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Lee County, FL Retail Properties for Sale

177 results
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High-Traffic Corner Retail Opportunity
$1,495,000
0.19 Acres

High-Traffic Corner Retail Opportunity

19003 San Carlos Blvd, Fort Myers Beach, FL 33931

Prime location with high visibility and drive-through access.

  • High‑traffic corner location at the gateway to Fort Myers Beach with approximately 24,000 vehicles per day.
  • Designed for speed and volume with true drive‑through circulation and dual pass‑through ingress/egress.
  • Large on‑site parking lot to facilitate customer flow.
  • Recently updated CBS building with a new roof installed in November 2023.
  • Flexible interior bays and turnkey improvements.
Updated: Jan 4
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Turnkey Tea & Pastry Destination
$49,500
29.21 Acres

Turnkey Tea & Pastry Destination

2301 Del Prado Blvd S, Cape Coral, FL 33990

Cape Coral's Le Petit Pastry & Tea for sale.

  • Turnkey business opportunity: Le Petit Pastry & Tea is fully operational with all assets, inventory, licenses, systems, website, and branding included.
  • Prime location in the Coralwood Shopping Center, benefiting from high foot traffic and visibility due to major anchor tenants.
  • E2 Visa qualification: Ideal business for applicants seeking an E2 Visa.
  • Profitable menu and established customer base: Features a wide selection of premium teas, homemade pastries, and savory items, popular for various gatherings.
  • Smooth transition: Two experienced employees are in place to assist with the ownership transition.
Updated: Dec 10, 2025
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Estero Retail and Office Space
Contact for pricing
0.75 Acres

Estero Retail and Office Space

35,000 SF center with retail, office, and medical spaces.

21740 S Tamiami Trl, Estero, FL 33928
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Commercial Property on South Tamiami
$1,350,000
3,677 SF

Commercial Property on South Tamiami

Commercial property with prime location and multiple business opportunities.

16070 S Tamiami Trl, Fort Myers, FL 33908
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Versatile Fort Myers Commercial Property
$2,500,000
0.50 Acres

Versatile Fort Myers Commercial Property

12,000 SF industrial and retail space in Fort Myers.

2065 Towles St, Fort Myers, FL 33916
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Profitable Fort Myers Investment Opportunity
$2,025,000
0.97 Acres

Profitable Fort Myers Investment Opportunity

Free-standing, fully leased building with diverse tenants and ample parking.

3775 Fowler St, Fort Myers, FL 33901
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Bonita Springs Commercial Opportunity
$1,200,000
0.57 Acres

Bonita Springs Commercial Opportunity

Two buildings on 0.5 acres in Bonita Springs.

27831-835 Tamiami Trl, Bonita Springs, FL 34134
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Tamiami Trail Commercial Building
$1,750,000
0.83 Acres

Tamiami Trail Commercial Building

8,126 sq ft commercial building on 0.83 acres.

1357 N Tamiami Trl, North Fort Myers, FL 33903
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Matlacha Restaurant and Marina Property
Pending
$3,300,000
1.41 Acres

Matlacha Restaurant and Marina Property

Unique restaurant and marina property in the heart of Matlacha.

4520 Pine Island Rd NW, Matlacha, FL 33993
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Established Restaurant on US 41
$1,200,000

Established Restaurant on US 41

Upscale restaurant business for sale in Bonita Springs, Florida.

Us 41, Bonita Springs, FL 34134
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Established Vietnamese Restaurant in Cape Coral
$175,000
8.67 Acres

Established Vietnamese Restaurant in Cape Coral

Profitable, turnkey Vietnamese restaurant for sale in a prime location.

106 Hancock Bridge Pkwy W, Cape Coral, FL 33991
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Profitable Business in Fort Myers
$110,000

Profitable Business in Fort Myers

Turnkey smoothie, bubble tea, and coffee business for sale.

Undisclosed Address, Fort Myers, FL 33913
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Commercial Property Near Beach Access
$2,995,000
0.80 Acres

Commercial Property Near Beach Access

Large commercial property with remodeled building near public beach access.

6061 Estero Blvd, Fort Myers Beach, FL 33931
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Cape Coral Mixed-Use Duplex
$575,000
0.23 Acres

Cape Coral Mixed-Use Duplex

Mixed-use duplex in Cape Coral, ideal for live/work setup.

2828 Santa Barbara Blvd, Cape Coral, FL 33914
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Fort Myers Commercial Building For Sale
$699,900
0.50 Acres

Fort Myers Commercial Building For Sale

2,964 sq ft commercial building on high-traffic MLK corridor.

3050 Michigan Ave, Fort Myers, FL 33916
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Equipped Salon in Cape Coral
$70,000
0.23 Acres

Equipped Salon in Cape Coral

Fully equipped salon for sale in Cape Coral area.

SE 16Th Pl, Cape Coral, FL 33990
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Waterfront Commercial Property in Matlacha
$750,000
0.21 Acres

Waterfront Commercial Property in Matlacha

Income-producing commercial property with waterfront appeal in Pine Island.

4547 Pine Island Rd NW, Matlacha, FL 33993
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Pine Island Retail Investment Opportunity
$3,295,000
1.24 Acres

Pine Island Retail Investment Opportunity

Retail bays in established shopping center, excellent investment potential.

5110-5120 Pine Island Rd NW, Bokeelia, FL 33922
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Prime Commercial Property on Periwinkle
$5,500,000
3.00 Acres

Prime Commercial Property on Periwinkle

Commercial property with excellent exposure and road frontage on 3 acres.

1551 Periwinkle Way, Sanibel, FL 33957
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Cape Coral Commercial Opportunity
$1,050,000
0.16 Acres

Cape Coral Commercial Opportunity

Versatile commercial property in thriving Cape Coral location.

1213 SE 47Th Ter, Cape Coral, FL 33904
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Sanibel Island Income-Producing Commercial Property
$5,400,000
0.84 Acres

Sanibel Island Income-Producing Commercial Property

Income-producing commercial property on Sanibel Island with high visibility.

1039 Periwinkle Way, Sanibel, FL 33957
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Established Salon in Winn Dixie Center
$48,900

Established Salon in Winn Dixie Center

Well-established beauty salon in a convenient location.

9848 Stringfellow Rd, St James City, FL 33956
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Waterfront Commercial Property with Marina
$3,999,999
0.57 Acres

Waterfront Commercial Property with Marina

Waterfront commercial property with marina, retail, and development potential.

17671 San Carlos Blvd, Fort Myers Beach, FL 33931
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Cape Coral Restaurant and Bar
$1,700,000
0.32 Acres

Cape Coral Restaurant and Bar

Successful neighborhood restaurant and bar with real estate included.

1303 Del Prado Blvd S, Cape Coral, FL 33990
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Lee County, FL Retail Properties Investment Opportunities Market Analysis

Explore 3704 retail properties for sale in Lee County, FL, showcased through 177 active listings on our real estate platform. These investment opportunities span a total of 135,378,907 square feet of properties for sale, with an estimated market value of $2,465,122,263.

Prices for stores in Lee County, FL start at $43,000, averaging $1,347,797, and reaching up to $20,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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