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    Florence, SC Specialty Properties for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    Commercial Property Near Walmart Market
    $285,000
    2,067 SF

    Commercial Property Near Walmart Market

    822 S Cashua, Florence, SC 29501

    Commercial property for sale next to Walmart market in Florence.

    • Great location on S Cashua.
    • Next door to Walmart market.
    • Features three bathrooms.
    • Located after a strip mall.
    • Year built: 1955.
    Updated: Mar 31
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF

    McLeod Physician Associates For Sale

    1540 American Dr, Florence, SC

    2,666 SF medical office in Florence, SC for sale.

    • Secure Investment
    • Triple Net (NNN) Lease – Landlord Has Limited Responsibilities
    • Tenant Recently Extended Lease For an Additional 5 Years, showing long‑term commitment to the site
    • Located at 1540 American Drive in Florence, SC
    • 2,666 SF McLeod Physician Associates
    Updated: Jul 24, 2025
    View details
    Commercial Property on Dargan Street
    $199,000
    1,340 SF

    Commercial Property on Dargan Street

    Commercial property for sale, appointment required for showing.

    603 S Dargan St, Florence, SC 29506
    View details
    NNN Leased Plasma Investment Property
    $3,370,000
    17,174 SF

    NNN Leased Plasma Investment Property

    NNN leased investment property in Florence, South Carolina.

    1933 2nd Loop Rd, Florence, SC 29501
    View details
    Commercial Property in Downtown Area
    $199,000
    1,340 SF

    Commercial Property in Downtown Area

    Commercial property for sale in the downtown area.

    603 S 603 Dargan St, Florence, SC 29506
    View details
    Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 5 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 38 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Hartsville Retail Investment Opportunity
    $425,000
    4,500 SF

    Hartsville Retail Investment Opportunity

    4,500 sq ft building, $30,000 annual rent.

    524 Poole St, Hartsville, SC 29550
    View details
    Established Dry Cleaning Facility
    $390,000
    4,500 SF

    Established Dry Cleaning Facility

    Turnkey dry cleaning business with equipment included in sale.

    100 E Calhoun St, Dillon, SC 29536
    View details
    Hartsville Commercial Building For Sale
    $425,000
    4,500 SF

    Hartsville Commercial Building For Sale

    4,500 sq ft building near Hartsville thoroughfare.

    524 524 Poole St, Hartsville, SC 29550
    View details
    Highway Frontage Commercial Property
    $235,000

    Highway Frontage Commercial Property

    Commercial property for sale with highway frontage.

    2611 S Highway 301, Dillon, SC 29536
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 Second Loop Rd., Florence, SC 29501
    View details
    Land in Green Acres Subdivision
    $50,000
    9.00 Acres

    Land in Green Acres Subdivision

    9 acre land parcel suitable for church or development.

    956 Meadowbrook Road, Sumter, SC 29150
    View details
    40-Foot Boat Slip in Marina
    $47,995
    0.01 Acres

    40-Foot Boat Slip in Marina

    Boat slip in Friendfield Marina, Georgetown, SC, near ICW.

    Slip 19 Friendfield Marina, Georgetown, SC 29440
    View details
    Waccamaw Riverfront Land Opportunity
    $75,000

    Waccamaw Riverfront Land Opportunity

    1.66 acre land with direct river frontage on Waccamaw River.

    2027 Lees Landing Circle, Conway, SC 29526
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    4028 Irby St

    4028 Irby St

    DAY CARE, PRE-SCHOOL • 2,304 SF
    Value Estimation by Request
    4028 Irby St, Florence, SC 29505-5233
    View details
    815 2nd Loop Rd

    815 2nd Loop Rd

    VETERINARY, ANIMAL HOSPITAL • 2,325 SF
    Value Estimation by Request
    815 2nd Loop Rd, Florence, SC 29505-2826
    View details
    2120 Enterprise Dr

    2120 Enterprise Dr

    DAY CARE, PRE-SCHOOL • 4,178 SF
    Value Estimation
    $685,000
    2120 Enterprise Dr, Florence, SC 29501-1104
    View details
    2230 Jody Rd

