, IA 51106-1707

3900 Floyd Blvd, Sioux City, IA 51108-1552

3800 Indian Hls Dr, Sioux City, IA 51104-1620

4100 Morningside Ave, Sioux City, IA 51106-2974

4000 Indian Hls Dr, Sioux City, IA 51108-1418

4801 Southern Hls Dr, Sioux City, IA 51106-4747

4022 Indian Hls Dr, Sioux City, IA 51108-1418

4020 Indian Hls Dr, Sioux City, IA 51108-1418

2928 Hamilton Blvd, Sioux City, IA 51104-2424

Sioux City, IA Healthcare Properties Market Trends and Statistics

Top Commercial Asset Segments

Demographics Overview

High-Yield Neighborhoods for Investment

Taxes & Financing

Listings Trend

Total CRE Inventory on Market (SF)

Average Property Price per SF

Residential Income

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