Lee County, FL Commercial Real Estate for Lease

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Class A Office Building
Class A Office Building

12730 New Brittany Blvd, Fort Myers, FL 33907

$28 SF/Yr

Highly visible office building with full service rate.

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Class A Office Building
Class A Office Building

3301 Bonita Beach Rd SW, Bonita Springs, FL 34134

$20 SF/Yr

Premier office building with high-end finishes and convenient location.

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Fort Myers Office/Retail Space
Fort Myers Office/Retail Space

4531 Deleon Street, Fort Myers, FL 33907

Contact for pricing

Professional office/retail space in high visibility Fort Myers location.

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Premier Industrial/Warehousing Facility
Premier Industrial/Warehousing Facility

16170 Premier Pk Dr, Fort Myers, FL 33913

$15.25 SF/Yr

Class-A industrial/warehousing near Southwest Florida International Airport.

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Based on your search, we've compiled 2222 Potential Opportunities for your consideration. Besides 508 Active listings in Lee County, FL, we suggest exploring alternatives. Consider Similar 1714 Spaces for Sales.

Similar Spaces for Sale in Lee County, FL

Consider Similar Space for Sale. We found 1714 Spaces matching your search parameters.

Retail/Flex/Office Building on Del Prado
Retail/Flex/Office Building on Del Prado

4529 Del Prado Boulevard S, Cape Coral, FL 33904

$1,150,000
3,840 sqft 0.15 AC lot

3,840 SF retail/flex/office building in high-visibility location.

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Sanibel Commercial Building For Sale
Sanibel Commercial Building For Sale

2440 Palm Ridge Road, Sanibel, FL 33957

$2,700,000
4,066 sqft 0.63 AC lot

Income-producing commercial building in Sanibel's Central Business District.

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Office/Medical Suite with Spa Tenant
Office/Medical Suite with Spa Tenant

12545 New Brittany Boulevard, Fort Myers, FL 33907

$759,900
3,264 sqft 0.08 AC lot

Two updated office/medical units offer an income-leaning setup with a spa lease through 2028 and an available companion suite.

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Sanibel Island Commercial Property
Sanibel Island Commercial Property

2341 Palm Ridge Road, Sanibel, FL 33957

$1,495,000
2,827 sqft 0.08 AC lot

Highly visible commercial property in Sanibel's Town Center corridor.

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San Carlos Blvd Office Building
San Carlos Blvd Office Building

16048 SAN CARLOS BOULEVARD, Fort Myers, FL 33908

$1,100,000
3,960 sqft 0.69 AC lot

Class B office building on high-traffic San Carlos Blvd.

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C1 Flex Office and Industrial Site
C1 Flex Office and Industrial Site

3671 Fowler St, Fort Myers, FL 33901

$2,800,000
5,800 sqft 1.30 AC lot

Multiple building options on one C1-zoned site support businesses needing office space alongside flexible expansion.

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North Fort Myers Commercial Opportunity
North Fort Myers Commercial Opportunity

236 Pondella Road, North Fort Myers, FL 33903

$2,200,000
5,850 sqft 0.61 AC lot

Versatile commercial property with high visibility and multiple uses.

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Multi-Unit Professional Office Building
Multi-Unit Professional Office Building

1314-1322 Lafayette Street, Cape Coral, FL 33904

$1,295,000
0.42 AC lot

Fully leased office building configured as five units, designed for professional tenants with potential to expand.

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Restaurant on US 41 For Sale
Restaurant on US 41 For Sale

1130 N TAMIAMI TRAIL, North Fort Myers, FL 33903

$1,200,000
3,460 sqft 0.81 AC lot

Freestanding restaurant with drive-thru and high visibility on US 41.

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Auto Repair Business For Sale
Auto Repair Business For Sale

336 Gunnery Road S, Lehigh Acres, FL 33973

$1,500,000
4,300 sqft 0.61 AC lot

Auto repair business with property on high-traffic Gunnery Road.

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Two-Unit Mixed-Use Building
Two-Unit Mixed-Use Building

1615 SE 47th Terrace, Cape Coral, FL 33904

$1,072,000
0.22 AC lot

Good-condition two-unit property in the CRA district, zoned SC, currently with a bakery unit through August 2026.

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Leased Retail Center in Fort Myers
Leased Retail Center in Fort Myers

4434-4458 Cleveland Ave, Fort Myers, FL 33901

$5,500,000
22,170 sqft 2.10 AC lot

100% leased retail center with redevelopment upside.

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Corner Retail-Use Building
Corner Retail-Use Building

2730 Fowler Street, Fort Myers, FL 33901

$1,200,000
0.47 AC lot

Fully renovated corner property with flexible multi-unit configuration, strong frontage, and fenced rear lot for storage or operations.

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Professional Office with Canal Access
Professional Office with Canal Access

1218 Del Prado Boulevard S, Cape Coral, FL 33990

$749,000
0.24 AC lot

Three-office layout with a shared lobby, located at a signalized intersection with canal frontage for client-friendly access.

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Restaurant and Retail Building with Land
Restaurant and Retail Building with Land

17650 San Carlos Boulevard, Fort Myers Beach, FL 33931

$5,799,000
3.51 AC lot

For-sale commercial property with a sizable building, open-air center, and extensive frontage on San Carlos Blvd.

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Restaurant Property with Fenced Yard
Restaurant Property with Fenced Yard

916 SE 14th Avenue, Cape Coral, FL 33990

$1,498,000
0.52 AC lot

Fenced yard and existing restaurant use in a heavy industrial zoning district create flexible options for operators and owners.

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C-1 Zoned Commercial Property
C-1 Zoned Commercial Property

2959 Oleander Street, St James City, FL 33956

$750,000
0.22 AC lot

Small commercial site on Stringfellow Road, suited for retail, office, or marine-related neighborhood-serving uses.

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Class A Flex Building with 14-Foot Door
Class A Flex Building with 14-Foot Door

3820 Via Del Rey, Bonita Springs, FL 34134

$4,500,000
0.78 AC lot

Modern flex facility with high-end office buildout, reception, and a large garage/receiving bay.

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Leased Retail Building with New Roof
Leased Retail Building with New Roof

820 Cape Coral Parkway E, Cape Coral, FL 33904

$899,000
2,100 sqft 0.07 AC lot

Single-tenant retail building in Cape Coral with a recently replaced roof and an active vape shop lease.

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Entitled Mixed-Use Development Land
Entitled Mixed-Use Development Land

570 NE 4th Terrace, Cape Coral, FL 33909

$995,000
0.69 AC lot

Entitled land with approved plans for workforce housing and contractor suites, currently undeveloped.

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