    2230 Jody Rd

    VETERINARY, ANIMAL HOSPITAL • 4,160 SF
    Value Estimation by Request
    2230 Jody Rd, Florence, SC 29501-2046
    View details
    1410 Damon Dr

    1410 Damon Dr

    DAY CARE, PRE-SCHOOL • 4,112 SF
    Value Estimation by Request
    1410 Damon Dr, Florence, SC 29505-2651
    View details
    1180 Festival Dr

    1180 Festival Dr

    DAY CARE, PRE-SCHOOL • 5,611 SF
    Value Estimation by Request
    1180 Festival Dr, Florence, SC 29501-5597
    View details
    1310 Cashua Dr

    1310 Cashua Dr

    VETERINARY, ANIMAL HOSPITAL • 8,227 SF
    Value Estimation by Request
    1310 Cashua Dr, Florence, SC 29501-6321
    View details
    1511 Stokes Rd

    1511 Stokes Rd

    DAY CARE, PRE-SCHOOL • 2,880 SF
    Value Estimation by Request
    1511 Stokes Rd, Florence, SC 29501-7015
    View details
    1926 Irby St

    1926 Irby St

    VETERINARY, ANIMAL HOSPITAL • 3,000 SF
    Value Estimation by Request
    1926 Irby St, Florence, SC 29501-1502
    View details
    2221 2nd Loop Rd

    2221 2nd Loop Rd

    VETERINARY, ANIMAL HOSPITAL • 5,597 SF
    Value Estimation by Request
    2221 2nd Loop Rd, Florence, SC 29501-6128
    View details
    2421 Vance Dr

    2421 Vance Dr

    DAY CARE, PRE-SCHOOL • 5,220 SF
    Value Estimation by Request
    2421 Vance Dr, Florence, SC 29505-6161
    View details
    181 Palmetto St

    181 Palmetto St

    DAY CARE, PRE-SCHOOL • 3,900 SF
    Value Estimation by Request
    181 Palmetto St, Florence, SC 29506-2580
    View details
    822 Cashua Dr

    822 Cashua Dr

    DAY CARE, PRE-SCHOOL • 2,087 SF
    Value Estimation by Request
    822 Cashua Dr, Florence, SC 29501-6373
    View details
    2009 2nd Loop Rd

    2009 2nd Loop Rd

    DAY CARE, PRE-SCHOOL • 4,900 SF
    Value Estimation by Request
    2009 2nd Loop Rd, Florence, SC 29501-6124
    View details
    1335 Golf Ter Blvd

    1335 Golf Ter Blvd

    DAY CARE, PRE-SCHOOL • 4,000 SF
    Value Estimation by Request
    1335 Golf Ter Blvd, Florence, SC 29501-6263
    View details
    2111 Jody Rd

    2111 Jody Rd

    DAY CARE, PRE-SCHOOL • 6,630 SF
    Value Estimation by Request
    2111 Jody Rd, Florence, SC 29501-2031
    View details
    3516 Southborough Rd

    3516 Southborough Rd

    DAY CARE, PRE-SCHOOL • 4,050 SF
    Value Estimation by Request
    3516 Southborough Rd, Florence, SC 29501-5800
    View details
    1804 2nd Loop Rd

    1804 2nd Loop Rd

    DAY CARE, PRE-SCHOOL • 5,024 SF
    Value Estimation by Request
    1804 2nd Loop Rd, Florence, SC 29501-6121
    View details
    321 Beltline Dr

    321 Beltline Dr

    VETERINARY, ANIMAL HOSPITAL • 5,010 SF
    Value Estimation by Request
    321 Beltline Dr, Florence, SC 29501-7404
    View details

    Florence, SC Specialty Properties Investment Opportunities Market Analysis

    Explore 43 specialty properties for sale in Florence, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 646,460 square feet of properties for sale, with an estimated market value of $8,240,000.

    Sale prices for properties in Florence, SC start at $75,000, averaging $433,684, and reaching up to $890,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    • 29506

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